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Narodny Onkologicky Ustav

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Oncology – Solid Tumors

Narodny Onkologicky Ustav is conducting trials that explore new treatment options for prostate cancer, breast cancer, and other solid malignancies, aiming to improve survival and quality of life.

  • Pre‑operative chemotherapy for high‑risk retroperitoneal sarcoma
  • Combination of XL092 with immunotherapy for non‑clear cell renal cell carcinoma
  • Androgen deprivation therapy plus darolutamide for metastatic prostate cancer
  • Novel oral degrader ARV‑471 versus standard endocrine therapy in advanced breast cancer

The research emphasizes personalized approaches and integrates surgical and systemic strategies to advance care for patients across Bratislava and beyond.

Oncology – Hematologic Malignancies

Clinical studies at the site focus on innovative therapies for blood cancers such as follicular lymphoma and diffuse large B‑cell lymphoma, seeking to extend remission periods and reduce disease burden.

  • CAR‑T cell therapy tisagenlecleucel compared with standard care for relapsed follicular lymphoma
  • Epcoritamab combined with R‑CHOP versus R‑CHOP alone for newly diagnosed diffuse large B‑cell lymphoma

These trials highlight the institution’s commitment to bringing cutting‑edge immunotherapies to patients in Central Europe.

Cardiovascular – Anticoagulation Management

A dedicated trial evaluates rapid reversal agents for patients on factor Xa inhibitors, aiming to safely manage bleeding risk during urgent procedures.

  • Andexanet alfa versus usual care for intra‑operative hemostasis in patients requiring urgent surgery

By addressing critical bleeding scenarios, the study supports safer surgical outcomes for individuals on modern anticoagulant therapy.

Site Overview

assignment
40
connected trials
corporate_fare
18
sponsors
science
126
IMPs

Activity Indicator

Last 6 months

0
Trials started
-100% vs previous period.
5
Trials started 6–12 months ago
40
Total trials linked
Highly Active
trending_downDeclining-100%
Mar
Apr
May
Jun
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Trial Flow

How this site's trials are distributed across therapeutic areas and active substances (IMPs), and how they're positioned within their overall lifecycle status. Flow thickness represents the number of unique trials.

Therapeutic areaarrow_forwardIMParrow_forwardLifecycle status

Top 3 of 6 therapeutic areas and 15 of 126 IMPs, ranked by number of trials.

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Compounds & Molecules Timeline

The time span of clinical-trial activity for the main active substances (IMPs) studied at this site over the last 8 years. Each bar runs from the earliest trial start to the most recent end; a substance with a trial still open has no recorded end and is shown as ongoing.

Trial span Ongoing Showing last 8 years

Top 40 of 111 compounds, ranked by number of trials.

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Sponsor & Partnership

Top sponsors by active trials, and the ones that have come back for more than one study.

Active trials
19
Sponsors (total)
18
Active sponsors
13

Sponsor Network

Top 13 by active trials.

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Partnership History

Sponsors with repeated collaboration (≥ 2 trials).

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Sponsor Network Graph

How sponsors and therapeutic areas connect across this site's active trials: each link is at least one active trial shared between them, and bigger nodes mean more activity. Click a node to see its exact connections.

Country Benchmark

Compared to 353 other sites in Slovakia

description
Trial volume
40
Outperforms 98% of sites
public
Therapeutic diversity
6areas
Outperforms 94% of sites
groups
Sponsor diversity
18sponsors
Outperforms 97% of sites

Therapeutic Area Benchmark — Slovakia

Select a therapeutic area to compare against other sites in Slovakia.

Competitor Comparison

Similar sites in the same country running a comparable number of trials (within ±30%), scored on how closely their trial portfolios match this one. Higher percentages mean a more similar profile.

Country: Slovakia

Market Share

Country: Slovakia

Therapeutic Area Market Share

Select a therapeutic area to view its disease coverage breakdown.

Heat Maps & Advanced Analytics

How often specific conditions appear in trials across this site and comparable sites from the same country. Each row is a site, each column a condition, and each cell the number of trials on it — darker means more activity.

Other Trials in Narodny Onkologicky Ustav

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Trial Sponsor Phase Status Start Date End Date
A Randomized Open-Label Phase 3 Study of XL092 + Nivolumab vs Sunitinib in Subjects with Advanced or Metastatic Non-Clear Cell Renal Cell CarcinomaExelixis Inc.Phase IIINot Yet RecruitingJul 2023

IMP list

lock Showing 1 of 126 compounds — the rest is available on a paid plan.

IMP Trials Status First start Last start
Enzalutamide6Unknown2021-06-162026-03-24

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