Unidade Local De Saude De Tras-Os-Montes E Alto Douro E.P.E.
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Cardiovascular Diseases
The Unidade Local De Saude De Tras-Os-Montes E Alto Douro E.P.E. is involved in cardiovascular research focused on major conditions such as acute coronary syndrome, atherosclerotic cardiovascular disease, and chronic heart failure. These studies are designed to test new treatments and prevention strategies that may reduce serious heart-related events and improve long-term outcomes.
- Evaluating therapies aimed at lowering the risk of heart attack, stroke, and other major cardiovascular events
- Studying treatment options for symptomatic heart failure and related complications
- Exploring approaches for transthyretin amyloidosis with cardiac involvement
Overall, this research area combines prevention, symptom control, and outcome improvement across several important heart and vascular diseases.
Neoplasms
In medical oncology, the site is running trials across a broad range of cancers, including advanced breast cancer, gastric and gastroesophageal cancer, colorectal cancer, head and neck squamous cell carcinoma, and multiple myeloma. The main goal is to assess new cancer treatments and compare them with current standards of care.
- Testing novel therapies for HER2-positive and HER2-low breast cancer
- Evaluating treatment strategies for metastatic gastric and gastroesophageal junction cancer
- Studying options for metastatic colorectal cancer and head and neck cancer
These studies reflect a strong focus on improving survival, disease control, and treatment selection for patients with difficult-to-treat solid tumors and blood cancers.
Digestive System Diseases
Research in digestive system diseases at this site centers on liver and biliary disorders, especially non-alcoholic steatohepatitis, primary biliary cholangitis, and locoregional hepatocellular carcinoma. The trials are aimed at improving disease control, slowing progression, and reducing the risk of serious liver-related complications.
- Assessing treatments that may improve liver histology and reduce fibrosis
- Studying therapies for primary biliary cholangitis and cirrhosis-related outcomes
- Testing combined treatment approaches for hepatocellular carcinoma
This line of research supports better care for patients with chronic liver disease and cancer affecting the digestive system.
Nervous System Diseases
The site also contributes to neurology research, with studies in focal onset seizures and primary generalized tonic-clonic seizures. These trials are designed to assess whether new therapies can better reduce seizure frequency and support longer-term seizure management.
- Evaluating medicines for better seizure control
- Investigating longer-term treatment safety and tolerability in epilepsy
- Improving quality of life for people living with recurring seizure disorders
This area reflects a practical focus on finding more effective and better-tolerated options for patients with chronic neurological conditions.
Nutritional and Metabolic Diseases
Within nutritional and metabolic diseases, the trials at this hospital address conditions such as non-alcoholic steatohepatitis and related metabolic liver problems. The research is centered on testing therapies that may improve disease activity and prevent progression to more advanced illness.
- Studying treatments for metabolic liver disease and fibrosis
- Assessing whether new therapies can reduce liver-related clinical events
- Supporting better management of chronic conditions linked to metabolism and liver health
These studies aim to address both the underlying disease process and the long-term complications associated with metabolic dysfunction.
Other Research Areas
Some trials at Unidade Local De Saude De Tras-Os-Montes E Alto Douro E.P.E. span multiple therapeutic areas or do not fit neatly into a single category. These studies often focus on broader questions of treatment effectiveness, safety, and clinical benefit across complex diseases.
- Comparing treatment strategies to identify the most effective care pathways
- Evaluating supportive approaches that may help patients stay on planned cancer therapy
- Assessing new options for diseases with overlapping cardiovascular, oncology, and metabolic features
This diverse portfolio shows a wide-ranging commitment to clinical research across several major medical specialties.
Site Overview
Activity Indicator
Last 6 months
Trial Flow
How this site's trials are distributed across therapeutic areas and active substances (IMPs), and how they're positioned within their overall lifecycle status. Flow thickness represents the number of unique trials.
Top 3 of 6 therapeutic areas and 15 of 53 IMPs, ranked by number of trials.
Compounds & Molecules Timeline
The time span of clinical-trial activity for the main active substances (IMPs) studied at this site over the last 8 years. Each bar runs from the earliest trial start to the most recent end; a substance with a trial still open has no recorded end and is shown as ongoing.
Top 40 of 50 compounds, ranked by number of trials.
Sponsor & Partnership
Top sponsors by active trials, and the ones that have come back for more than one study.
Sponsor Network
Top 15 by active trials.
- 1Xenon Pharmaceuticals Inc.2active
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Partnership History
Sponsors with repeated collaboration (≥ 2 trials).
- 1Xenon Pharmaceuticals Inc.2trials
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Sponsor Network Graph
How sponsors and therapeutic areas connect across this site's active trials: each link is at least one active trial shared between them, and bigger nodes mean more activity. Click a node to see its exact connections.
Country Benchmark
Compared to 84 other sites in Portugal
Therapeutic Area Benchmark — Portugal
Select a therapeutic area to compare against other sites in Portugal.
Competitor Comparison
Similar sites in the same country running a comparable number of trials (within ±30%), scored on how closely their trial portfolios match this one. Higher percentages mean a more similar profile.
Country: Portugal
Market Share
Country: Portugal
Therapeutic Area Market Share
Select a therapeutic area to view its disease coverage breakdown.
Heat Maps & Advanced Analytics
How often specific conditions appear in trials across this site and comparable sites from the same country. Each row is a site, each column a condition, and each cell the number of trials on it — darker means more activity.
Other Trials in Unidade Local De Saude De Tras-Os-Montes E Alto Douro E.P.E.
lock Showing 1 of 25 trials — the rest is available on a paid plan.
| Trial | Sponsor | Phase | Status | Start Date | End Date |
|---|---|---|---|---|---|
| A Multicenter, Open-label, Long-term, Safety, Tolerability, and Efficacy Study of XEN1101 in Subjects Diagnosed With Epilepsy (X-TOLE4) | Xenon Pharmaceuticals Inc. | Phase III | Recruiting | Feb 2024 | — |
IMP list
lock Showing 1 of 53 compounds — the rest is available on a paid plan.
| IMP | Trials | Status | First start | Last start |
|---|---|---|---|---|
| Letrozole | 4 | Unknown | 2025-03-24 | 2026-02-24 |
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