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Provincia Lombardo Veneta Dell’ordine Ospedaliero Di San Giovanni Di Dio Fatebenefratelli

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Nervous System Diseases and Alzheimer’s Research

At Provincia Lombardo Veneta Dell’ordine Ospedaliero Di San Giovanni Di Dio Fatebenefratelli in Brescia, most studies focus on Alzheimer’s disease and related neurodegenerative diseases. The research is aimed at finding new ways to slow cognitive decline, protect brain function, and improve overall disease management.

  • Testing new therapies for mild to moderate Alzheimer’s disease dementia
  • Evaluating treatments intended to preserve memory and thinking skills
  • Studying long-term safety and tolerability of investigational approaches
  • Exploring biomarkers linked to disease progression and treatment response

This work reflects a strong clinical interest in both treatment effectiveness and early intervention for people living with or at risk for Alzheimer’s disease.

Psychiatry and Psychology in Alzheimer’s-Related Mental Disorders

The site also investigates mental disorders linked to dementia, especially psychosis associated with Alzheimer’s disease and agitation. These trials are designed to improve behavioral symptoms that can greatly affect quality of life for patients and caregivers.

  • Assessing treatments for psychosis in Alzheimer’s disease
  • Studying options to reduce hallucinations and delusions
  • Evaluating therapies for agitation in Alzheimer’s disease dementia
  • Measuring how well symptom control can be maintained over time

This area combines psychiatric care with dementia research to address some of the most challenging symptoms seen in advanced Alzheimer’s disease.

Genetic Alzheimer’s Disease and Prevention Research

Another important line of research at this hospital/clinic involves Dominantly Inherited Alzheimer Disease and other inherited forms of early-onset dementia. The studies aim to learn whether treatment can delay or prevent disease onset in people carrying disease-causing mutations.

  • Studying prevention strategies for people at genetic risk for Alzheimer’s disease
  • Tracking changes in brain-related biomarkers linked to early disease activity
  • Evaluating whether investigational treatments can slow progression before symptoms worsen
  • Supporting research in families affected by inherited neurodegenerative disease

This research is especially valuable for understanding how Alzheimer’s disease develops and how it might be delayed before major cognitive decline begins.

Depression and Inflammation-Related Mental Health Research

The site includes work in psychiatry beyond dementia, with a study focused on depression and the role of inflammation in treatment response. The goal is to better understand whether adding a new therapy can improve symptoms and biological markers in patients already receiving standard care.

  • Investigating treatment effects in depressed patients
  • Exploring links between mood symptoms and peripheral inflammatory status
  • Assessing whether symptoms improve alongside biological changes
  • Supporting broader research into personalized approaches for mental disorders

This adds an important non-dementia dimension to the research portfolio, connecting psychiatry with biological markers of disease.

Site Overview

assignment
12
connected trials
corporate_fare
9
sponsors
science
14
IMPs

Activity Indicator

Last 6 months

1
Trials started
New activity detected vs previous period.
0
Trials started 6–12 months ago
12
Total trials linked
Highly Active
trending_upGrowing+100%
1
Mar
Apr
May
Jun
Jul
Aug

Trial Flow

How this site's trials are distributed across therapeutic areas and active substances (IMPs), and how they're positioned within their overall lifecycle status. Flow thickness represents the number of unique trials.

Therapeutic areaarrow_forwardIMParrow_forwardLifecycle status
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Compounds & Molecules Timeline

The time span of clinical-trial activity for the main active substances (IMPs) studied at this site over the last 8 years. Each bar runs from the earliest trial start to the most recent end; a substance with a trial still open has no recorded end and is shown as ongoing.

Trial span Ongoing Showing last 8 years
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Sponsor & Partnership

Top sponsors by active trials, and the ones that have come back for more than one study.

Active trials
6
Sponsors (total)
9
Active sponsors
6

Sponsor Network

Top 6 by active trials.

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Partnership History

Sponsors with repeated collaboration (≥ 2 trials).

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Sponsor Network Graph

How sponsors and therapeutic areas connect across this site's active trials: each link is at least one active trial shared between them, and bigger nodes mean more activity. Click a node to see its exact connections.

Country Benchmark

Compared to 566 other sites in Italy

description
Trial volume
12
Outperforms 70% of sites
public
Therapeutic diversity
2areas
Outperforms 41% of sites
groups
Sponsor diversity
9sponsors
Outperforms 69% of sites

Therapeutic Area Benchmark — Italy

Select a therapeutic area to compare against other sites in Italy.

Competitor Comparison

Similar sites in the same country running a comparable number of trials (within ±30%), scored on how closely their trial portfolios match this one. Higher percentages mean a more similar profile.

Country: Italy

Market Share

Country: Italy

Therapeutic Area Market Share

Select a therapeutic area to view its disease coverage breakdown.

Heat Maps & Advanced Analytics

How often specific conditions appear in trials across this site and comparable sites from the same country. Each row is a site, each column a condition, and each cell the number of trials on it — darker means more activity.

Other Trials in Provincia Lombardo Veneta Dell’ordine Ospedaliero Di San Giovanni Di Dio Fatebenefratelli

lock Showing 1 of 12 trials — the rest is available on a paid plan.

Trial Sponsor Phase Status Start Date End Date
Continuation Study of Latozinemab in Patients with Neurodegenerative Diseases Following Prior Participation in Alector-Sponsored TrialsAlector LLCPhase IIINot RecruitingSep 2024Jan 2026

IMP list

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IMP Trials Status First start Last start
Trospium Chloride3Unknown2024-05-092025-08-25

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