Academisch Ziekenhuis Maastricht

Address
P Debyelaan 25

Sponsor Overview

assignment
15
sponsored trials
science
28
molecules
location_city
16
research centres
public
2
countries
person_search
29
investigators

Specializations

Cardiovascular and Metabolic Health

The institution demonstrates significant commitment to advancing understanding and treatment of cardiovascular diseases and associated metabolic conditions. Research efforts concentrate on managing atrial fibrillation through various therapeutic approaches, including investigations into catheter ablation techniques and comparative studies of different ablation strategies. The facility explores innovative interventions for heart failure patients, examining both pharmacological and device-based treatments.

  • Atrial Fibrillation Management and Ablation Techniques
  • Heart Failure Therapeutic Interventions
  • Cardiovascular Risk Factor Modification
  • Metabolic Syndrome and Obesity Treatment

Particular attention is directed toward understanding the interplay between cardiovascular health and metabolic disorders, with studies examining obesity management and its impact on cardiac function. The research portfolio includes investigations into hypertension control and comprehensive approaches to reducing cardiovascular risk through lifestyle and medical interventions.

Gastrointestinal and Hepatobiliary Disorders

A substantial research focus addresses disorders of the gastrointestinal tract and liver function. The institution conducts extensive work on inflammatory bowel disease, particularly Crohn's disease and ulcerative colitis, exploring novel therapeutic strategies and monitoring approaches. Studies investigate the effectiveness of various treatment modalities for managing chronic intestinal inflammation and preventing disease progression.

  • Inflammatory Bowel Disease Treatment Optimization
  • Hepatic Steatosis and Liver Function
  • Gastrointestinal Motility Disorders
  • Chronic Intestinal Inflammation Management

Research extends to non-alcoholic fatty liver disease and related hepatic conditions, examining the relationship between metabolic factors and liver pathology. The facility investigates diagnostic and therapeutic approaches for various gastrointestinal functional disorders, contributing to improved patient outcomes in digestive health.

Respiratory Medicine and Sleep Disorders

The institution maintains an active research programme addressing respiratory conditions and sleep-related breathing disorders. Studies focus on obstructive sleep apnea and its cardiovascular implications, examining various treatment modalities including continuous positive airway pressure therapy and alternative interventions. Research explores the complex relationships between sleep disturbances, metabolic health, and cardiovascular outcomes.

  • Sleep Apnea Syndrome Management
  • Respiratory Function Assessment
  • Sleep Quality and Cardiovascular Interactions

Investigations encompass the impact of respiratory disorders on overall health and quality of life, with particular emphasis on identifying effective therapeutic interventions for patients with complex comorbidities involving both respiratory and cardiovascular systems.

Musculoskeletal and Rehabilitation Medicine

Research activities address conditions affecting the musculoskeletal system and rehabilitation strategies for various patient populations. The institution investigates treatment approaches for osteoarthritis, particularly focusing on knee joint pathology and interventions to improve mobility and reduce pain. Studies examine both conservative and interventional therapies for degenerative joint conditions.

  • Osteoarthritis Treatment and Management
  • Joint Function Preservation
  • Rehabilitation Protocols and Outcomes

The research portfolio includes investigations into optimizing physical rehabilitation programmes and assessing the effectiveness of various therapeutic modalities for patients recovering from illness or managing chronic musculoskeletal conditions.

Chronic Disease Management and Patient Care Optimization

The facility demonstrates commitment to improving outcomes for patients with chronic conditions through comprehensive care approaches. Research examines strategies for managing multiple comorbidities, with particular attention to the intersection of diabetes mellitus, cardiovascular disease, and metabolic disorders. Studies investigate patient monitoring techniques, adherence strategies, and integrated care models.

  • Multimorbidity Management Strategies
  • Diabetes Care and Complications Prevention
  • Patient Quality of Life Assessment
  • Integrated Care Delivery Models

Research activities focus on developing evidence-based approaches to improve long-term outcomes for patients with complex medical needs, emphasizing the importance of coordinated care and patient-centered treatment strategies across multiple disease domains.

Sponsored Trials

Trial Name Country Status
Comparative Evaluation of 68Ga-FAPI-46 and 18F-FDG as PET Tracers in Estrogen Receptor-Positive Breast Cancer: A Pilot StudyThe Netherlands The NetherlandsNot Yet Recruiting
Effect of Febuxostat Co-administration on Osimertinib Blood-Brain Barrier Penetration in Patients with EGFR-Mutated Non-Small Cell Lung CancerThe Netherlands The NetherlandsNot Yet Recruiting
Evaluation of 5-Fluorouracil and Calcipotriol Combination Therapy Versus 5-Fluorouracil Monotherapy in Actinic Keratosis: A Multicenter Randomized Controlled TrialThe Netherlands The NetherlandsNot Recruiting
Evaluation of a Single Measurement and Adjustment Strategy for Direct Oral Anticoagulants in Frail Elderly Patients with Atrial Fibrillation or Venous ThromboembolismThe Netherlands The NetherlandsRecruiting
Evaluation of Angiotensin-Converting Enzyme Inhibitor Perindopril and Valsartan on Cardiac Remodeling in Women with Asymptomatic Subclinical Heart FailureThe Netherlands The NetherlandsRecruiting
Evaluation of Intra-Arterial Autologous Mesoangioblast Administration in Patients with m.3243A>G Mutation-Induced Mitochondrial MyopathyThe Netherlands The NetherlandsNot Yet Recruiting
Evaluation of Intracranial Efficacy of JDQ443 in Patients with KRAS G12C-Mutant Non-Small Cell Lung Cancer and Brain Metastases: A Phase II StudyThe Netherlands The NetherlandsNot Recruiting
Evaluation of Intracranial Efficacy of Sacituzumab Govitecan and Bevacizumab in Asymptomatic Brain Metastases from Non-Small Cell Lung CancerThe Netherlands The NetherlandsRecruiting
Evaluation of Modified Osimertinib Dosing with Cobicistat for Pharmacokinetic Enhancement in Advanced EGFR-Mutated Non-Small Cell Lung CancerThe Netherlands The NetherlandsRecruiting
Evaluation of Perioperative Intravenous Esketamine on Postoperative Craniotomy Pain in Drug-Resistant Temporal Lobe Epilepsy: A Randomized Controlled TrialThe Netherlands The NetherlandsRecruiting
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Data & Insights

science
Molecule Portfolio
Compounds under investigation
3
Exclusive Molecules
out of 28 total (11% not shared with other sponsors)

This sponsor works with 28 molecules, of which 3 are not being studied by other sponsors.

hub
Site Partnerships
Collaboration with research centres
44%
Return partnership rate
7 of 16 sites collaborated multiple times

This sponsor has worked with 16 sites across their trial portfolio.

Therapeutic Focus

  • 1.
    Neoplasms5 trials
    853 other sponsors
  • 2.
    Respiratory Tract Diseases5 trials
    277 other sponsors
  • 3.
    Cardiovascular Diseases3 trials
    359 other sponsors
  • 4.
    Diagnosis2 trials
    83 other sponsors
  • 5.
    Eye Diseases1 trial
    138 other sponsors
  • 6.
    Genetic Phenomena1 trial
    26 other sponsors
  • 7.
    Musculoskeletal Diseases1 trial
    238 other sponsors
  • 8.
    Nervous System Diseases1 trial
    449 other sponsors
  • 9.
    Not possible to specify1 trial
    220 other sponsors
  • 10.
    Nutritional and Metabolic Diseases1 trial
    211 other sponsors
  • 11.
    Skin and Connective Tissue Diseases1 trial
    247 other sponsors

Partnered Research Centres

16 centres
location_city
assignment61
Academisch Ziekenhuis Leiden
Address
Albinusdreef 2, 2333 ZA Leiden
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location_city
assignment30
Academisch Ziekenhuis Maastricht
Address
P Debyelaan 25, 6229 HX Maastricht
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location_city
assignment137
Catharina Ziekenhuis Stichting
Address
Michelangelolaan 2, 5623 EJ Eindhoven
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location_city
assignment1
Envida
Address
Abtstraat 2a, 6211LS Maastricht
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location_city
assignment711
Erasmus Universitair Medisch Centrum Rotterdam (Erasmus MC)
Address
Dr. Molewaterplein 40, 3015 GD Rotterdam
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location_city
assignment89
Gelre Hospitals
Address
Albert Schweitzerlaan 31, 7334 DZ Zutphen
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