local_hospital

Poliklinika Borzan d.o.o.

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Digestive System Diseases

The site concentrates on inflammatory bowel disease research, investigating both Crohn’s disease and ulcerative colitis, as well as celiac disease in patients with persistent symptoms.

  • Evaluation of novel biologic agents for induction and maintenance therapy
  • Oral small‑molecule treatments targeting gut inflammation
  • Biosimilar comparison studies to improve access
  • Combination regimens that integrate immunomodulators
  • Long‑term safety and tolerability assessments

Poliklinika Borzan d.o.o. is currently running 29 trials led by three investigators, aiming to bring effective options to patients with moderate to severe gastrointestinal disorders.

Immune System Diseases

Clinical work at the clinic addresses immune‑mediated gastrointestinal disorders, focusing on therapies that modulate key cytokine pathways.

  • Targeted therapies such as IL‑23 and IL‑12/23 inhibitors
  • Cytokine blockade using monoclonal antibodies
  • Mechanistic profiling to understand drug action
  • Comparative studies of existing biologics versus new agents
  • Evaluation of safety in patients naïve to biologic treatment

Ongoing studies include head‑to‑head trials of risankizumab versus vedolizumab, and investigations of combination strategies with upadacitinib.

Immune System Phenomena

Research also explores the underlying immune system phenomena that drive disease activity, aiming to personalize therapy.

  • Therapeutic drug monitoring to guide dose adjustments
  • Biomarker discovery for predicting response
  • Immune phenotyping of patient sub‑groups
  • Safety profiling of long‑term immunosuppression
  • Evaluation of endoscopic and histologic endpoints

These efforts support the development of precision approaches, ensuring that patients receive the most appropriate treatment based on their individual immune profile.

Site Overview

assignment
30
connected trials
corporate_fare
17
sponsors
science
20
IMPs

Activity Indicator

Last 6 months

3
Trials started
-25% vs previous period.
4
Trials started 6–12 months ago
30
Total trials linked
Highly Active
trending_downDeclining-25%
1
2
Mar
Apr
May
Jun
Jul
Aug

Trial Flow

How this site's trials are distributed across therapeutic areas and active substances (IMPs), and how they're positioned within their overall lifecycle status. Flow thickness represents the number of unique trials.

Therapeutic areaarrow_forwardIMParrow_forwardLifecycle status

Top 2 of 3 therapeutic areas and 15 of 20 IMPs, ranked by number of trials.

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Compounds & Molecules Timeline

The time span of clinical-trial activity for the main active substances (IMPs) studied at this site over the last 8 years. Each bar runs from the earliest trial start to the most recent end; a substance with a trial still open has no recorded end and is shown as ongoing.

Trial span Ongoing Showing last 8 years
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Sponsor & Partnership

Top sponsors by active trials, and the ones that have come back for more than one study.

Active trials
15
Sponsors (total)
17
Active sponsors
11

Sponsor Network

Top 11 by active trials.

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Partnership History

Sponsors with repeated collaboration (≥ 2 trials).

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Sponsor Network Graph

How sponsors and therapeutic areas connect across this site's active trials: each link is at least one active trial shared between them, and bigger nodes mean more activity. Click a node to see its exact connections.

Country Benchmark

Compared to 60 other sites in Croatia

description
Trial volume
30
Outperforms 85% of sites
public
Therapeutic diversity
3areas
Outperforms 58% of sites
groups
Sponsor diversity
17sponsors
Outperforms 85% of sites

Therapeutic Area Benchmark — Croatia

Select a therapeutic area to compare against other sites in Croatia.

Competitor Comparison

Similar sites in the same country running a comparable number of trials (within ±30%), scored on how closely their trial portfolios match this one. Higher percentages mean a more similar profile.

Country: Croatia

Market Share

Country: Croatia

Therapeutic Area Market Share

Select a therapeutic area to view its disease coverage breakdown.

Heat Maps & Advanced Analytics

How often specific conditions appear in trials across this site and comparable sites from the same country. Each row is a site, each column a condition, and each cell the number of trials on it — darker means more activity.

Other Trials in Poliklinika Borzan d.o.o.

lock Showing 1 of 30 trials — the rest is available on a paid plan.

Trial Sponsor Phase Status Start Date End Date
A Phase 1, Randomized, Double-Blind, Placebo-Controlled Study in Healthy Participants Followed by a Randomized, Double-Blind, Placebo-Controlled Phase 2 Study in Participants with Moderate-to-Severe Active Ulcerative Colitis.Xencor Inc.Phase IIRecruitingJan 2026

IMP list

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IMP Trials Status First start Last start
Risankizumab4Unknown2017-11-082025-07-23

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