Laenssjukhuset I Kalmar Region Kalmar Laen
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Analytical, Diagnostic & Therapeutic Techniques – Operative Surgery
At Laenssjukhuset I Kalmar Region Kalmar Laen, pediatric surgeons are evaluating new operative tools and diagnostic approaches to improve outcomes for children undergoing complex procedures.
- Antibiotic‑impregnated bone graft for hip arthroplasty
- Therapeutic drug monitoring of kloxacillin in S. aureus bacteremia
- Tumor treating fields combined with chemotherapy for glioblastoma
- Enhanced imaging techniques for early disease detection
The department currently supports 10 active trials led by 10 investigators, reflecting a strong commitment to innovative surgical care.
Bacterial Infections & Mycoses
Clinical research focuses on combating resistant bacterial strains, aiming to identify safer oral regimens and infection‑preventing strategies for conditions such as Staphylococcus aureus bacteremia.
- Multidrug‑resistant urinary tract infections
- Prosthetic joint infection prevention
- S. aureus bacteremia dosing study with kloxacillin
- Extended‑spectrum beta‑lactamase urinary infections
These studies seek to reduce antibiotic resistance and improve pediatric infection management.
Hemic & Lymphatic Diseases
Trials target lymphoid malignancies, evaluating novel antibody‑based combinations to enhance remission rates in young patients with diseases like follicular lymphoma.
- Follicular lymphoma treatment with rituximab‑lenalidomide‑tafasitamab
- Mantle cell lymphoma therapy with acalabrutinib‑rituximab
- Biomarker‑driven therapy in metastatic prostate cancer
Research integrates molecular profiling to personalize therapy across hematologic cancers.
Immune System Disorders
Investigations assess complement inhibition as a strategy to protect kidney function in rare immune‑mediated conditions such as C3 glomerulopathy.
- Aliskiren versus enalapril in C3 glomerulopathy
- Complement activation monitoring in renal disease
- Biomarker‑guided dosing adjustments for renal protection
Outcomes may reshape standard care for complement‑mediated kidney disease.
Musculoskeletal Disorders
Research evaluates surgical adjuncts and rehabilitation methods to lower infection risk and enhance joint recovery, addressing challenges such as prosthetic joint infection.
- Antibiotic‑impregnated bone graft in hip replacement
- Post‑operative infection surveillance protocols
- Functional outcome measures after orthopedic surgery
The program aligns with the department’s focus on safe musculoskeletal interventions for children.
Neoplasms (Cancer)
A broad oncology portfolio examines immunotherapy duration, combined chemoradiation, and targeted agents across several pediatric malignancies, including glioblastoma and cutaneous malignant melanoma.
- Short‑course immunotherapy for high‑risk melanoma
- TMZ/LOM versus TMZ alone in MGMT‑methylated glioblastoma
- Acalabrutinib‑rituximab in mantle cell lymphoma
- Tafasitamab addition for follicular lymphoma
- Biomarker‑driven treatment in metastatic prostate cancer
These trials aim to improve survival and reduce treatment toxicity for pediatric cancer patients.
Nervous System Disorders
Studies address acute neurological injuries and brain tumors, testing neuroprotective drugs and innovative radiotherapy adjuncts for conditions such as facial nerve palsy and glioblastoma.
- Cortisone therapy for acute facial nerve palsy
- Tumor treating fields with chemotherapy for glioblastoma
- Neuro‑physiological monitoring in postoperative care
Efforts focus on preserving function and enhancing quality of life for affected children.
Pathological Conditions & Symptoms
Research includes symptom‑focused assessments, such as recovery scales after nerve injury and quality‑of‑life metrics in infection trials, exemplified by studies on facial nerve palsy.
- House‑Brackmann scale outcomes for facial palsy
- Patient‑reported outcomes in infection trials
- Biomarker‑based symptom tracking across diseases
Patient‑centered endpoints guide therapeutic decisions throughout the site’s portfolio.
Musculoskeletal & Neural Physiology
Investigations explore physiological responses to surgical implants and neuro‑rehabilitation, informing device design and therapy timing for pediatric patients.
- Bone graft integration studies
- Neural plasticity after facial nerve repair
- Biomechanical analysis of joint prostheses
Findings support evidence‑based refinement of pediatric surgical practice at the Kalmar site.
Site Overview
Activity Indicator
Last 6 months
Trial Flow
How this site's trials are distributed across therapeutic areas and active substances (IMPs), and how they're positioned within their overall lifecycle status. Flow thickness represents the number of unique trials.
Top 5 of 11 therapeutic areas and 15 of 36 IMPs, ranked by number of trials.
Compounds & Molecules Timeline
The time span of clinical-trial activity for the main active substances (IMPs) studied at this site over the last 8 years. Each bar runs from the earliest trial start to the most recent end; a substance with a trial still open has no recorded end and is shown as ongoing.
Sponsor & Partnership
Top sponsors by active trials, and the ones that have come back for more than one study.
Sponsor Network
Top 13 by active trials.
- 1Region Skane2active
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Partnership History
Sponsors with repeated collaboration (≥ 2 trials).
- 1Region Skane4trials
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Sponsor Network Graph
How sponsors and therapeutic areas connect across this site's active trials: each link is at least one active trial shared between them, and bigger nodes mean more activity. Click a node to see its exact connections.
Country Benchmark
Compared to 188 other sites in Sweden
Therapeutic Area Benchmark — Sweden
Select a therapeutic area to compare against other sites in Sweden.
Competitor Comparison
Similar sites in the same country running a comparable number of trials (within ±30%), scored on how closely their trial portfolios match this one. Higher percentages mean a more similar profile.
Country: Sweden
Market Share
Country: Sweden
Therapeutic Area Market Share
Select a therapeutic area to view its disease coverage breakdown.
Heat Maps & Advanced Analytics
How often specific conditions appear in trials across this site and comparable sites from the same country. Each row is a site, each column a condition, and each cell the number of trials on it — darker means more activity.
Other Trials in Laenssjukhuset I Kalmar Region Kalmar Laen
lock Showing 1 of 14 trials — the rest is available on a paid plan.
| Trial | Sponsor | Phase | Status | Start Date | End Date |
|---|---|---|---|---|---|
| Comparative Study of Short vs. Long Adjuvant Pembrolizumab and Nivolumab Therapy Post-Radical Surgery in Stage IIb-IV Cutaneous Malignant Melanoma | North Estonia Medical Centre Foundation, Rigas Austrumu kliniska universitates slimnica SIA, Universita' Degli Studi Di Perugia, Uppsala University Hospital, Vilniaus universiteto ligonine Santaros klinikos VšĮ | Phase III | Recruiting | Nov 2024 | — |
IMP list
lock Showing 1 of 36 compounds — the rest is available on a paid plan.
| IMP | Trials | Status | First start | Last start |
|---|---|---|---|---|
| Rituximab | 2 | Unknown | 2020-08-18 | 2025-05-27 |
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