St Erik Eye Hospital

The site’s clinical research in ophthalmology focuses on conditions that affect sight and retinal function, including geographic atrophy, retinitis pigmentosa, and other eye diseases. These studies are designed to assess new treatments, monitor safety, and better understand how vision loss progresses over time.

• Testing a gene therapy approach for inherited retinal disease linked to RLBP1 mutations
• Evaluating treatment benefit in geographic atrophy related to dry age-related macular degeneration
• Following long-term safety and tolerability of therapies for degenerative retinal conditions

Research at this hospital combines safety monitoring with efforts to preserve or restore visual function, especially in patients with chronic retinal disorders.

Clinical trials in the neoplasms area at the Department of Ögon och Syn include work on rare eye tumors such as primary indeterminate lesions and small choroidal melanoma. The main goal is to evaluate how well new eye cancer treatments control disease while maintaining ocular safety.

• Assessing the effectiveness of a treatment for small choroidal melanoma and related lesions
• Comparing active therapy with sham control to understand clinical benefit
• Supporting earlier and more precise management of ocular tumors

This research supports better treatment options for patients with uncommon but serious eye cancers.

The site also studies conditions at the intersection of immune system diseases and hormonal diseases, with a focus on Graves ophthalmopathy in people newly diagnosed with Graves' disease. These trials aim to prevent eye complications and improve early disease control.

• Exploring whether treatment can reduce the risk of developing active Graves ophthalmopathy
• Investigating prevention strategies for eye involvement in thyroid-related disease
• Evaluating clinical benefit in patients at the start of Graves' disease

By focusing on early intervention, the research seeks to limit vision-threatening inflammation and support better outcomes for patients with autoimmune eye disease.

Ongoing studies at St Erik Eye Hospital include extended observation of patients with geographic atrophy secondary to age-related macular degeneration and related retinal conditions. These trials are intended to track durability of benefit, continued safety, and changes in vision over time.

• Monitoring long-term safety after treatment for geographic atrophy
• Observing whether vision-related effects remain stable over time
• Collecting follow-up data to inform future retinal disease care

The research reflects a strong interest in chronic retinal disorders, with attention to both patient safety and lasting treatment impact.