Multispecialty hospital for active treatment Sveta Sofia EOOD
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Cardiovascular Diseases
The department investigates cardiovascular disease through trials that evaluate novel agents for heart attack prevention, blood pressure control, and heart failure management.
- Acute myocardial infarction
- Heart failure with preserved or mildly reduced ejection fraction
- Hypertension and high cardiovascular risk
- Hypercholesterolemia and triglyceride disorders
- Venous thromboembolism
The goal is to introduce safer, more effective therapies that lower cardiovascular events and improve quality of life.
Digestive System Diseases
Research in digestive system diseases targets inflammatory bowel conditions and related gastrointestinal disorders, testing treatments that induce remission and heal the intestinal lining.
- Ulcerative colitis
- Inflammatory bowel disease (moderate to severe)
- Cancer cachexia
- Colitis ulcerative
Studies aim to reduce flare‑ups, improve nutrient absorption, and support patients with chronic gut inflammation.
Eye Diseases
The site conducts trials on eye diseases to explore therapies that slow vision loss and restore retinal health.
- Geographic atrophy secondary to age‑related macular degeneration
Efforts focus on delivering treatments that preserve visual acuity and enhance daily functioning.
Hemic and Lymphatic Diseases
Investigations into hemic and lymphatic diseases include clotting disorders and platelet deficiencies, with a focus on safer prophylaxis and recovery.
- Severe hemophilia A and B
- Cancer‑associated thrombosis
- Chemotherapy‑induced thrombocytopenia
The aim is to prevent bleeding complications and reduce clot‑related risks in vulnerable patients.
Immune System Diseases
Trials addressing immune system diseases evaluate innovative immunomodulators for autoimmune conditions, seeking durable remission and symptom relief.
- Sjögren’s syndrome
- Systemic lupus erythematosus
- Rheumatoid arthritis
- Relapsing multiple sclerosis
- Alopecia areata
These studies strive to modulate immune activity without compromising overall health.
Musculoskeletal Diseases
The department explores treatments for musculoskeletal diseases, focusing on agents that reduce inflammation and preserve joint function.
- Rheumatoid arthritis
- Chronic joint pain associated with autoimmune disorders
Objectives include improving mobility and decreasing reliance on long‑term steroids.
Neoplasms
Oncology research at the hospital targets neoplasms, testing targeted therapies and immunotherapies across a spectrum of solid tumors.
- Advanced non‑small cell lung cancer with HER2 or EGFR mutations
- Melanoma (adjuvant setting)
- Head and neck squamous cell carcinoma
- Advanced solid malignancies
- Solid tumors undergoing chemotherapy
The purpose is to extend survival, delay progression, and improve post‑surgical outcomes.
Nervous System Diseases
Studies on nervous system diseases focus on demyelinating disorders, evaluating compounds that may lower relapse rates and protect neural tissue.
- Relapsing multiple sclerosis
Researchers aim to achieve longer remission periods and preserve neurological function.
Nutritional and Metabolic Diseases
Research in nutritional and metabolic diseases assesses lipid‑lowering agents and weight‑modulating therapies to address dyslipidemia and obesity.
- Hypertriglyceridemia and severe hypertriglyceridemia
- Hypercholesterolemia
- Obesity associated with heart failure
The goal is to reduce cardiovascular risk factors and support metabolic health.
Respiratory Tract Diseases
Clinical work on respiratory tract diseases evaluates inhaled and systemic treatments that improve lung function and reduce exacerbations.
- Chronic obstructive pulmonary disease (COPD)
- Mild asthma
- Non‑cystic fibrosis bronchiectasis with pathogenic bacteria
Trials seek to enhance breathing capacity, lower infection rates, and improve daily activity tolerance.
Skin and Connective Tissue Diseases
The department’s focus on skin and connective tissue diseases includes biologics aimed at reducing inflammation and skin lesions.
- Atopic dermatitis
- Plaque psoriasis
- Alopecia areata
Objectives are to achieve clearer skin, lessen itching, and improve patients’ self‑esteem.
Virus Diseases
Investigations into virus diseases target chronic viral infections, testing antiviral compounds for safety and viral suppression.
- Chronic hepatitis B virus infection
The aim is to achieve sustained viral load reduction and prevent liver disease progression.
Unspecified Therapeutic Areas
Additional studies at the site encompass a range of conditions that do not fit neatly into other categories, exploring innovative approaches across multiple systems.
- Cancer‑associated thrombosis in solid tumor patients
- Geographic atrophy related to age‑related macular degeneration
- Body‑weight loss in pancreatic cancer patients
These projects aim to fill therapeutic gaps and introduce novel treatment concepts.
Site Overview
Activity Indicator
Last 6 months
Trial Flow
How this site's trials are distributed across therapeutic areas and active substances (IMPs), and how they're positioned within their overall lifecycle status. Flow thickness represents the number of unique trials.
Top 4 of 11 therapeutic areas and 15 of 53 IMPs, ranked by number of trials.
Compounds & Molecules Timeline
The time span of clinical-trial activity for the main active substances (IMPs) studied at this site over the last 8 years. Each bar runs from the earliest trial start to the most recent end; a substance with a trial still open has no recorded end and is shown as ongoing.
Top 40 of 50 compounds, ranked by number of trials.
Sponsor & Partnership
Top sponsors by active trials, and the ones that have come back for more than one study.
Sponsor Network
Top 23 by active trials.
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Partnership History
Sponsors with repeated collaboration (≥ 2 trials).
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Sponsor Network Graph
How sponsors and therapeutic areas connect across this site's active trials: each link is at least one active trial shared between them, and bigger nodes mean more activity. Click a node to see its exact connections.
Country Benchmark
Compared to 476 other sites in Bulgaria
Therapeutic Area Benchmark — Bulgaria
Select a therapeutic area to compare against other sites in Bulgaria.
Competitor Comparison
Similar sites in the same country running a comparable number of trials (within ±30%), scored on how closely their trial portfolios match this one. Higher percentages mean a more similar profile.
Country: Bulgaria
Market Share
Country: Bulgaria
Therapeutic Area Market Share
Select a therapeutic area to view its disease coverage breakdown.
Heat Maps & Advanced Analytics
How often specific conditions appear in trials across this site and comparable sites from the same country. Each row is a site, each column a condition, and each cell the number of trials on it — darker means more activity.
Other Trials in Multispecialty hospital for active treatment Sveta Sofia EOOD
lock Showing 1 of 63 trials — the rest is available on a paid plan.
| Trial | Sponsor | Phase | Status | Start Date | End Date |
|---|---|---|---|---|---|
| (22153) Randomized, Double-Masked, Active-Controlled, Phase 3 Study of the Efficacy and Safety of Aflibercept 8 mg in Macular Edema Secondary to Retinal Vein Occlusion | Bayer AG | Phase III | Not Recruiting | Sep 2023 | May 2025 |
IMP list
lock Showing 1 of 53 compounds — the rest is available on a paid plan.
| IMP | Trials | Status | First start | Last start |
|---|---|---|---|---|
| Synthetic Double-Stranded Sirna Oligonucleotide Directed Against Apolipoprotein C-Iii Mrna And Covalently Linked To A Ligand Containing Three N-Acetylgalactosamine Residues | 4 | Unknown | 2024-10-31 | 2025-12-08 |
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