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Narodny Ustav Detskych Chorob

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Bacterial Infections and Mycoses

The site investigates treatments for serious bacterial and fungal infections in children, aiming to improve safety and effectiveness.

  • Complicated urinary tract infections
  • Acute bacterial sepsis
  • Hospital‑acquired fungal infections

Research includes evaluating new antimicrobial agents and optimizing dosing strategies to reduce infection‑related complications.

Congenital, Hereditary, and Neonatal Diseases and Abnormalities

Studies focus on rare inherited disorders that affect infants and children, seeking better therapeutic options.

  • Osteogenesis Imperfecta
  • Primary Immunodeficiency Diseases
  • Genetic metabolic syndromes

Trials assess gene‑targeted therapies and immune‑supportive products to enhance growth and immune function.

Eye Diseases

Pediatric eye health is addressed through trials that aim to slow disease progression and improve visual outcomes.

  • Myopia progression
  • Pediatric uveitis
  • Congenital cataract

The research evaluates novel ophthalmic solutions and device‑based interventions to preserve vision.

Hemic and Lymphatic Diseases

The clinic conducts extensive research on blood‑related cancers, testing innovative therapies to increase survival rates.

  • Acute Lymphoblastic Leukaemia
  • Lymphoblastic lymphoma
  • Anaplastic Large Cell Lymphoma
  • Neuroblastoma
  • Rhabdomyosarcoma
  • Ewing sarcoma

Efforts include immunotherapy, targeted agents, and stem‑cell transplantation to improve long‑term remission.

Immune System Diseases

Trials target disorders of immune regulation, aiming to restore balance and reduce disease activity.

  • Multiple Sclerosis
  • Atopic Dermatitis
  • Primary Immunodeficiency Diseases

Studies compare novel biologics with existing standards to determine superior efficacy and safety.

Musculoskeletal Diseases

Research seeks to strengthen bone health and reduce fracture risk in children with skeletal fragility.

  • Osteogenesis Imperfecta
  • Juvenile idiopathic arthritis
  • Muscular dystrophy

Investigations include bone‑forming agents and rehabilitation protocols to enhance mobility.

Neoplasms

A broad portfolio of cancer trials evaluates cutting‑edge treatments across solid and hematologic tumors in young patients.

  • Hepatoblastoma
  • High‑risk neuroblastoma
  • Relapsed acute lymphoblastic leukemia
  • Metastatic sarcomas

The program emphasizes personalized medicine, combining targeted drugs with conventional chemotherapy.

Nervous System Diseases

Neurological conditions are studied to improve function and quality of life for affected children.

  • Multiple Sclerosis
  • Chronic Migraine
  • Neurogenic Detrusor Overactivity

Trials test neuromodulators and disease‑modifying therapies to reduce symptom burden.

Nutritional and Metabolic Diseases

Metabolic health research addresses obesity and related disorders to promote healthier growth trajectories.

  • Obesity
  • Type 2 Diabetes
  • Metabolic syndrome

Interventions include lifestyle programs and novel metabolic agents aimed at weight management.

Pathological Conditions, Signs and Symptoms

Studies focus on common pediatric symptoms to develop better diagnostic tools and symptom‑relief strategies.

  • Atopic Dermatitis
  • Chronic Migraine
  • Painful urination

The work integrates patient‑reported outcomes to tailor therapies to individual needs.

Skin and Connective Tissue Diseases

Dermatologic trials aim to control inflammation and prevent long‑term skin damage in children.

  • Atopic Dermatitis
  • Pediatric psoriasis
  • Connective tissue disorders

Innovative topical agents and systemic treatments are evaluated for safety and rapid symptom control.

Virus Diseases

Viral infection research, especially COVID‑19, seeks effective treatments for immunocompromised children.

  • COVID‑19
  • Pediatric influenza
  • Viral gastroenteritis

Studies assess antiviral combinations and immune‑boosting strategies to reduce severe outcomes.

Immune System Processes

Fundamental investigations explore how the immune system functions in health and disease, guiding future therapeutic design.

  • Immune cell signaling
  • Complement pathway regulation
  • Cytokine storm mitigation

Findings support the development of next‑generation immunomodulators for pediatric use.

Site Overview

assignment
32
connected trials
corporate_fare
23
sponsors
science
93
IMPs

Activity Indicator

Last 6 months

2
Trials started
0% vs previous period.
2
Trials started 6–12 months ago
32
Total trials linked
Highly Active
trending_flatStable0%
1
1
Mar
Apr
May
Jun
Jul
Aug

Trial Flow

How this site's trials are distributed across therapeutic areas and active substances (IMPs), and how they're positioned within their overall lifecycle status. Flow thickness represents the number of unique trials.

Therapeutic areaarrow_forwardIMParrow_forwardLifecycle status

Top 2 of 14 therapeutic areas and 15 of 93 IMPs, ranked by number of trials.

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Compounds & Molecules Timeline

The time span of clinical-trial activity for the main active substances (IMPs) studied at this site over the last 8 years. Each bar runs from the earliest trial start to the most recent end; a substance with a trial still open has no recorded end and is shown as ongoing.

Trial span Ongoing Showing last 8 years

Top 40 of 85 compounds, ranked by number of trials.

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Sponsor & Partnership

Top sponsors by active trials, and the ones that have come back for more than one study.

Active trials
19
Sponsors (total)
23
Active sponsors
18

Sponsor Network

Top 18 by active trials.

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Partnership History

Sponsors with repeated collaboration (≥ 2 trials).

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Sponsor Network Graph

How sponsors and therapeutic areas connect across this site's active trials: each link is at least one active trial shared between them, and bigger nodes mean more activity. Click a node to see its exact connections.

Country Benchmark

Compared to 353 other sites in Slovakia

description
Trial volume
32
Outperforms 97% of sites
public
Therapeutic diversity
14areas
Outperforms 99% of sites
groups
Sponsor diversity
23sponsors
Outperforms 99% of sites

Therapeutic Area Benchmark — Slovakia

Select a therapeutic area to compare against other sites in Slovakia.

Competitor Comparison

Similar sites in the same country running a comparable number of trials (within ±30%), scored on how closely their trial portfolios match this one. Higher percentages mean a more similar profile.

Country: Slovakia

Market Share

Country: Slovakia

Therapeutic Area Market Share

Select a therapeutic area to view its disease coverage breakdown.

Heat Maps & Advanced Analytics

How often specific conditions appear in trials across this site and comparable sites from the same country. Each row is a site, each column a condition, and each cell the number of trials on it — darker means more activity.

Other Trials in Narodny Ustav Detskych Chorob

lock Showing 1 of 32 trials — the rest is available on a paid plan.

Trial Sponsor Phase Status Start Date End Date
A Phase 3, Open-label, Uncontrolled Study to Evaluate the Activity, Safety, Pharmacokinetics and Pharmacodynamics of Roxadustat for the Treatment of Anemia in Pediatric Participants with Chronic Kidney DiseaseAstellas Pharma Global Development Inc.Phase IIIRecruitingDec 2023

IMP list

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IMP Trials Status First start Last start
Etoposide5Unknown2014-03-272024-11-21

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