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Oslo University Hospital Hf

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Lipid‑lowering therapies

The Lipid Clinic at Oslo University Hospital Hf conducts research focused on cardiovascular diseases and nutritional and metabolic disorders, especially conditions driven by high triglycerides and cholesterol. Trials aim to test new agents that lower lipid levels, improve safety profiles, and potentially reduce heart‑related events.

  • Olezarsen for severe hypertriglyceridemia and atherosclerotic disease
  • Olpasiran targeting lipoprotein(a) to lower cardiovascular risk
  • MK‑0616 oral therapy evaluating LDL‑C reduction

These studies bring together six investigators and seek to expand treatment options for patients with elevated triglycerides, high LDL‑C, and increased Lp(a) levels.

Acute hemorrhage management

In the realm of stroke and intracerebral bleeding, the site evaluates rapid‑acting drugs that may lower early mortality. The primary goal is to determine whether early administration improves survival within the first week after a bleed.

  • Tranexamic acid safety and effect on early death after spontaneous ICH

By enrolling patients with hyperacute hemorrhage, the research team hopes to inform clinical practice on the use of antifibrinolytic therapy.

Genetic and atherosclerotic lipid disorders

Studies at the clinic also address inherited and plaque‑related conditions such as heterozygous familial hypercholesterolemia and extensive atherosclerosis. The objective is to assess how novel lipid‑targeting drugs influence disease progression and cardiovascular outcomes.

  • Evaluating LDL‑C lowering efficacy in HeFH patients
  • Measuring impact of Lp(a) reduction on coronary events in ASCVD

These investigations complement the broader effort to improve heart health for individuals with high‑risk lipid profiles.

Site Overview

assignment
5
connected trials
corporate_fare
4
sponsors
science
4
IMPs

Activity Indicator

Last 6 months

0
Trials started
0
Trials started 6–12 months ago
5
Total trials linked
Active
trending_flatStable0%
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Trial Flow

How this site's trials are distributed across therapeutic areas and active substances (IMPs), and how they're positioned within their overall lifecycle status. Flow thickness represents the number of unique trials.

Therapeutic areaarrow_forwardIMParrow_forwardLifecycle status
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Compounds & Molecules Timeline

The time span of clinical-trial activity for the main active substances (IMPs) studied at this site over the last 8 years. Each bar runs from the earliest trial start to the most recent end; a substance with a trial still open has no recorded end and is shown as ongoing.

Trial span Ongoing Showing last 8 years
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Sponsor & Partnership

Top sponsors by active trials, and the ones that have come back for more than one study.

Active trials
1
Sponsors (total)
4
Active sponsors
1

Sponsor Network

Top 1 by active trials.

Partnership History

Sponsors with repeated collaboration (≥ 2 trials).

Sponsor Network Graph

How sponsors and therapeutic areas connect across this site's active trials: each link is at least one active trial shared between them, and bigger nodes mean more activity. Click a node to see its exact connections.

Country Benchmark

Compared to 112 other sites in Norway

description
Trial volume
5
Outperforms 72% of sites
public
Therapeutic diversity
2areas
Outperforms 63% of sites
groups
Sponsor diversity
4sponsors
Outperforms 68% of sites

Therapeutic Area Benchmark — Norway

Select a therapeutic area to compare against other sites in Norway.

Competitor Comparison

Similar sites in the same country running a comparable number of trials (within ±30%), scored on how closely their trial portfolios match this one. Higher percentages mean a more similar profile.

Country: Norway

Market Share

Country: Norway

Therapeutic Area Market Share

Select a therapeutic area to view its disease coverage breakdown.

Heat Maps & Advanced Analytics

How often specific conditions appear in trials across this site and comparable sites from the same country. Each row is a site, each column a condition, and each cell the number of trials on it — darker means more activity.

Other Trials in Oslo University Hospital Hf

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Trial Sponsor Phase Status Start Date End Date
A Phase 3, Randomized, Double-Blind, Placebo-Controlled Study to Evaluate the Efficacy and Safety of MK-0616 in Adults With Heterozygous Familial HypercholesterolemiaMerck Sharp & Dohme LLCPhase IIINot RecruitingSep 2023Apr 2025

IMP list

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IMP Trials Status First start Last start
Isis 678354 Sodium Salt2Unknown2023-06-082023-07-12

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