local_hospital

Nemocnice AGEL Ostrava-Vitkovice a.s.

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Neoplasms

The department focuses on malignant lung tumors, primarily Non‑Small Cell Lung Cancer. It also studies Small Cell Lung Cancer. Ongoing trials evaluate novel targeted therapies such as EGFR, KRAS and HER2 inhibitors, and combine them with immunotherapy to improve disease‑free and overall survival.

  • Combination of EGFR or KRAS inhibitors with chemotherapy
  • Adjuvant pembrolizumab after surgical resection
  • Selpercatinib for RET‑fusion positive disease
  • Dual checkpoint blockade in limited‑stage small‑cell lung cancer
  • Dose‑optimization studies of novel agents in KRAS‑mutant tumors

Nemocnice AGEL Ostrava‑Vitkovice a.s. is running 20 clinical trials with six investigators, reflecting a robust thoracic oncology program.

Respiratory Tract Diseases

Research at the site covers a wide range of lung conditions, with a strong emphasis on advanced carcinoma. Trials aim to assess new systemic regimens and post‑surgical strategies that can lower recurrence rates and extend patient survival.

  • Adjuvant V940 plus pembrolizumab in resected stage II‑IIIA disease
  • MK‑2870 combined with pembrolizumab versus pembrolizumab alone
  • Tarlatamab plus durvalumab versus durvalumab monotherapy in extensive‑stage SCLC
  • Olomorasib (LY3537982) with standard of care for KRAS‑G12C mutant NSCLC
  • Comparison of ensartinib versus crizotinib in ALK‑positive NSCLC

The multidisciplinary team integrates pulmonology and oncology expertise, supporting patient enrollment across the Czech Republic.

Site Overview

assignment
28
connected trials
corporate_fare
15
sponsors
science
60
IMPs

Activity Indicator

Last 6 months

3
Trials started
+50% vs previous period.
2
Trials started 6–12 months ago
28
Total trials linked
Highly Active
trending_upGrowing+50%
1
1
1
Mar
Apr
May
Jun
Jul
Aug

Trial Flow

How this site's trials are distributed across therapeutic areas and active substances (IMPs), and how they're positioned within their overall lifecycle status. Flow thickness represents the number of unique trials.

Therapeutic areaarrow_forwardIMParrow_forwardLifecycle status

Top 3 of 4 therapeutic areas and 15 of 60 IMPs, ranked by number of trials.

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Compounds & Molecules Timeline

The time span of clinical-trial activity for the main active substances (IMPs) studied at this site over the last 8 years. Each bar runs from the earliest trial start to the most recent end; a substance with a trial still open has no recorded end and is shown as ongoing.

Trial span Ongoing Showing last 8 years

Top 40 of 60 compounds, ranked by number of trials.

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Sponsor & Partnership

Top sponsors by active trials, and the ones that have come back for more than one study.

Active trials
14
Sponsors (total)
15
Active sponsors
8

Sponsor Network

Top 8 by active trials.

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Partnership History

Sponsors with repeated collaboration (≥ 2 trials).

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Sponsor Network Graph

How sponsors and therapeutic areas connect across this site's active trials: each link is at least one active trial shared between them, and bigger nodes mean more activity. Click a node to see its exact connections.

Country Benchmark

Compared to 634 other sites in Czechia

description
Trial volume
28
Outperforms 93% of sites
public
Therapeutic diversity
4areas
Outperforms 88% of sites
groups
Sponsor diversity
15sponsors
Outperforms 93% of sites

Therapeutic Area Benchmark — Czechia

Select a therapeutic area to compare against other sites in Czechia.

Competitor Comparison

Similar sites in the same country running a comparable number of trials (within ±30%), scored on how closely their trial portfolios match this one. Higher percentages mean a more similar profile.

Country: Czechia

Market Share

Country: Czechia

Therapeutic Area Market Share

Select a therapeutic area to view its disease coverage breakdown.

Heat Maps & Advanced Analytics

How often specific conditions appear in trials across this site and comparable sites from the same country. Each row is a site, each column a condition, and each cell the number of trials on it — darker means more activity.

Other Trials in Nemocnice AGEL Ostrava-Vitkovice a.s.

lock Showing 1 of 28 trials — the rest is available on a paid plan.

Trial Sponsor Phase Status Start Date End Date
A phase 2b, multinational, randomized, double-blind study to investigate the efficacy and safety of redasemtide (S-005151) compared with placebo in adult participants with acute ischemic strokeShionogi B.V.Phase IINot Yet RecruitingFeb 2024Jun 2026

IMP list

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IMP Trials Status First start Last start
Carboplatin11Unknown2020-09-292026-06-01

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