Summit Clinical Research s.r.o.
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Digestive and Metabolic Research
At Summit Clinical Research s.r.o. in Slovakia, clinical trials in digestive system diseases and nutritional and metabolic diseases are focused on hepatic impairment. This work helps evaluate how liver problems may affect the way new therapies behave in the body and supports safer treatment use for people with reduced liver function.
- Studies involving people with hepatic impairment, including moderate and severe forms
- Research on digestive system diseases linked to liver function and metabolism
- Assessment of how liver conditions influence the performance of new treatments
The site’s research in this area is aimed at improving understanding of treatment safety, tolerability, and effectiveness in patients with liver-related disease.
Pharmacology and Liver Function Studies
The department of internal medicine and clinical pharmacology conducts trials that examine the impact of hepatic impairment on how investigational therapies are processed by the body. These studies are designed to support better dosing guidance and more informed use of new medicines in patients with liver disease.
- Evaluation of pharmacokinetics in people with varying degrees of liver impairment
- Testing the safety and tolerability of new therapies in liver-compromised participants
- Research to understand treatment behavior in moderate or severe hepatic impairment
This area reflects a strong focus on clinical pharmacology questions that help bridge laboratory findings with practical patient care.
Liver-Related Therapeutic Research
Clinical research at Summit Clinical Research s.r.o. also includes studies of therapies for people with and without liver problems, with attention to how hepatic impairment may change treatment response. The trials are intended to support the development of new therapies and improve the evidence base for use in patients with compromised liver function.
- Investigation of new therapies in participants with and without liver problems
- Studies assessing the effect of hepatic impairment on treatment handling by the body
- Clinical evaluation of safety, tolerability, and treatment behavior in liver disease
With a small but focused portfolio, the site contributes to research that may help make future treatments more suitable for patients affected by liver-related conditions.
Site Overview
Activity Indicator
Last 6 months
Trial Flow
How this site's trials are distributed across therapeutic areas and active substances (IMPs), and how they're positioned within their overall lifecycle status. Flow thickness represents the number of unique trials.
Compounds & Molecules Timeline
The time span of clinical-trial activity for the main active substances (IMPs) studied at this site over the last 8 years. Each bar runs from the earliest trial start to the most recent end; a substance with a trial still open has no recorded end and is shown as ongoing.
Sponsor & Partnership
Top sponsors by active trials, and the ones that have come back for more than one study.
Sponsor Network
Top 4 by active trials.
- 1Taiho Oncology Inc.3active
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Partnership History
Sponsors with repeated collaboration (≥ 2 trials).
- 1Taiho Oncology Inc.3trials
Sponsor Network Graph
How sponsors and therapeutic areas connect across this site's active trials: each link is at least one active trial shared between them, and bigger nodes mean more activity. Click a node to see its exact connections.
Country Benchmark
Compared to 353 other sites in Slovakia
Therapeutic Area Benchmark — Slovakia
Select a therapeutic area to compare against other sites in Slovakia.
Competitor Comparison
Similar sites in the same country running a comparable number of trials (within ±30%), scored on how closely their trial portfolios match this one. Higher percentages mean a more similar profile.
Country: Slovakia
Market Share
Country: Slovakia
Therapeutic Area Market Share
Select a therapeutic area to view its disease coverage breakdown.
Heat Maps & Advanced Analytics
How often specific conditions appear in trials across this site and comparable sites from the same country. Each row is a site, each column a condition, and each cell the number of trials on it — darker means more activity.
Other Trials in Summit Clinical Research s.r.o.
lock Showing 1 of 11 trials — the rest is available on a paid plan.
| Trial | Sponsor | Phase | Status | Start Date | End Date |
|---|---|---|---|---|---|
| A Phase 1 Study to Evaluate the Pharmacokinetics and Safety of NNC0487 in Subjects with Hepatic Impairment and Normal Hepatic Function | Novo Nordisk A/S | Phase I | Recruiting | May 2026 | — |
IMP list
lock Showing 1 of 2 compounds — the rest is available on a paid plan.
| IMP | Trials | Status | First start | Last start |
|---|---|---|---|---|
| Cedazuridine | 1 | Unknown | 2022-03-17 | 2022-03-17 |
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