Unidade Local De Saude De Loures-Odivelas EPE

The Medical Oncology team at Unidade Local De Saude De Loures-Odivelas EPE is actively involved in studies for neoplasms, with a strong focus on breast cancer and non-small cell lung cancer. These trials are designed to test new treatment approaches and compare them with current standards to improve disease control and survival.

• Advanced and metastatic breast cancer, including HER2-positive, HER2-negative, and hormone receptor-positive disease
• Evaluating new therapies and treatment combinations to improve progression-free survival and overall outcomes
• Research in early and advanced-stage disease, including patients at high risk of recurrence

These studies reflect a broad effort to refine cancer care through more effective and better-targeted treatment options.

Research in respiratory tract diseases and neoplasms includes trials in non-small cell lung cancer, lung cancer, idiopathic pulmonary fibrosis, and progressive pulmonary fibrosis. The main goal is to evaluate new therapies that may slow disease progression, improve breathing-related outcomes, and extend survival.

• Non-small cell lung cancer, including locally advanced, metastatic, and EGFR-mutated disease
• Idiopathic pulmonary fibrosis and progressive pulmonary fibrosis, focusing on lung function and disease stabilization
• Testing novel treatment combinations and supportive approaches for difficult-to-treat respiratory conditions

This area highlights the site’s interest in both cancer and chronic lung disease research, with studies aimed at improving treatment effectiveness.

The site also contributes to studies in digestive system diseases and immune system diseases, especially Crohn's disease, ulcerative colitis, and eosinophilic esophagitis. These trials are intended to assess whether new therapies can reduce inflammation, control symptoms, and support long-term remission.

• Crohn's disease and ulcerative colitis in moderate to severe forms
• Eosinophilic esophagitis, with a focus on improving swallowing-related inflammation
• Evaluating maintenance strategies and long-term disease control

At Unidade Local De Saude De Loures-Odivelas EPE, this research area supports more personalized care for chronic inflammatory bowel conditions.

Clinical trials in cardiovascular diseases and kidney-related conditions are examining chronic kidney disease, focal segmental glomerulosclerosis, atherosclerotic cardiovascular disease, and hypertension. The focus is on protecting organ function, reducing inflammation, and lowering the risk of major cardiovascular events.

• Chronic kidney disease and focal segmental glomerulosclerosis, with attention to kidney function preservation
• Hypertension and high cardiovascular risk, aiming to reduce serious heart and stroke outcomes
• Studying therapies that may improve both kidney and heart health

These studies show a strong interest in chronic disease prevention and long-term risk reduction.

Research in nervous system diseases includes studies in acute ischemic stroke, primary progressive multiple sclerosis, multiple system atrophy, and upper limb spasticity after stroke or traumatic brain injury. The purpose of these trials is to improve recovery, slow neurological decline, and address disabling symptoms.

• Acute ischemic stroke, focusing on better functional recovery after the event
• Primary progressive multiple sclerosis, aiming to delay worsening disability
• Upper limb spasticity, evaluating options to reduce muscle stiffness and improve movement

This field brings together acute care and chronic neurological disease management in a way that may benefit patients with very different needs.

The site participates in trials across respiratory tract diseases, otorhinolaryngologic diseases, and immune system diseases, including chronic rhinosinusitis with nasal polyps, chronic obstructive pulmonary disease, and alpha-1 antitrypsin deficiency. These studies are designed to improve symptom control and support better day-to-day breathing and quality of life.

• Chronic rhinosinusitis with nasal polyps, with a focus on reducing congestion and polyp burden
• Chronic obstructive pulmonary disease and alpha-1 antitrypsin deficiency, exploring new ways to manage chronic lung disease
• Testing therapies aimed at improving respiratory comfort and long-term disease control

This area shows a practical focus on chronic airway conditions that can significantly affect everyday functioning.

Clinical research at the site also covers mental disorders and other quality-of-life conditions such as major depressive disorder with insomnia symptoms and menstrual migraine. The aim is to evaluate treatments that may relieve symptoms, improve sleep, and reduce the burden of recurrent headaches and mood disorders.

• Major depressive disorder with insomnia symptoms, studying add-on treatment approaches
• Menstrual migraine, focusing on prevention of migraine attacks
• Assessing whether new therapies can improve daily functioning and symptom relief

These studies expand the site’s portfolio beyond oncology and internal medicine into conditions that affect both mental and physical well-being.

There is also activity in eye diseases, including polypoidal choroidal vasculopathy. The research is intended to determine whether new treatment options can improve vision and help preserve eye health in patients with symptomatic retinal disease.

• Polypoidal choroidal vasculopathy, a retinal condition that can affect central vision
• Evaluating therapies aimed at improving visual outcomes
• Supporting research into better management of chronic eye disease

This smaller but important area reflects the site’s wider interest in specialized, patient-centered clinical research.