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Medical Institute Ministry Of Interior

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Cardiovascular Disease Research

The Neurology Clinic at Medical Institute Ministry Of Interior is conducting studies focused on cardiovascular disease, evaluating new treatments aimed at reducing clot formation and preventing major adverse cardiac events.

  • Evaluation of novel anticoagulant therapy
  • Safety assessment of cardiovascular agents
  • Impact on major adverse cardiovascular events

These trials support the institute’s commitment to advancing heart health in the Sofia region.

Multiple Sclerosis Investigations

Researchers are exploring innovative oral therapies for relapsing multiple sclerosis and progressive multiple sclerosis, with goals to lower relapse rates and slow brain atrophy.

  • Efficacy measured by MRI lesion count
  • Relapse prevention strategies
  • Neuroprotective outcomes in progressive disease

The site’s neurologists aim to improve quality of life for patients living with MS.

Diabetes Management Studies

The clinic is testing a once‑weekly insulin analogue for adults with type 2 diabetes, seeking comparable blood‑sugar control to daily basal insulin while simplifying treatment.

  • Glycaemic control comparison
  • Patient‑reported outcomes
  • Long‑term safety monitoring

Findings may help reduce daily injection burden for diabetic patients across Bulgaria.

Chronic Rhinosinusitis Research

A trial evaluates the biologic agent tezepelumab in individuals with chronic rhinosinusitis with nasal polyposis, aiming to lessen nasal congestion and improve sinus symptoms.

  • Symptom score reduction
  • Quality‑of‑life improvements
  • Safety profile of biologic therapy

This work expands the institute’s expertise beyond neurology into ENT conditions.

Respiratory Health Initiatives

While primarily a neurology center, the institute also supports studies addressing respiratory tract diseases, focusing on innovative approaches to manage airway inflammation.

  • Evaluation of anti‑inflammatory agents
  • Pulmonary function outcomes
  • Integration with systemic disease management

Collaborative efforts with pulmonology specialists enhance comprehensive patient care.

Site Overview

assignment
10
connected trials
corporate_fare
6
sponsors
science
14
IMPs

Activity Indicator

Last 6 months

1
Trials started
New activity detected vs previous period.
0
Trials started 6–12 months ago
10
Total trials linked
Highly Active
trending_upGrowing+100%
1
Mar
Apr
May
Jun
Jul
Aug

Trial Flow

How this site's trials are distributed across therapeutic areas and active substances (IMPs), and how they're positioned within their overall lifecycle status. Flow thickness represents the number of unique trials.

Therapeutic areaarrow_forwardIMParrow_forwardLifecycle status

Top 5 of 6 therapeutic areas and 14 IMPs, ranked by number of trials.

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Compounds & Molecules Timeline

The time span of clinical-trial activity for the main active substances (IMPs) studied at this site over the last 8 years. Each bar runs from the earliest trial start to the most recent end; a substance with a trial still open has no recorded end and is shown as ongoing.

Trial span Ongoing Showing last 8 years
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Sponsor & Partnership

Top sponsors by active trials, and the ones that have come back for more than one study.

Active trials
5
Sponsors (total)
6
Active sponsors
4

Sponsor Network

Top 4 by active trials.

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Partnership History

Sponsors with repeated collaboration (≥ 2 trials).

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Sponsor Network Graph

How sponsors and therapeutic areas connect across this site's active trials: each link is at least one active trial shared between them, and bigger nodes mean more activity. Click a node to see its exact connections.

Country Benchmark

Compared to 476 other sites in Bulgaria

description
Trial volume
10
Outperforms 72% of sites
public
Therapeutic diversity
6areas
Outperforms 84% of sites
groups
Sponsor diversity
6sponsors
Outperforms 68% of sites

Therapeutic Area Benchmark — Bulgaria

Select a therapeutic area to compare against other sites in Bulgaria.

Competitor Comparison

Similar sites in the same country running a comparable number of trials (within ±30%), scored on how closely their trial portfolios match this one. Higher percentages mean a more similar profile.

Country: Bulgaria

Market Share

Country: Bulgaria

Therapeutic Area Market Share

Select a therapeutic area to view its disease coverage breakdown.

Heat Maps & Advanced Analytics

How often specific conditions appear in trials across this site and comparable sites from the same country. Each row is a site, each column a condition, and each cell the number of trials on it — darker means more activity.

Other Trials in Medical Institute Ministry Of Interior

lock Showing 1 of 10 trials — the rest is available on a paid plan.

Trial Sponsor Phase Status Start Date End Date
A Phase 3, Multicenter, Randomized, Double-Blind Study to Evaluate the Safety and Efficacy of Contezolid Acefosamil and Contezolid Compared to Linezolid Administered Intravenously and Orally to Adults with Moderate or Severe Diabetic Foot InfectionsMicurx Pharmaceuticals Inc.Phase IIIRecruitingMar 2023

IMP list

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IMP Trials Status First start Last start
Vidofludimus Calcium3Unknown2019-01-232022-03-01

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