Stichting Radboud University Medical Center
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Musculoskeletal Diseases and Bacterial Infections
At Stichting Radboud University Medical Center in Nijmegen, the orthopedics research program includes studies focused on prosthetic joint infection, a serious complication affecting joint replacement patients. This work sits at the intersection of musculoskeletal care and infection management, with trials designed to compare treatment strategies and improve how infected implants are managed.
- Evaluating whether targeted antibiotic treatment can work as well as standard combination therapy for infected joint prostheses
- Improving treatment choices for patients with staphylococcal prosthetic joint infection
- Supporting better outcomes in orthopedic infection care
The research aims to refine antibiotic therapy for joint infections and help identify effective, practical options for patients recovering from implant-related infection.
Neoplasms and Diagnostic/Therapeutic Techniques
This site is also studying non-medullary thyroid carcinoma, especially cases with locally advanced or metastatic disease where standard radioiodine handling is limited. The trials explore ways to improve radioiodine uptake and strengthen treatment response in patients with harder-to-treat thyroid cancer.
- Testing whether digoxin can help restore radioiodine uptake in advanced thyroid cancer
- Exploring new approaches for patients with insufficient response to radioiodine-based treatment
- Advancing care for locally advanced and metastatic thyroid malignancies
These studies focus on finding a better therapeutic approach for thyroid cancer when conventional treatment is not enough.
Anesthesia and Analgesia in Critically Ill Patients
The clinical research portfolio at Stichting Radboud University Medical Center also includes work in critical care, examining older ventilated patients who depend on intensive medical support. The main goal is to assess whether early use of dexmedetomidine can improve outcomes compared with usual sedation practice.
- Studying mortality in older critically ill patients receiving early sedative treatment
- Evaluating sedation strategies for mechanically ventilated patients
- Building evidence for safer and more effective critical care sedation
This research supports better decision-making in anesthesia and analgesia for patients requiring intensive support, with a focus on treatment effectiveness and patient survival.
Site Overview
Activity Indicator
Last 6 months
Trial Flow
How this site's trials are distributed across therapeutic areas and active substances (IMPs), and how they're positioned within their overall lifecycle status. Flow thickness represents the number of unique trials.
Compounds & Molecules Timeline
The time span of clinical-trial activity for the main active substances (IMPs) studied at this site over the last 8 years. Each bar runs from the earliest trial start to the most recent end; a substance with a trial still open has no recorded end and is shown as ongoing.
Sponsor & Partnership
Top sponsors by active trials, and the ones that have come back for more than one study.
Sponsor Network
Top 2 by active trials.
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Partnership History
Sponsors with repeated collaboration (≥ 2 trials).
No repeated partnerships found.
Sponsor Network Graph
How sponsors and therapeutic areas connect across this site's active trials: each link is at least one active trial shared between them, and bigger nodes mean more activity. Click a node to see its exact connections.
Country Benchmark
Compared to 271 other sites in The Netherlands
Therapeutic Area Benchmark — The Netherlands
Select a therapeutic area to compare against other sites in The Netherlands.
Competitor Comparison
Similar sites in the same country running a comparable number of trials (within ±30%), scored on how closely their trial portfolios match this one. Higher percentages mean a more similar profile.
Country: The Netherlands
Market Share
Country: The Netherlands
Therapeutic Area Market Share
Select a therapeutic area to view its disease coverage breakdown.
Heat Maps & Advanced Analytics
How often specific conditions appear in trials across this site and comparable sites from the same country. Each row is a site, each column a condition, and each cell the number of trials on it — darker means more activity.
Other Trials in Stichting Radboud University Medical Center
lock Showing 1 of 3 trials — the rest is available on a paid plan.
| Trial | Sponsor | Phase | Status | Start Date | End Date |
|---|---|---|---|---|---|
| Digoxin for the Reinduction or Radioiodine Uptake in Metastatic or Locally Advanced Non-medullary Thyroid Carcinoma. | Radboud universitair medisch centrum Stichting | Phase II | Not Recruiting | Nov 2022 | Jun 2023 |
IMP list
lock Showing 1 of 11 compounds — the rest is available on a paid plan.
| IMP | Trials | Status | First start | Last start |
|---|---|---|---|---|
| Ciprofloxacin Hydrochloride Monohydrate | 1 | Unknown | 2023-05-15 | 2023-05-15 |
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