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Maastro

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Analytical, Diagnostic and Therapeutic Techniques and Equipment – Therapeutics

The Radiation Oncology department at Maastro leverages cutting‑edge imaging and precision radiotherapy tools to enhance treatment effectiveness for cancer patients.

  • Neoadjuvant triple therapy combining chemotherapy, immunotherapy, and stereotactic ablative radiotherapy for pancreatic cancer
  • Targeted radiotherapy with short‑term hormonal treatment for oligometastatic prostate disease
  • Co‑analgesic methadone trial for metastatic bone pain management

By integrating innovative equipment with multidisciplinary expertise, the team aims to translate technological advances into tangible clinical benefits.

Analytical, Diagnostic, Therapeutic Techniques and Equipment – Surgical Procedures, Operative

Collaboration between surgeons and radiation oncologists at Maastro focuses on organ‑preserving strategies and optimal surgical margins for gastrointestinal tumors.

  • Rectal preserving therapy after local excision versus adjuvant chemoradiotherapy
  • Radical surgery compared with adjuvant treatment for early rectal cancer
  • Evaluating clear resection margins in borderline resectable pancreatic cancer

The interdisciplinary approach seeks to balance curative intent with quality‑of‑life considerations for patients undergoing operative procedures.

Diseases – Digestive System Diseases

Clinical studies at Maastro target major digestive malignancies, exploring neoadjuvant regimens and targeted therapies to improve survival outcomes.

  • Neoadjuvant treatment for borderline resectable pancreatic cancer
  • Adding trastuzumab and pertuzumab to chemoradiation for HER2‑positive esophageal adenocarcinoma
  • High‑risk locally advanced rectal cancer protocols comparing FOLFOXIRI and CAPOX/FOLFOX

These trials aim to refine therapeutic pathways and increase the proportion of patients achieving disease‑free status after treatment.

Diseases – Neoplasms

The research portfolio at Maastro encompasses a broad spectrum of solid tumors, with emphasis on molecular profiling and symptom control.

  • Molecularly guided adjuvant therapy for mismatch‑repair deficient high‑risk endometrial cancer
  • Pain reduction strategies for patients with bone metastasis
  • Metastasis‑directed radiotherapy combined with androgen deprivation therapy for oligometastatic prostate cancer

By addressing both tumor biology and patient comfort, the program contributes to comprehensive cancer care.

Diseases – Pathological Conditions, Signs and Symptoms

Patient‑centered investigations at Maastro focus on improving symptom management and monitoring disease recurrence across cancer types.

  • Evaluating methadone as an add‑on to opioids for metastatic bone pain
  • Assessing three‑year recurrence‑free survival in endometrial cancer patients
  • Measuring clinical complete response rates after neoadjuvant chemoradiotherapy for rectal cancer

The goal is to enhance quality of life while providing reliable metrics for long‑term treatment success.

Site Overview

assignment
10
connected trials
corporate_fare
6
sponsors
science
18
IMPs

Activity Indicator

Last 6 months

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Trials started
-100% vs previous period.
2
Trials started 6–12 months ago
10
Total trials linked
Highly Active
trending_downDeclining-100%
Mar
Apr
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Trial Flow

How this site's trials are distributed across therapeutic areas and active substances (IMPs), and how they're positioned within their overall lifecycle status. Flow thickness represents the number of unique trials.

Therapeutic areaarrow_forwardIMParrow_forwardLifecycle status

Top 5 therapeutic areas and 15 of 18 IMPs, ranked by number of trials.

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Compounds & Molecules Timeline

The time span of clinical-trial activity for the main active substances (IMPs) studied at this site over the last 8 years. Each bar runs from the earliest trial start to the most recent end; a substance with a trial still open has no recorded end and is shown as ongoing.

Trial span Ongoing Showing last 8 years
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Sponsor & Partnership

Top sponsors by active trials, and the ones that have come back for more than one study.

Active trials
7
Sponsors (total)
6
Active sponsors
4

Sponsor Network

Top 4 by active trials.

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Partnership History

Sponsors with repeated collaboration (≥ 2 trials).

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Sponsor Network Graph

How sponsors and therapeutic areas connect across this site's active trials: each link is at least one active trial shared between them, and bigger nodes mean more activity. Click a node to see its exact connections.

Country Benchmark

Compared to 271 other sites in The Netherlands

description
Trial volume
10
Outperforms 69% of sites
public
Therapeutic diversity
5areas
Outperforms 69% of sites
groups
Sponsor diversity
6sponsors
Outperforms 66% of sites

Therapeutic Area Benchmark — The Netherlands

Select a therapeutic area to compare against other sites in The Netherlands.

Competitor Comparison

Similar sites in the same country running a comparable number of trials (within ±30%), scored on how closely their trial portfolios match this one. Higher percentages mean a more similar profile.

Country: The Netherlands

Market Share

Country: The Netherlands

Therapeutic Area Market Share

Select a therapeutic area to view its disease coverage breakdown.

Heat Maps & Advanced Analytics

How often specific conditions appear in trials across this site and comparable sites from the same country. Each row is a site, each column a condition, and each cell the number of trials on it — darker means more activity.

Other Trials in Maastro

lock Showing 1 of 10 trials — the rest is available on a paid plan.

Trial Sponsor Phase Status Start Date End Date
Evaluation of Durvalumab as Adjuvant Therapy in Mismatch Repair-Deficient High-Risk Endometrial Cancer Post-Surgery: A Phase III Clinical TrialLeids Universitair Medisch Centrum (LUMC)Phase IIIRecruitingJun 2022

IMP list

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IMP Trials Status First start Last start
Oxaliplatin5Unknown2017-10-092026-03-11

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