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Uniwersytecki Szpital Dzieciecy W Krakowie

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Inflammatory Bowel Disease and Pediatric Gastroenterology

At Uniwersytecki Szpital Dzieciecy W Krakowie, research in digestive system diseases focuses strongly on ulcerative colitis and Crohn’s disease in children and teenagers. These studies are designed to assess how well new and existing treatments control inflammation, support remission, and improve long-term disease management.

  • Testing biologic and oral therapies for moderate to severe ulcerative colitis and Crohn’s disease
  • Evaluating long-term safety and effectiveness of maintenance treatment in pediatric inflammatory bowel disease
  • Studying therapies aimed at reducing intestinal inflammation and improving clinical remission

This work reflects a major clinical focus on helping young patients with chronic gastrointestinal conditions achieve better symptom control and quality of life.

Pediatric Hematology and Leukemia

The site also has a major research presence in hemic and lymphatic diseases, especially acute lymphoblastic leukemia, acute myeloid leukemia, and lymphoblastic lymphoma. The trials are centered on improving survival, reducing relapse risk, and making treatment safer for children and adolescents.

  • Evaluating new treatment strategies for acute lymphoblastic leukemia and lymphoblastic lymphoma
  • Testing approaches to improve outcomes in acute myeloid leukemia, including high-risk and relapsed disease
  • Exploring ways to reduce treatment-related toxicity while preserving anti-cancer effectiveness

These studies support advanced pediatric cancer care through collaborative, disease-focused research at the hospital.

Neuroblastoma and Pediatric Solid Tumors

Clinical research in neoplasms includes important work on neuroblastoma and liver tumors such as hepatoblastoma and hepatocellular carcinoma. The goal is to improve outcomes for children with aggressive or hard-to-treat cancers through better treatment combinations and more effective disease control.

  • Assessing new immunotherapy and chemotherapy combinations for high-risk neuroblastoma
  • Studying treatment options for recurrent or resistant neuroblastoma
  • Investigating therapy strategies for pediatric liver cancers, including hepatoblastoma

These trials aim to strengthen treatment effectiveness while supporting safer care for young patients with complex solid tumors.

Kidney Disease, Anemia, and Metabolic Complications

Another key area at the Krakow pediatric hospital is nutritional and metabolic diseases and related kidney care, with studies in chronic kidney disease, anemia, proteinuric kidney disorders, and secondary hyperparathyroidism. Research here focuses on improving symptoms, correcting metabolic imbalances, and protecting kidney health in children.

  • Evaluating treatments for anemia in children and adolescents with chronic kidney disease
  • Studying therapies to reduce proteinuria in pediatric kidney disorders
  • Assessing treatment options for secondary hyperparathyroidism in dialysis patients

This work aims to improve day-to-day health and long-term outcomes for children living with chronic renal disease.

Immune Disorders, Transplantation, and Blood Conditions

The site conducts research in immune system diseases and related inflammatory processes, including chronic graft-versus-host disease, immune thrombocytopenia, and immune support with immunoglobulin therapy. These studies are intended to refine immune-based treatment and improve safety after intensive therapies.

  • Testing therapies for chronic graft-versus-host disease after transplantation
  • Evaluating treatment options for chronic idiopathic thrombocytopenic purpura
  • Studying immunoglobulin replacement to help prevent serious infections in children with immune deficiency

Through these investigations, the site contributes to better management of immune-related complications in pediatric care.

Rare Genetic and Metabolic Diseases

Research at Uniwersytecki Szpital Dzieciecy W Krakowie also includes congenital, hereditary, and neonatal diseases, with a focus on rare conditions such as Mucopolysaccharidosis type II and Hunter syndrome. These trials examine treatments aimed at easing disease burden and improving neurological and physical symptoms.

  • Evaluating therapies for MPS II and related inherited disorders
  • Studying effects on central nervous system and body-wide symptoms
  • Supporting long-term care research in rare pediatric metabolic disease

This area highlights the hospital’s role in advancing care for children with uncommon, lifelong conditions.

Pediatric Transplantation and Supportive Oncology Care

The hospital participates in research on hematopoietic stem cell transplantation and related supportive care, especially for children with acute lymphoblastic leukemia. These studies are designed to improve transplant outcomes, reduce complications, and maintain the anti-leukemia benefit of treatment.

  • Optimizing transplant strategies for children and adolescents with ALL
  • Assessing ways to lower treatment-related toxicity after HSCT
  • Exploring supportive approaches to prevent relapse and manage transplant complications

This research supports safer and more effective transplant-based care for young patients with high-risk blood cancers.

Site Overview

assignment
46
connected trials
corporate_fare
31
sponsors
science
102
IMPs

Activity Indicator

Last 6 months

1
Trials started
-83% vs previous period.
6
Trials started 6–12 months ago
46
Total trials linked
Highly Active
trending_downDeclining-83%
1
Mar
Apr
May
Jun
Jul
Aug

Trial Flow

How this site's trials are distributed across therapeutic areas and active substances (IMPs), and how they're positioned within their overall lifecycle status. Flow thickness represents the number of unique trials.

Therapeutic areaarrow_forwardIMParrow_forwardLifecycle status

Top 4 of 11 therapeutic areas and 15 of 102 IMPs, ranked by number of trials.

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Compounds & Molecules Timeline

The time span of clinical-trial activity for the main active substances (IMPs) studied at this site over the last 8 years. Each bar runs from the earliest trial start to the most recent end; a substance with a trial still open has no recorded end and is shown as ongoing.

Trial span Ongoing Showing last 8 years

Top 40 of 101 compounds, ranked by number of trials.

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Sponsor & Partnership

Top sponsors by active trials, and the ones that have come back for more than one study.

Active trials
27
Sponsors (total)
31
Active sponsors
20

Sponsor Network

Top 20 by active trials.

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Partnership History

Sponsors with repeated collaboration (≥ 2 trials).

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Sponsor Network Graph

How sponsors and therapeutic areas connect across this site's active trials: each link is at least one active trial shared between them, and bigger nodes mean more activity. Click a node to see its exact connections.

Country Benchmark

Compared to 1 624 other sites in Poland

description
Trial volume
46
Outperforms 94% of sites
public
Therapeutic diversity
11areas
Outperforms 96% of sites
groups
Sponsor diversity
31sponsors
Outperforms 95% of sites

Therapeutic Area Benchmark — Poland

Select a therapeutic area to compare against other sites in Poland.

Competitor Comparison

Similar sites in the same country running a comparable number of trials (within ±30%), scored on how closely their trial portfolios match this one. Higher percentages mean a more similar profile.

Country: Poland

Market Share

Country: Poland

Therapeutic Area Market Share

Select a therapeutic area to view its disease coverage breakdown.

Heat Maps & Advanced Analytics

How often specific conditions appear in trials across this site and comparable sites from the same country. Each row is a site, each column a condition, and each cell the number of trials on it — darker means more activity.

Other Trials in Uniwersytecki Szpital Dzieciecy W Krakowie

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Trial Sponsor Phase Status Start Date End Date
A Multicenter Randomized Non‑Inferiority Trial of Weekly Somatrogon versus Daily Somatropin in Pediatric Patients with Small‑for‑Gestational‑Age or Idiopathic Short StatureSchneider Children's Medical Center Of IsraelPhase IIINot Yet Recruiting

IMP list

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IMP Trials Status First start Last start
Etoposide10Unknown2017-10-022025-12-24

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