Tartu University Hospital

The Cancer Centre is involved in clinical research on advanced tumors and glioblastoma multiforme, focusing on neoplasms and new ways to improve patient outcomes.

• Testing new treatment approaches for newly diagnosed glioblastoma
• Evaluating whether adding novel therapy to standard care can improve survival in advanced cancer
• Studying overall survival and treatment effectiveness in aggressive brain tumors

This work reflects a strong interest in finding better options for difficult-to-treat cancers, especially where current therapies may have limited benefit.

Research at the site includes immune system diseases such as moderate and severe atopic dermatitis, with studies designed to assess how well new therapies control symptoms and improve quality of life.

• Assessing the safety and effectiveness of targeted treatment for atopic dermatitis
• Exploring better symptom control in patients who need systemic therapy
• Supporting improved care for chronic inflammatory skin disease

The focus is on helping patients with persistent eczema-like inflammation by testing therapies that may offer stronger and more consistent relief.

Clinical trials in otorhinolaryngologic diseases are addressing chronic rhinosinusitis with nasal polyps, aiming to reduce inflammation and improve nasal symptoms in people with long-term sinus disease.

• Testing a new biologic approach for CRSwNP
• Measuring changes in nasal polyp burden and symptom scores
• Improving treatment options for patients with non-type 2 sinus inflammation

This area of research is centered on finding more effective ways to manage a condition that can significantly affect breathing, smell, and daily comfort.

The site is also studying cardiovascular diseases, particularly heart failure with mildly reduced ejection fraction and heart failure with preserved ejection fraction linked to systemic inflammation.

• Evaluating whether a new anti-inflammatory therapy can lower cardiovascular risk
• Studying prevention of heart failure events and cardiovascular death
• Improving treatment strategies for patients with inflammatory heart disease

These trials aim to refine care for people living with complex forms of heart failure, where inflammation may play an important role in disease progression.

Research in bacterial infections includes studies of nosocomial infection and pneumonia, with a focus on improving the safety and tolerability of antibacterial treatment.

• Assessing treatment options for hospital-acquired pneumonia
• Evaluating safety in patients with serious bacterial infections
• Supporting better infection control and treatment in vulnerable patients

This work helps inform more effective antibiotic use for infections that can be especially challenging in hospital settings.

The trial portfolio also covers virus diseases, including research involving healthy individuals and people with stable conditions that raise the risk of influenza complications.

• Studying immune responses to influenza vaccination
• Comparing vaccine performance across different formulations
• Improving protection for older adults and higher-risk groups

This research supports better prevention strategies against seasonal flu by examining how well vaccines stimulate immunity in important patient groups.