Alkermes Inc.

Address
900 Winter Street

Sponsor Overview

assignment
7
sponsored trials
science
1
molecule
location_city
41
research centres
public
12
countries
person_search
38
investigators

Specializations

Sleep-Wake Disorders

Alkermes Inc. is active in clinical research focused on narcolepsy and idiopathic hypersomnia, with studies addressing both narcolepsy type 1 and narcolepsy type 2.

  • Excessive daytime sleepiness
  • Wakefulness regulation
  • Idiopathic hypersomnia
  • Narcolepsy type 1
  • Narcolepsy type 2

The sponsor’s trial portfolio reflects a strong therapeutic interest in disorders that disrupt alertness, sleep continuity, and daytime functioning.

Narcolepsy Type 1 and Narcolepsy Type 2

Clinical activity includes separate research efforts in narcolepsy type 1 and narcolepsy type 2, indicating focused attention on the different clinical presentations of central hypersomnolence disorders.

  • Cataplexy-associated narcolepsy
  • Sleepiness-related impairment
  • Central disorders of hypersomnolence

These studies center on symptoms that affect daily alertness and functional capacity in people living with narcolepsy.

Idiopathic Hypersomnia

Alkermes also funds research in idiopathic hypersomnia, a condition marked by persistent excessive daytime sleepiness and difficulty maintaining wakefulness.

  • Daytime sleepiness
  • Wakefulness disorders
  • Sleep-related impairment

This area of interest aligns with therapeutic development for patients whose symptoms extend beyond nocturnal sleep disturbance to sustained daytime impairment.

Symptom Management in Hypersomnolence Conditions

The sponsor’s clinical research landscape emphasizes treatment of excessive daytime sleepiness across multiple hypersomnolence disorders, including narcolepsy and idiopathic hypersomnia.

  • Alertness
  • Daytime functioning
  • Sleep-wake balance

Research activity spans multiple active sites and countries, supporting investigation of therapies aimed at improving wakefulness-related symptoms in these patient groups.

Sponsored Trials

Trial Name Country Status
A Phase 2, Parallel-Group, Dose-Range-Finding Study With Randomized Double-Blind Treatment and Open-Label Periods to Evaluate the Safety and Efficacy of ALKS 2680 in Subjects With Narcolepsy Type 1Belgium BelgiumCzechia CzechiaFrance FranceItaly ItalySpain SpainThe Netherlands The NetherlandsNot Recruiting
Evaluation of ALKS 2680 Efficacy and Safety in Idiopathic Hypersomnia: A Phase 2 Randomized, Double-Blind, Dose-Range-Finding StudyBelgium BelgiumCzechia CzechiaFrance FranceItaly ItalySpain SpainThe Netherlands The NetherlandsRecruiting
Evaluation of ALKS 2680 for Safety and Efficacy in Treating Excessive Daytime Sleepiness in Narcolepsy Type 2: A Phase 2 Randomized, Double-Blind, Placebo-Controlled StudyBelgium BelgiumCzechia CzechiaFrance FranceItaly ItalySpain SpainThe Netherlands The NetherlandsNot Recruiting
Long-Term Evaluation of Safety, Tolerability, and Treatment Durability of ALKS 2680 in Patients with Narcolepsy Type 1 and Type 2Belgium BelgiumCzechia CzechiaFrance FranceItaly ItalySpain SpainThe Netherlands The NetherlandsRecruiting
Phase 3 Randomized Double‑Blind Placebo‑Controlled Trial of ALKS 2680 for Excessive Daytime Sleepiness in Adults with Narcolepsy Type 2Belgium BelgiumFrance FranceGermany GermanyItaly ItalySpain SpainThe Netherlands The NetherlandsNot Yet Recruiting
Phase 3 Randomized Double‑Blind Placebo‑Controlled Trial of ALKS 2680 for Excessive Daytime Sleepiness in Adults with Narcolepsy Type 1Austria AustriaBelgium BelgiumFinland FinlandFrance FranceGermany GermanyItaly ItalyNorway NorwayPoland PolandSpain SpainSweden SwedenThe Netherlands The NetherlandsNot Yet Recruiting
Phase 3 Randomized Double‑Blind Placebo‑Controlled Trial of ALKS 2680 for Excessive Daytime Sleepiness in Adults with Narcolepsy Type 1Belgium BelgiumFrance FranceItaly ItalySpain SpainThe Netherlands The NetherlandsRecruiting

Data & Insights

science
Molecule Portfolio
Compounds under investigation
1
Exclusive Molecules
out of 1 total (100% not shared with other sponsors)

This sponsor works with 1 molecule, of which 1 is not being studied by other sponsors.

hub
Site Partnerships
Collaboration with research centres
78%
Return partnership rate
32 of 41 sites collaborated multiple times

This sponsor has worked with 41 sites across their trial portfolio.

Therapeutic Focus

  • 1.
    Nervous System Diseases7 trials
    449 other sponsors

Partnered Research Centres

41 centres
location_city
assignment13
Advanced Sleep Research GmbH
Address
Luisenstrasse 55, Mitte, 10117 Berlin
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location_city
assignment37
Anima
Address
Alkerstraat 28, 3570 Alken
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location_city
assignment191
Az St-Jan Brugge-Oostende A.V.
Address
Ruddershove 10, 8000 Bruges
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location_city
assignment14
Berufsgenossenschaftliches Universitaetsklinikum Bergmannsheil gGmbH
Address
Buerkle De La Camp-Platz 1, Wiemelhausen, 44789 Bochum
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location_city
assignment1199
Centre Hospitalier Lyon Sud
Address
165 Chemin Du Grand Revoyet, 69310 Pierre Benite
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location_city
assignment975
Centre Hospitalier Universitaire De Bordeaux
Address
1 Rue Jean Burguet, 33000 Bordeaux
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