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Mental Health Center Sofia EOOD

Address
Bulevard Slivnitsa 309, 1202 Sofia, Bulgaria

Depression and Mood Disorders

The Mental Health Center Sofia EOOD conducts extensive studies on Major Depressive Disorder and related mood conditions, aiming to improve treatment options for patients who have not responded adequately to standard antidepressants.

  • Adjunctive novel compounds
  • Anhedonia‑targeted interventions
  • Anxious distress sub‑analyses
  • Long‑term safety extensions

Across 12 trials, eight investigators evaluate new therapeutic approaches, enhancing care for individuals with depression in Sofia, Bulgaria.

Schizophrenia and Psychotic Disorders

Research at the site focuses on Schizophrenia, testing adjunctive agents to reduce persistent symptoms and assess tolerability over extended periods.

  • Positive and Negative Syndrome Scale (PANSS) outcomes
  • Adjunctive antipsychotic strategies
  • Oral long‑acting formulations
  • Safety monitoring in chronic use

The department’s expertise in severe mental illness supports innovative trials that may reshape standard care for schizophrenia patients.

Neuropsychiatric Symptoms in Alzheimer’s Disease

A subset of studies addresses agitation linked to Alzheimer’s disease, evaluating rapid‑acting combinations to calm patients while maintaining safety.

  • CMAI‑IPA agitation scoring
  • Combination therapy with KarXT + KarX‑EC
  • Open‑label extension for durability
  • Safety profiling in elderly cohorts

These investigations broaden the Center’s portfolio beyond primary psychiatric disorders, reflecting a commitment to comprehensive behavioral health research.

Site Overview

assignment
24
connected trials
corporate_fare
15
sponsors
science
27
IMPs

Activity Indicator

Last 6 months

3
Trials started
-25% vs previous period.
4
Trials started 6–12 months ago
24
Total trials linked
Highly Active
trending_downDeclining-25%
1
1
1
Mar
Apr
May
Jun
Jul
Aug

Trial Flow

How this site's trials are distributed across therapeutic areas and active substances (IMPs), and how they're positioned within their overall lifecycle status. Flow thickness represents the number of unique trials.

Therapeutic areaarrow_forwardIMParrow_forwardLifecycle status

Top 2 of 3 therapeutic areas and 15 of 27 IMPs, ranked by number of trials.

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Compounds & Molecules Timeline

The time span of clinical-trial activity for the main active substances (IMPs) studied at this site over the last 8 years. Each bar runs from the earliest trial start to the most recent end; a substance with a trial still open has no recorded end and is shown as ongoing.

Trial span Ongoing Showing last 8 years
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Sponsor & Partnership

Top sponsors by active trials, and the ones that have come back for more than one study.

Active trials
11
Sponsors (total)
15
Active sponsors
10

Sponsor Network

Top 10 by active trials.

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Partnership History

Sponsors with repeated collaboration (≥ 2 trials).

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Sponsor Network Graph

How sponsors and therapeutic areas connect across this site's active trials: each link is at least one active trial shared between them, and bigger nodes mean more activity. Click a node to see its exact connections.

Country Benchmark

Compared to 476 other sites in Bulgaria

description
Trial volume
24
Outperforms 88% of sites
public
Therapeutic diversity
3areas
Outperforms 64% of sites
groups
Sponsor diversity
15sponsors
Outperforms 87% of sites

Therapeutic Area Benchmark — Bulgaria

Select a therapeutic area to compare against other sites in Bulgaria.

Competitor Comparison

Similar sites in the same country running a comparable number of trials (within ±30%), scored on how closely their trial portfolios match this one. Higher percentages mean a more similar profile.

Country: Bulgaria

Market Share

Country: Bulgaria

Therapeutic Area Market Share

Select a therapeutic area to view its disease coverage breakdown.

Heat Maps & Advanced Analytics

How often specific conditions appear in trials across this site and comparable sites from the same country. Each row is a site, each column a condition, and each cell the number of trials on it — darker means more activity.

Other Trials in Mental Health Center Sofia EOOD

lock Showing 1 of 24 trials — the rest is available on a paid plan.

Trial Sponsor Phase Status Start Date End Date
A Phase 2 Randomized, Double-Blind, Placebo-Controlled Study to Evaluate the Efficacy and Safety of DT-101 in Adults with Major Depressive DisorderDraig Therapeutics LimitedPhase IIRecruitingMar 2026

IMP list

lock Showing 1 of 27 compounds — the rest is available on a paid plan.

IMP Trials Status First start Last start
Trospium Chloride4Unknown2023-03-222026-06-01

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