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Universita' Di Pisa

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Congenital, Hereditary, and Neonatal Diseases

At Universita' Di Pisa, research in congenital and hereditary diseases focuses on children and patients with serious rare conditions, especially high-risk neuroblastoma and primary mitochondrial disease. The trials are designed to test new treatment strategies, refine disease monitoring, and better understand treatment response in complex inherited disorders.

  • Evaluating treatment strategies for high-risk neuroblastoma to improve long-term disease control
  • Studying primary mitochondrial disease to assess safety, tolerability, and biological response to therapy
  • Improving outcomes in rare pediatric and inherited conditions through more effective treatment approaches

This area brings together pediatric oncology and rare disease research, with a strong emphasis on finding better options for patients with limited treatment choices.

Immune System Diseases

Clinical research in immune system diseases at this site includes work on primary Sjogren's syndrome, with studies aimed at identifying better ways to measure response and improve treatment effectiveness. The goal is to support more personalized care for patients living with chronic autoimmune disease.

  • Investigating primary Sjogren's syndrome to improve clinical endpoints and assess how well treatments work
  • Exploring combinations of existing therapies to strengthen symptom control in autoimmune disease
  • Advancing rheumatology research through better evaluation of patient response

The Department of Maternal and Child Health contributes to research that aims to make autoimmune treatment assessment more accurate and clinically meaningful.

Musculoskeletal Diseases

Research in musculoskeletal diseases at Universita' Di Pisa includes studies in primary mitochondrial disease, particularly for patients affected by myopathy and cardiomyopathy. These trials are focused on understanding safety, tolerability, and whether treatment can improve key disease-related symptoms.

  • Assessing therapies for myopathy linked to rare metabolic and hereditary disorders
  • Monitoring treatment effects in cardiomyopathy associated with mitochondrial disease
  • Supporting better management of muscle and movement-related complications in rare disease care

This work connects neuromuscular research with broader efforts to improve quality of life in patients with chronic, disabling conditions.

Neoplasms

The neoplasm research portfolio at this site is centered on prostate cancer and high-risk neuroblastoma. The trials are designed to evaluate treatment effectiveness, track longer-term safety, and test new combinations or strategies for patients with difficult-to-treat cancers.

  • Studying prostate cancer to gather long-term safety information after prior treatment
  • Testing more effective approaches for high-risk neuroblastoma, including improved disease control after initial therapy
  • Exploring oncology strategies that may strengthen response in patients with residual or metastatic disease

Cancer research at Universita' Di Pisa combines pediatric oncology and adult oncology interests, with a focus on improving outcomes in aggressive and advanced disease.

Site Overview

assignment
9
connected trials
corporate_fare
9
sponsors
science
28
IMPs

Activity Indicator

Last 6 months

1
Trials started
New activity detected vs previous period.
0
Trials started 6–12 months ago
9
Total trials linked
Active
trending_upGrowing+100%
1
Mar
Apr
May
Jun
Jul
Aug

Trial Flow

How this site's trials are distributed across therapeutic areas and active substances (IMPs), and how they're positioned within their overall lifecycle status. Flow thickness represents the number of unique trials.

Therapeutic areaarrow_forwardIMParrow_forwardLifecycle status

Top 4 of 5 therapeutic areas and 15 of 28 IMPs, ranked by number of trials.

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Compounds & Molecules Timeline

The time span of clinical-trial activity for the main active substances (IMPs) studied at this site over the last 8 years. Each bar runs from the earliest trial start to the most recent end; a substance with a trial still open has no recorded end and is shown as ongoing.

Trial span Ongoing Showing last 8 years
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Sponsor & Partnership

Top sponsors by active trials, and the ones that have come back for more than one study.

Active trials
7
Sponsors (total)
9
Active sponsors
7

Sponsor Network

Top 7 by active trials.

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Partnership History

Sponsors with repeated collaboration (≥ 2 trials).

No repeated partnerships found.

Sponsor Network Graph

How sponsors and therapeutic areas connect across this site's active trials: each link is at least one active trial shared between them, and bigger nodes mean more activity. Click a node to see its exact connections.

Country Benchmark

Compared to 566 other sites in Italy

description
Trial volume
9
Outperforms 67% of sites
public
Therapeutic diversity
6areas
Outperforms 75% of sites
groups
Sponsor diversity
9sponsors
Outperforms 69% of sites

Therapeutic Area Benchmark — Italy

Select a therapeutic area to compare against other sites in Italy.

Competitor Comparison

Similar sites in the same country running a comparable number of trials (within ±30%), scored on how closely their trial portfolios match this one. Higher percentages mean a more similar profile.

Country: Italy

Market Share

Country: Italy

Therapeutic Area Market Share

Select a therapeutic area to view its disease coverage breakdown.

Heat Maps & Advanced Analytics

How often specific conditions appear in trials across this site and comparable sites from the same country. Each row is a site, each column a condition, and each cell the number of trials on it — darker means more activity.

Other Trials in Universita' Di Pisa

lock Showing 1 of 9 trials — the rest is available on a paid plan.

Trial Sponsor Phase Status Start Date End Date
An 18-month low-interventional prospective, multicentre study to assess joint outcomes in patients with haemophilia A or B on prophylaxis with efmoroctocog alfa or eftrenonacog alfaSwedish Orphan Biovitrum AB (publ)Phase IIINot Yet RecruitingJul 2023Dec 2023

IMP list

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IMP Trials Status First start Last start
Carboplatin2Unknown2024-11-212025-01-09

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