local_hospital

L’Hopital Alexandra Lepeve

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Digestive System Diseases

At L’Hopital Alexandra Lepeve, investigators are conducting studies aimed at improving outcomes for patients with severe alcohol‑related liver injury. The trials evaluate novel therapeutic regimens that combine antioxidants with standard corticosteroid therapy to increase survival and liver function recovery.

  • Alcoholic hepatitis

The department currently runs several trials in this area, contributing to the overall portfolio of 18 studies at the site.

Hemic and Lymphatic Diseases

Research in the hematology department targets a broad spectrum of blood‑borne malignancies, including acute leukemias and aggressive lymphomas. Clinical programs test cutting‑edge immunotherapies, stem‑cell transplantation strategies, and minimal residual disease‑guided approaches to boost long‑term remission rates.

  • Acute myeloid leukemia
  • Diffuse Large B‑Cell Lymphoma
  • Peripheral T‑Cell Lymphoma
  • Multiple Myeloma

Seven investigators lead these efforts, reflecting the site’s strong commitment to advancing care for patients with hematologic cancers.

Immune System Diseases

Trials focusing on autoimmune blood disorders evaluate innovative biologic combinations designed to restore normal platelet production. The studies compare a subcutaneous belimumab plus rituximab regimen with standard therapy, seeking faster and more durable responses in chronic immune thrombocytopenia.

  • Immune thrombocytopenia (ITP)

This work adds a valuable dimension to the site’s clinical research portfolio, addressing unmet needs in immune‑mediated disease.

Neoplasms

Oncology investigations at the center include advanced solid tumors and large‑cell lymphomas, with a focus on immune checkpoint inhibition and antibody‑drug conjugates. Researchers assess whether adding radiotherapy to PD‑1 blockade or combining novel agents with standard chemotherapy can extend survival in patients with stage III/IV disease.

  • Advanced non‑small cell lung cancer
  • Large B‑Cell Lymphoma
  • Follicular Lymphoma

The site’s multidisciplinary team collaborates with national cancer networks to bring these innovative protocols to the Dunkirk region.

Nervous System Diseases

A placebo‑controlled study evaluates the impact of a 30‑week caffeine regimen on cognitive decline in early‑to‑moderate Alzheimer’s disease. The trial measures changes in memory and executive function to determine whether a simple dietary intervention can slow disease progression.

  • Alzheimer’s disease

This investigation highlights the department’s commitment to exploring accessible treatments for neurodegenerative conditions.

Site Overview

assignment
19
connected trials
corporate_fare
12
sponsors
science
49
IMPs

Activity Indicator

Last 6 months

2
Trials started
0% vs previous period.
2
Trials started 6–12 months ago
19
Total trials linked
Highly Active
trending_flatStable0%
1
1
Mar
Apr
May
Jun
Jul
Aug

Trial Flow

How this site's trials are distributed across therapeutic areas and active substances (IMPs), and how they're positioned within their overall lifecycle status. Flow thickness represents the number of unique trials.

Therapeutic areaarrow_forwardIMParrow_forwardLifecycle status

Top 4 of 5 therapeutic areas and 15 of 49 IMPs, ranked by number of trials.

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Compounds & Molecules Timeline

The time span of clinical-trial activity for the main active substances (IMPs) studied at this site over the last 8 years. Each bar runs from the earliest trial start to the most recent end; a substance with a trial still open has no recorded end and is shown as ongoing.

Trial span Ongoing Showing last 8 years

Top 40 of 44 compounds, ranked by number of trials.

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Sponsor & Partnership

Top sponsors by active trials, and the ones that have come back for more than one study.

Active trials
12
Sponsors (total)
12
Active sponsors
9

Sponsor Network

Top 9 by active trials.

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Partnership History

Sponsors with repeated collaboration (≥ 2 trials).

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Sponsor Network Graph

How sponsors and therapeutic areas connect across this site's active trials: each link is at least one active trial shared between them, and bigger nodes mean more activity. Click a node to see its exact connections.

Country Benchmark

Compared to 978 other sites in France

description
Trial volume
19
Outperforms 80% of sites
public
Therapeutic diversity
5areas
Outperforms 73% of sites
groups
Sponsor diversity
12sponsors
Outperforms 79% of sites

Therapeutic Area Benchmark — France

Select a therapeutic area to compare against other sites in France.

Competitor Comparison

Similar sites in the same country running a comparable number of trials (within ±30%), scored on how closely their trial portfolios match this one. Higher percentages mean a more similar profile.

Country: France

Market Share

Country: France

Therapeutic Area Market Share

Select a therapeutic area to view its disease coverage breakdown.

Heat Maps & Advanced Analytics

How often specific conditions appear in trials across this site and comparable sites from the same country. Each row is a site, each column a condition, and each cell the number of trials on it — darker means more activity.

Other Trials in L’Hopital Alexandra Lepeve

lock Showing 1 of 19 trials — the rest is available on a paid plan.

Trial Sponsor Phase Status Start Date End Date
Efficacy and Safety of Etentamig and Daratumumab Versus Daratumumab and Combination Therapy in Transplant-Ineligible Patients With Newly Diagnosed Multiple MyelomaAbbVie Deutschland GmbH & Co. KGPhase IVRecruitingFeb 2026

IMP list

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IMP Trials Status First start Last start
Dexamethasone7Unknown2019-10-072026-06-12

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