St. Nikolaus-Stiftshospital GmbH
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Analytical, Diagnostic and Therapeutic Techniques and Equipment
The Gelenkzentrum Mittelrhein at St. Nikolaus-Stiftshospital is conducting innovative research on advanced cell‑based therapies for knee cartilage repair, testing the safety of BP CC 001, an umbilical cord‑derived mesenchymal stem cell suspension applied to a collagen support matrix.
- Safety assessment of umbilical cord‑derived MSC therapy for knee cartilage lesions
- Evaluation of a collagen scaffold as a delivery platform for regenerative cells
These studies aim to improve therapeutic techniques and equipment for managing cartilage defects, offering new options for patients with joint injuries.
Musculoskeletal Diseases
In the field of musculoskeletal health, the center is comparing the mid‑term outcomes of autologous minced cartilage implantation (AMCI) with matrix‑associated autologous chondrocyte implantation (M‑ACI) for large full‑thickness knee cartilage defects, using functional scores such as the KOOS to gauge effectiveness.
- Non‑inferiority trial of minced cartilage versus M‑ACI for large knee lesions
- Assessment of patient‑reported outcomes over a two‑year follow‑up
The research supports the development of less invasive surgical options and strives to enhance quality of life for individuals suffering from severe cartilage damage.
Site Overview
Activity Indicator
Last 6 months
Sponsor & Partnership
Top sponsors by active trials, and the ones that have come back for more than one study.
Sponsor Network
Top 2 by active trials.
- 1BIONCaRT GmbH1active
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Partnership History
Sponsors with repeated collaboration (≥ 2 trials).
No repeated partnerships found.
Sponsor Network Graph
How sponsors and therapeutic areas connect across this site's active trials: each link is at least one active trial shared between them, and bigger nodes mean more activity. Click a node to see its exact connections.
Country Benchmark
Compared to 2 161 other sites in Germany
Therapeutic Area Benchmark — Germany
Select a therapeutic area to compare against other sites in Germany.
Competitor Comparison
Similar sites in the same country running a comparable number of trials (within ±30%), scored on how closely their trial portfolios match this one. Higher percentages mean a more similar profile.
Country: Germany
Market Share
Country: Germany
Therapeutic Area Market Share
Select a therapeutic area to view its disease coverage breakdown.
Heat Maps & Advanced Analytics
How often specific conditions appear in trials across this site and comparable sites from the same country. Each row is a site, each column a condition, and each cell the number of trials on it — darker means more activity.
Other Trials in St. Nikolaus-Stiftshospital GmbH
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| Trial | Sponsor | Phase | Status | Start Date | End Date |
|---|---|---|---|---|---|
| Evaluation of Safety and Efficacy of Umbilical Cord-Derived Mesenchymal Stem Cells (BP CC 001) in Cartilage Defect of the Knee Joint | BIONCaRT GmbH | Phase I/II | Recruiting | Oct 2025 | — |
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