Almirall S.A.

The sponsor is actively involved in research on moderate-to-severe hidradenitis suppurativa, covering both symptom burden and treatment tolerability in this difficult-to-manage inflammatory skin disorder. This area represents a major therapeutic focus within its dermatology pipeline.

• Hidradenitis suppurativa
• Inflammatory skin disease
• Disease severity and tolerability

Work in this field addresses chronic nodular and suppurative lesions, with attention to patient populations experiencing ongoing disease activity and treatment need.

Another major area of interest is actinic keratosis, including lesions on the face and scalp. The sponsor’s studies in this field are directed toward lesion clearance and the management of sun-damaged skin with precancerous change.

• Actinic keratosis
• Face and scalp lesions
• Cutaneous precancerous disease

This research area also includes attention to the risk of progression to squamous cell carcinoma in patients with actinic damage.

The portfolio includes studies in alopecia areata, with a specific focus on adults affected by severe to very severe forms of autoimmune hair loss. This reflects interest in conditions driven by immune dysregulation affecting the hair follicle.

• Alopecia areata
• Autoimmune hair loss
• Immune-mediated dermatology

These trials align with broader work in dermatologic diseases where immune pathways contribute to persistent visible symptoms and quality-of-life impact.

Beyond dermatology, the sponsor funds research in heartburn and reflux during pregnancy, with attention to maternal safety and foetal and newborn outcomes. This area extends its clinical interest into supportive care for common gastrointestinal symptoms in obstetric settings.

• Heartburn and reflux
• Pregnancy safety
• Perinatal outcomes

The sponsor also shows interest in broader inflammatory diseases, indicating a therapeutic footprint that reaches beyond skin-focused indications.