local_hospital

Ospedale Santa Maria Annunziata

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Immune System Diseases

The research team at Ospedale Santa Maria Annunziata investigates disorders of the immune system, notably IgA nephropathy and chronic kidney injury, seeking therapies that lower protein loss and preserve renal function.

  • Early corticosteroid treatment after kidney biopsy
  • SGLT2 inhibitor combined with renin‑angiotensin blockade
  • Non‑inferiority of glucose‑sparing dialysis solutions

These studies aim to improve patient outcomes while reducing treatment‑related side effects, positioning the site as a hub for innovative renal research in Europe.

Male Urogenital Diseases

Although current trials focus on other specialties, the department is equipped to conduct studies on male urogenital conditions, leveraging its multidisciplinary expertise and modern facilities.

  • Evaluation of novel hormonal therapies
  • Assessment of minimally invasive surgical techniques
  • Quality‑of‑life measurements in urologic patients

The hospital’s commitment to expanding research in this therapeutic area promises future opportunities for patients and investigators alike.

Neoplasms

The oncology program concentrates on a range of cancers, including breast cancer, melanoma, and metastatic colorectal cancer, with trials designed to test targeted agents and combination regimens.

  • PIK3CA‑mutated hormone‑positive breast cancer therapy
  • First‑line FOLFIRI with cetuximab or bevacizumab in RAS/BRAF‑selected mCRC
  • Neoadjuvant plus adjuvant vemurafenib, cobimetinib, and atezolizumab for high‑risk melanoma

These investigations seek to enhance survival and disease‑free intervals, offering patients access to cutting‑edge treatments within a leading European cancer center.

Virus Diseases

In the field of viral infections, the site conducts research on HIV‑1 management, focusing on regimen simplification and long‑term viral suppression.

  • Early switch to a two‑drug dolutegravir/lamivudine regimen
  • Virologic rebound monitoring using FDA snapshot criteria
  • Patient‑reported outcomes on treatment tolerability

The goal is to maintain effective control of the virus while reducing pill burden and potential side effects, contributing valuable data to global HIV care strategies.

Site Overview

assignment
10
connected trials
corporate_fare
9
sponsors
science
36
IMPs

Activity Indicator

Last 6 months

0
Trials started
0
Trials started 6–12 months ago
10
Total trials linked
Highly Active
trending_flatStable0%
Mar
Apr
May
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Trial Flow

How this site's trials are distributed across therapeutic areas and active substances (IMPs), and how they're positioned within their overall lifecycle status. Flow thickness represents the number of unique trials.

Therapeutic areaarrow_forwardIMParrow_forwardLifecycle status

Top 5 therapeutic areas and 15 of 36 IMPs, ranked by number of trials.

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Compounds & Molecules Timeline

The time span of clinical-trial activity for the main active substances (IMPs) studied at this site over the last 8 years. Each bar runs from the earliest trial start to the most recent end; a substance with a trial still open has no recorded end and is shown as ongoing.

Trial span Ongoing Showing last 8 years
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Sponsor & Partnership

Top sponsors by active trials, and the ones that have come back for more than one study.

Active trials
6
Sponsors (total)
9
Active sponsors
6

Sponsor Network

Top 6 by active trials.

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Partnership History

Sponsors with repeated collaboration (≥ 2 trials).

Sponsor Network Graph

How sponsors and therapeutic areas connect across this site's active trials: each link is at least one active trial shared between them, and bigger nodes mean more activity. Click a node to see its exact connections.

Country Benchmark

Compared to 566 other sites in Italy

description
Trial volume
10
Outperforms 68% of sites
public
Therapeutic diversity
5areas
Outperforms 71% of sites
groups
Sponsor diversity
9sponsors
Outperforms 69% of sites

Therapeutic Area Benchmark — Italy

Select a therapeutic area to compare against other sites in Italy.

Competitor Comparison

Similar sites in the same country running a comparable number of trials (within ±30%), scored on how closely their trial portfolios match this one. Higher percentages mean a more similar profile.

Country: Italy

Market Share

Country: Italy

Therapeutic Area Market Share

Select a therapeutic area to view its disease coverage breakdown.

Heat Maps & Advanced Analytics

How often specific conditions appear in trials across this site and comparable sites from the same country. Each row is a site, each column a condition, and each cell the number of trials on it — darker means more activity.

Other Trials in Ospedale Santa Maria Annunziata

lock Showing 1 of 10 trials — the rest is available on a paid plan.

Trial Sponsor Phase Status Start Date End Date
A Phase 3 Randomized Trial of Endocrine Therapy Versus Radiation Therapy in Women Aged ≥70 with Luminal A-like Early Stage Breast CancerUniversity Of FlorencePhase IIIRecruitingFeb 2021

IMP list

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IMP Trials Status First start Last start
Sodium Chloride2Unknown2023-07-062023-08-30

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