University Hospital Sveti Duh

At University Hospital Sveti Duh, the Department of Nephrology is involved in clinical studies focused on kidney diseases and related immune system diseases. The research includes efforts to better manage protein loss in urine, preserve kidney function, and improve treatment options for patients living with chronic renal conditions.

• Immunoglobulin A nephropathy and focal segmental glomerulosclerosis
• Studies assessing new therapies to reduce proteinuria and slow kidney damage
• Research on long-term safety and effectiveness of treatments for progressive renal disease

This activity highlights a strong focus on improving outcomes for people with glomerular diseases through better disease control and kidney protection.

The site is also participating in research across cardiovascular diseases, especially conditions such as atrial fibrillation, atherosclerotic cardiovascular disease, and different forms of heart failure. These trials aim to reduce serious events like stroke, heart attack, and worsening heart disease.

• Preventing stroke in patients with atrial fibrillation
• Lowering cardiovascular risk in atherosclerotic disease
• Evaluating treatments for acute and chronic heart failure

This cardiovascular research at University Hospital Sveti Duh reflects a broader effort to improve prevention and long-term management of major heart-related conditions.

Clinical trials in nervous system diseases are examining treatments for multiple sclerosis and different forms of epilepsy. The main goal is to improve control of relapses and seizures while also supporting safety and tolerability for patients.

• Multiple sclerosis with relapsing disease activity
• Idiopathic generalized epilepsy with generalized tonic-clonic seizures
• Refractory focal onset epilepsy

These studies are exploring whether newer therapies can offer better symptom control and more stable disease management for people with chronic neurological disorders.

Research in bacterial infections focuses on patients with serious infection risk, including those with blood cancers and hospitalized adults with complicated urinary infections. The studies aim to improve infection prevention and treatment effectiveness in difficult-to-manage settings.

• Preventing recurrent infections in patients with hematologic malignancies
• Treating complicated urinary tract infection and acute pyelonephritis
• Evaluating better options for infection control in vulnerable patients

This area of research supports safer and more effective care for patients facing infection-related complications.

The clinical trial portfolio also includes work in respiratory tract diseases and immune system diseases, with studies in asthma and Sjögren’s syndrome. These trials are designed to assess symptom relief, disease control, and the broader impact of treatment on daily life and systemic health.

• Moderate-to-severe uncontrolled asthma
• Sjögren’s syndrome with systemic disease activity
• Sjögren’s syndrome with persistent symptom burden

The research reflects interest in both inflammatory airway disease and autoimmune conditions that affect multiple organs.

Additional studies at University Hospital Sveti Duh cover a wide range of specialties, including eye diseases, musculoskeletal diseases, and other chronic conditions. These trials are aimed at testing new treatment approaches and improving functional outcomes for patients.

• Neovascular age-related macular degeneration and visual preservation
• Patellofemoral osteoarthritis and joint function
• Broader studies in cardiovascular and pathological conditions

Together, these studies show a diverse research environment that combines disease-specific treatment evaluation with efforts to improve long-term quality of life.