Vseobecna Fakultni Nemocnice V Praze
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Nervous System Diseases
At Vseobecna Fakultni Nemocnice V Praze, clinical research in Nervous System Diseases focuses on conditions such as narcolepsy and generalized myasthenia gravis. The studies are designed to assess how new or adjusted treatments may improve symptom control, daily functioning, and related health outcomes for people living with these neurological disorders.
- Research on narcolepsy is examining whether changing treatment can help manage blood pressure and support safer long-term care.
- Studies in generalized myasthenia gravis are evaluating treatment effectiveness for improving everyday activities and disease control.
- The overall aim is to better understand how therapies may benefit patients with chronic neurological illness.
This work reflects a focused effort within the Neurologická klinika VFN a 1. LF UK to improve care for patients with sleep-related and neuromuscular conditions.
Immune System Diseases
Clinical trials in Immune System Diseases at this Prague site are centered on generalized myasthenia gravis, an autoimmune disorder that can weaken muscles and affect daily life. The research is aimed at testing whether targeted treatment can reduce symptoms and improve patient-reported functioning in people with active disease.
- Investigation of generalized myasthenia gravis is focused on symptom relief and better day-to-day performance.
- Researchers are comparing an active therapy with placebo to evaluate treatment benefit in seropositive patients.
- The studies support development of more effective care for autoimmune neuromuscular disease.
These trials add to the site’s broader interest in immune-related disorders and treatment response in real-world clinical settings.
Site Overview
Activity Indicator
Last 6 months
Trial Flow
How this site's trials are distributed across therapeutic areas and active substances (IMPs), and how they're positioned within their overall lifecycle status. Flow thickness represents the number of unique trials.
Compounds & Molecules Timeline
The time span of clinical-trial activity for the main active substances (IMPs) studied at this site over the last 8 years. Each bar runs from the earliest trial start to the most recent end; a substance with a trial still open has no recorded end and is shown as ongoing.
Sponsor & Partnership
Top sponsors by active trials, and the ones that have come back for more than one study.
Sponsor Network
Top 1 by active trials.
- 1Janssen Cilag International1active
Partnership History
Sponsors with repeated collaboration (≥ 2 trials).
No repeated partnerships found.
Sponsor Network Graph
How sponsors and therapeutic areas connect across this site's active trials: each link is at least one active trial shared between them, and bigger nodes mean more activity. Click a node to see its exact connections.
Country Benchmark
Compared to 634 other sites in Czechia
Therapeutic Area Benchmark — Czechia
Select a therapeutic area to compare against other sites in Czechia.
Competitor Comparison
Similar sites in the same country running a comparable number of trials (within ±30%), scored on how closely their trial portfolios match this one. Higher percentages mean a more similar profile.
Country: Czechia
Market Share
Country: Czechia
Therapeutic Area Market Share
Select a therapeutic area to view its disease coverage breakdown.
Heat Maps & Advanced Analytics
How often specific conditions appear in trials across this site and comparable sites from the same country. Each row is a site, each column a condition, and each cell the number of trials on it — darker means more activity.
Other Trials in Vseobecna Fakultni Nemocnice V Praze
lock Showing 1 of 2 trials — the rest is available on a paid plan.
| Trial | Sponsor | Phase | Status | Start Date | End Date |
|---|---|---|---|---|---|
| Evaluation of Blood Pressure Changes in Narcolepsy Patients Transitioning from High-Sodium Oxybate to JZP258 (Sodium, Calcium, Magnesium, Potassium Oxybate) | Jazz Pharmaceuticals PLC | Phase III | Not Recruiting | Jun 2024 | Mar 2025 |
IMP list
lock Showing 1 of 5 compounds — the rest is available on a paid plan.
| IMP | Trials | Status | First start | Last start |
|---|---|---|---|---|
| Calcium Oxybate | 1 | Unknown | 2024-06-14 | 2024-06-14 |
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