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Pula General Hospital Ospedale Generale di Pola

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Cardiovascular Diseases

At Pula General Hospital Ospedale Generale di Pola, investigators are evaluating a novel lipid‑lowering therapy to reduce the incidence of major adverse cardiovascular events in high‑risk patients as part of primary prevention efforts.

  • Evaluation of inclisiran for ASCVD primary prevention
  • Cardiovascular safety monitoring in immunotherapy combination trials
  • Long‑term outcome assessment in patients with elevated cardiovascular risk

The department contributes several of the nine ongoing trials, with a team of seven investigators guiding the research.

Neoplasms

The oncology division is testing cutting‑edge immunotherapies and biosimilars to improve outcomes for individuals with metastatic non‑small cell lung cancer, focusing on response rates and safety profiles.

  • Comparison of new checkpoint inhibitor combinations in NSCLC
  • Biosimilar equivalence study with Keytruda (CT‑P51)
  • Second‑line acasunlimab plus pembrolizumab versus standard docetaxel
  • Fixed‑dose combination safety of tiragolumab and atezolizumab

Across the nine trials, lung cancer remains a central focus, leveraging the expertise of seven clinical investigators.

Nervous System Diseases

A dedicated study is examining a new agent for agitation in Alzheimer’s‑type dementia, aiming to provide a safer option that eases behavioral disturbances while maintaining tolerability.

  • Safety and tolerability assessment of AVP‑786
  • Behavioral outcome measures in dementia patients
  • Quality‑of‑life impact evaluation for caregivers

This trial reflects the department’s commitment to improving neurological care alongside its oncology and cardiovascular programs.

Nutritional and Metabolic Diseases

Researchers are investigating an investigational compound that promotes weight loss and enhances glycemic control in adults with obesity and type 2 diabetes, with the goal of lowering cardiovascular risk.

  • Effect of NNC0487‑0111 on body weight reduction
  • Impact on glucose metabolism and HbA1c levels
  • Safety and tolerability profile in overweight participants

These metabolic studies complement the cardiovascular prevention initiatives underway at the hospital.

Site Overview

assignment
9
connected trials
corporate_fare
8
sponsors
science
18
IMPs

Activity Indicator

Last 6 months

1
Trials started
New activity detected vs previous period.
0
Trials started 6–12 months ago
9
Total trials linked
Active
trending_upGrowing+100%
1
Mar
Apr
May
Jun
Jul
Aug

Trial Flow

How this site's trials are distributed across therapeutic areas and active substances (IMPs), and how they're positioned within their overall lifecycle status. Flow thickness represents the number of unique trials.

Therapeutic areaarrow_forwardIMParrow_forwardLifecycle status

Top 3 therapeutic areas and 15 of 18 IMPs, ranked by number of trials.

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Compounds & Molecules Timeline

The time span of clinical-trial activity for the main active substances (IMPs) studied at this site over the last 8 years. Each bar runs from the earliest trial start to the most recent end; a substance with a trial still open has no recorded end and is shown as ongoing.

Trial span Ongoing Showing last 8 years
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Sponsor & Partnership

Top sponsors by active trials, and the ones that have come back for more than one study.

Active trials
2
Sponsors (total)
8
Active sponsors
2

Sponsor Network

Top 2 by active trials.

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Partnership History

Sponsors with repeated collaboration (≥ 2 trials).

Sponsor Network Graph

How sponsors and therapeutic areas connect across this site's active trials: each link is at least one active trial shared between them, and bigger nodes mean more activity. Click a node to see its exact connections.

Country Benchmark

Compared to 60 other sites in Croatia

description
Trial volume
9
Outperforms 65% of sites
public
Therapeutic diversity
4areas
Outperforms 67% of sites
groups
Sponsor diversity
8sponsors
Outperforms 70% of sites

Therapeutic Area Benchmark — Croatia

Select a therapeutic area to compare against other sites in Croatia.

Competitor Comparison

Similar sites in the same country running a comparable number of trials (within ±30%), scored on how closely their trial portfolios match this one. Higher percentages mean a more similar profile.

Country: Croatia

Market Share

Country: Croatia

Therapeutic Area Market Share

Select a therapeutic area to view its disease coverage breakdown.

Heat Maps & Advanced Analytics

How often specific conditions appear in trials across this site and comparable sites from the same country. Each row is a site, each column a condition, and each cell the number of trials on it — darker means more activity.

Other Trials in Pula General Hospital Ospedale Generale di Pola

lock Showing 1 of 9 trials — the rest is available on a paid plan.

Trial Sponsor Phase Status Start Date End Date
Comparative Study of Pharmacokinetics, Efficacy, Safety, and Immunogenicity of MB12 and Pembrolizumab in Advanced/Metastatic Non-Squamous NSCLCMabxience Research S.L.Phase IIIRecruitingSep 2025

IMP list

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IMP Trials Status First start Last start
Pembrolizumab3Unknown2024-10-012025-02-21

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