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Wilhelmina Childrens Hospital

Address
Lundlaan 6, 3584 EA Utrecht, The Netherlands

Wilhelmina Children's Hospital - Pediatric Immunology and Rheumatology Center

Wilhelmina Children's Hospital is a leading pediatric research center with distinguished expertise in autoimmune and inflammatory conditions affecting children. The center demonstrates particular strength in rare disease research and novel therapeutic approaches for complex pediatric rheumatologic disorders.

  • Juvenile Idiopathic Arthritis subtypes including systemic JIA, enthesitis-related arthritis, and juvenile psoriatic arthritis
  • Macrophage Activation Syndrome (MAS) and Secondary Hemophagocytic Lymphohistiocytosis (sHLH)
  • Rare genetic disorders including Alagille Syndrome and GRIN-related neurological disorders
  • Inflammatory bowel disease including Crohn's Disease in pediatric populations

The hospital conducts innovative research in biomarker-guided treatment strategies and personalized medicine approaches, particularly focusing on optimizing biologic therapies and targeted treatments. Their comprehensive portfolio includes studies evaluating novel immunomodulatory agents such as emapalumab, ixekizumab, and apremilast, as well as investigating pharmacokinetic profiles and dose optimization in pediatric patients. The center's commitment to advancing care for children with rare and life-threatening conditions positions it at the forefront of pediatric immunology and rheumatology research.

Site Overview

assignment
12
connected trials
corporate_fare
11
sponsors
science
11
IMPs

Activity Indicator

Last 6 months

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Trials started
-100% vs previous period.
2
Trials started 6–12 months ago
12
Total trials linked
Highly Active
trending_downDeclining-100%
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Apr
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Trial Flow

How this site's trials are distributed across therapeutic areas and active substances (IMPs), and how they're positioned within their overall lifecycle status. Flow thickness represents the number of unique trials.

Therapeutic areaarrow_forwardIMParrow_forwardLifecycle status

Top 5 of 6 therapeutic areas and 10 of 11 IMPs, ranked by number of trials.

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Compounds & Molecules Timeline

The time span of clinical-trial activity for the main active substances (IMPs) studied at this site over the last 8 years. Each bar runs from the earliest trial start to the most recent end; a substance with a trial still open has no recorded end and is shown as ongoing.

Trial span Ongoing Showing last 8 years
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Sponsor & Partnership

Top sponsors by active trials, and the ones that have come back for more than one study.

Active trials
8
Sponsors (total)
11
Active sponsors
8

Sponsor Network

Top 8 by active trials.

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Partnership History

Sponsors with repeated collaboration (≥ 2 trials).

Sponsor Network Graph

How sponsors and therapeutic areas connect across this site's active trials: each link is at least one active trial shared between them, and bigger nodes mean more activity. Click a node to see its exact connections.

Country Benchmark

Compared to 271 other sites in The Netherlands

description
Trial volume
12
Outperforms 71% of sites
public
Therapeutic diversity
7areas
Outperforms 75% of sites
groups
Sponsor diversity
11sponsors
Outperforms 74% of sites

Therapeutic Area Benchmark — The Netherlands

Select a therapeutic area to compare against other sites in The Netherlands.

Competitor Comparison

Similar sites in the same country running a comparable number of trials (within ±30%), scored on how closely their trial portfolios match this one. Higher percentages mean a more similar profile.

Country: The Netherlands

Market Share

Country: The Netherlands

Therapeutic Area Market Share

Select a therapeutic area to view its disease coverage breakdown.

Heat Maps & Advanced Analytics

How often specific conditions appear in trials across this site and comparable sites from the same country. Each row is a site, each column a condition, and each cell the number of trials on it — darker means more activity.

Other Trials in Wilhelmina Childrens Hospital

lock Showing 1 of 12 trials — the rest is available on a paid plan.

Trial Sponsor Phase Status Start Date End Date
Biomarker-Guided Anakinra Tapering Strategy in Pediatric Systemic Juvenile Idiopathic Arthritis: A Randomized Controlled TrialUniversitair Medisch Centrum UtrechtPhase IIINot Yet Recruiting

IMP list

lock Showing 1 of 11 compounds — the rest is available on a paid plan.

IMP Trials Status First start Last start
Adalimumab1Unknown2021-02-222021-02-22

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