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Universitaetsklinikum Knappschaftskrankenhaus Bochum GmbH

Address
In Der Schornau 23-25, Langendreer, 44892 Bochum, Germany

Universitaetsklinikum Knappschaftskrankenhaus Bochum GmbH - Comprehensive Oncology and Critical Care Research Center

The Universitaetsklinikum Knappschaftskrankenhaus Bochum GmbH stands as a leading academic medical center with extensive expertise in hematologic malignancies and neuro-oncology. The center demonstrates particular strength in conducting complex phase III trials for newly diagnosed cancers, with a focus on innovative therapeutic combinations and personalized medicine approaches. Their research portfolio encompasses a broad spectrum of adult oncology, including advanced trials in acute leukemias, lymphomas, and brain tumors, as well as critical care interventions.

  • Acute Myeloid Leukemia (AML) and Myelodysplastic Syndromes - Multiple phase III trials evaluating novel agents including venetoclax, CPX-351, IDH inhibitors, and FLT3-targeted therapies in combination with chemotherapy
  • Brain Tumor Research - Comprehensive glioma studies including glioblastoma, WHO grade 2/3 gliomas with 1p/19q co-deletion, and primary CNS lymphoma trials
  • Lymphoma Therapeutics - Advanced Hodgkin lymphoma, aggressive B-cell lymphoma, and Philadelphia-positive acute lymphoblastic leukemia trials
  • Solid Tumor Oncology and Critical Care - Investigations in hepatocellular carcinoma, rectal cancer, gastroesophageal adenocarcinoma, and sepsis management

The center's research approach emphasizes comparative effectiveness studies and treatment optimization, with particular attention to elderly patient populations and those ineligible for intensive chemotherapy. Their involvement in multiple myeloma maintenance strategies, transplant rejection prophylaxis in kidney transplant recipients, and novel immunotherapy combinations demonstrates a commitment to improving outcomes across diverse patient populations. The facility also conducts important metabolic disease research, including trials for non-alcoholic steatohepatitis (NASH) and alcohol-related liver disease, alongside innovative critical care studies evaluating sedation strategies and adjunctive therapies for septic shock.

Site Overview

assignment
30
connected trials
corporate_fare
20
sponsors
science
70
IMPs

Activity Indicator

Last 6 months

1
Trials started
-67% vs previous period.
3
Trials started 6–12 months ago
30
Total trials linked
Highly Active
trending_downDeclining-67%
1
Mar
Apr
May
Jun
Jul
Aug

Trial Flow

How this site's trials are distributed across therapeutic areas and active substances (IMPs), and how they're positioned within their overall lifecycle status. Flow thickness represents the number of unique trials.

Therapeutic areaarrow_forwardIMParrow_forwardLifecycle status

Top 3 of 7 therapeutic areas and 15 of 70 IMPs, ranked by number of trials.

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Compounds & Molecules Timeline

The time span of clinical-trial activity for the main active substances (IMPs) studied at this site over the last 8 years. Each bar runs from the earliest trial start to the most recent end; a substance with a trial still open has no recorded end and is shown as ongoing.

Trial span Ongoing Showing last 8 years

Top 40 of 70 compounds, ranked by number of trials.

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Sponsor & Partnership

Top sponsors by active trials, and the ones that have come back for more than one study.

Active trials
19
Sponsors (total)
20
Active sponsors
16

Sponsor Network

Top 16 by active trials.

Partnership History

Sponsors with repeated collaboration (≥ 2 trials).

Sponsor Network Graph

How sponsors and therapeutic areas connect across this site's active trials: each link is at least one active trial shared between them, and bigger nodes mean more activity. Click a node to see its exact connections.

Country Benchmark

Compared to 2 161 other sites in Germany

description
Trial volume
30
Outperforms 93% of sites
public
Therapeutic diversity
10areas
Outperforms 96% of sites
groups
Sponsor diversity
20sponsors
Outperforms 93% of sites

Therapeutic Area Benchmark — Germany

Select a therapeutic area to compare against other sites in Germany.

Competitor Comparison

Similar sites in the same country running a comparable number of trials (within ±30%), scored on how closely their trial portfolios match this one. Higher percentages mean a more similar profile.

Country: Germany

Market Share

Country: Germany

Therapeutic Area Market Share

Select a therapeutic area to view its disease coverage breakdown.

Heat Maps & Advanced Analytics

How often specific conditions appear in trials across this site and comparable sites from the same country. Each row is a site, each column a condition, and each cell the number of trials on it — darker means more activity.

Other Trials in Universitaetsklinikum Knappschaftskrankenhaus Bochum GmbH

lock Showing 1 of 30 trials — the rest is available on a paid plan.

Trial Sponsor Phase Status Start Date End Date
Cholangiocarcinoma treatment with radiofrequency ablation or photodynamic therapyUniversitaet LeipzigPhase IIIRecruitingOct 2022

IMP list

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IMP Trials Status First start Last start
Cytarabine4Unknown2019-08-282025-12-19

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