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Universita' Politecnica Delle Marche

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Immune System Diseases and Musculoskeletal Diseases

At Universita' Politecnica Delle Marche, clinical research in this area focuses on the overlap between immune system disorders and muscle-related conditions, with particular attention to polymyositis and dermatomyositis. The studies are designed to better understand disease activity and assess whether new treatment approaches can improve patient outcomes.

  • Exploring treatment options for idiopathic inflammatory myopathies
  • Evaluating the impact of anifrolumab compared with placebo alongside standard care
  • Assessing improvement in disease activity for adults with polymyositis and dermatomyositis

This work reflects a focused effort in clinical immunology and rheumatology, aiming to support more effective care for people living with these rare inflammatory diseases.

Immune System Phenomena and Musculoskeletal and Neural Physiological Phenomena

The research portfolio also examines key immune system processes and their effects on muscle function and related physiological changes. Conducted at the Department of Molecular and Clinical Sciences, these trials contribute to a better understanding of how inflammation influences disease progression and treatment response.

  • Studying immune-mediated inflammation in inflammatory myopathies
  • Investigating how therapy may improve musculoskeletal symptoms
  • Supporting research into more precise disease control for affected adults

With a small but targeted trial base and broad investigator involvement, the site is building knowledge around autoimmune muscle disease and practical ways to measure treatment benefit.

Site Overview

assignment
310
connected trials
corporate_fare
150
sponsors
science
430
IMPs

Activity Indicator

Last 6 months

26
Trials started
-4% vs previous period.
27
Trials started 6–12 months ago
310
Total trials linked
Highly Active
trending_downDeclining-4%
7
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4
5
5
3
Mar
Apr
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Trial Flow

How this site's trials are distributed across therapeutic areas and active substances (IMPs), and how they're positioned within their overall lifecycle status. Flow thickness represents the number of unique trials.

Therapeutic areaarrow_forwardIMParrow_forwardLifecycle status

Top 3 of 24 therapeutic areas and 15 of 430 IMPs, ranked by number of trials.

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Compounds & Molecules Timeline

The time span of clinical-trial activity for the main active substances (IMPs) studied at this site over the last 8 years. Each bar runs from the earliest trial start to the most recent end; a substance with a trial still open has no recorded end and is shown as ongoing.

Trial span Ongoing Showing last 8 years

Top 40 of 417 compounds, ranked by number of trials.

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Sponsor & Partnership

Top sponsors by active trials, and the ones that have come back for more than one study.

Active trials
158
Sponsors (total)
150
Active sponsors
98

Sponsor Network

Top 98 by active trials.

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Partnership History

Sponsors with repeated collaboration (≥ 2 trials).

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Sponsor Network Graph

How sponsors and therapeutic areas connect across this site's active trials: each link is at least one active trial shared between them, and bigger nodes mean more activity. Click a node to see its exact connections.

Country Benchmark

Compared to 566 other sites in Italy

description
Trial volume
310
Outperforms 96% of sites
public
Therapeutic diversity
24areas
Outperforms 95% of sites
groups
Sponsor diversity
150sponsors
Outperforms 97% of sites

Therapeutic Area Benchmark — Italy

Select a therapeutic area to compare against other sites in Italy.

Competitor Comparison

Similar sites in the same country running a comparable number of trials (within ±30%), scored on how closely their trial portfolios match this one. Higher percentages mean a more similar profile.

Country: Italy

Market Share

Country: Italy

Therapeutic Area Market Share

Select a therapeutic area to view its disease coverage breakdown.

Heat Maps & Advanced Analytics

How often specific conditions appear in trials across this site and comparable sites from the same country. Each row is a site, each column a condition, and each cell the number of trials on it — darker means more activity.

Other Trials in Universita' Politecnica Delle Marche

lock Showing 1 of 310 trials — the rest is available on a paid plan.

Trial Sponsor Phase Status Start Date End Date
(22153) Randomized, Double-Masked, Active-Controlled, Phase 3 Study of the Efficacy and Safety of Aflibercept 8 mg in Macular Edema Secondary to Retinal Vein OcclusionBayer AGPhase IIINot RecruitingSep 2023May 2025

IMP list

lock Showing 1 of 430 compounds — the rest is available on a paid plan.

IMP Trials Status First start Last start
Dexamethasone16Unknown2017-10-022025-09-30

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