local_hospital

Krajska nemocnice Liberec a.s.

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Bacterial Infections and Mycoses

The department is conducting trials that assess antibiotic optimization for serious bacterial infections, aiming to improve cure rates and reduce resistance.

  • Clostridioides difficile infection
  • Complicated urinary tract infection
  • Acute uncomplicated pyelonephritis

Krajska nemocnice Liberec a.s. supports these studies through its specialized infectious‑disease unit.

Cardiovascular Diseases

Research efforts focus on stroke prevention after non‑cardioembolic events and on improving outcomes for patients with acute heart failure.

  • Acute ischemic stroke
  • High‑risk transient ischemic attack
  • Acute heart failure

The Neurologický JIP A unit collaborates closely with cardiology to enroll eligible participants.

Digestive System Diseases

Ongoing studies evaluate novel agents for chronic liver conditions, targeting liver disease therapies that may halt progression and improve liver function.

  • Metabolic Dysfunction‑Associated Steatotic Liver Disease
  • Non‑alcoholic steatohepatitis
  • Primary Biliary Cholangitis

The hospital’s gastroenterology team provides comprehensive care for trial participants.

Female Urogenital Diseases and Pregnancy Complications

Trials in this area explore bladder cancer treatment options for patients with non‑muscle‑invasive disease, including immunotherapy and gene‑based approaches.

  • High‑risk BCG‑unresponsive non‑muscle‑invasive bladder cancer
  • Intermediate risk non‑muscle invasive bladder cancer
  • Non‑muscle invasive bladder cancer with carcinoma in situ

The urology department at Krajska nemocnice Liberec a.s. coordinates patient screening and follow‑up.

Male Urogenital Diseases

Investigators are testing new hormonal and targeted strategies to improve survival in men with advanced prostate cancer, emphasizing prostate cancer therapy.

  • Metastatic castration‑resistant prostate cancer

Urologists at the site contribute expertise in disease staging and treatment monitoring.

Neoplasms

A broad oncology portfolio includes studies on breast, lung, and other solid tumors, seeking to enhance outcomes with advanced cancer immunotherapy and targeted combinations.

  • Triple‑negative breast cancer
  • Hormone‑receptor positive HER2‑negative advanced breast cancer
  • Non‑small cell lung cancer
  • Small cell lung cancer
  • Metastatic castration‑resistant prostate cancer

The comprehensive cancer center at Krajska nemocnice Liberec a.s. enables multidisciplinary trial participation.

Nutritional and Metabolic Diseases

Studies target metabolic liver injury and related disorders, evaluating agents that may reverse steatosis and improve metabolic health, highlighted by metabolic disease research.

  • Non‑alcoholic steatohepatitis
  • Metabolic Dysfunction‑Associated Steatotic Liver Disease
  • Nutritional metabolic disorders

Endocrinology specialists support patient enrollment and metabolic assessments.

Virus Diseases

Clinical programs investigate therapies for chronic viral hepatitis, aiming to achieve viral clearance and liver health, with a focus on viral hepatitis treatment.

  • Chronic hepatitis D infection
  • Chronic hepatitis B infection

Infectious disease clinicians at the hospital oversee virologic monitoring.

Other Research Areas

Additional projects explore innovative combinations of immunotherapy, targeted agents, and gene‑based therapies across various cancers, reflecting the site’s commitment to innovative therapeutic approaches.

  • Combination immunotherapy trials
  • Novel targeted agents
  • Gene‑based intravesical therapies

The multidisciplinary team at Krajska nemocnice Liberec a.s. facilitates rapid translation of emerging treatments.

Site Overview

assignment
40
connected trials
corporate_fare
24
sponsors
science
107
IMPs

Activity Indicator

Last 6 months

0
Trials started
-100% vs previous period.
3
Trials started 6–12 months ago
40
Total trials linked
Highly Active
trending_downDeclining-100%
Mar
Apr
May
Jun
Jul
Aug

Trial Flow

How this site's trials are distributed across therapeutic areas and active substances (IMPs), and how they're positioned within their overall lifecycle status. Flow thickness represents the number of unique trials.

Therapeutic areaarrow_forwardIMParrow_forwardLifecycle status

Top 4 of 12 therapeutic areas and 15 of 107 IMPs, ranked by number of trials.

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Compounds & Molecules Timeline

The time span of clinical-trial activity for the main active substances (IMPs) studied at this site over the last 8 years. Each bar runs from the earliest trial start to the most recent end; a substance with a trial still open has no recorded end and is shown as ongoing.

Trial span Ongoing Showing last 8 years

Top 40 of 107 compounds, ranked by number of trials.

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Sponsor & Partnership

Top sponsors by active trials, and the ones that have come back for more than one study.

Active trials
14
Sponsors (total)
24
Active sponsors
13

Sponsor Network

Top 13 by active trials.

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Partnership History

Sponsors with repeated collaboration (≥ 2 trials).

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Sponsor Network Graph

How sponsors and therapeutic areas connect across this site's active trials: each link is at least one active trial shared between them, and bigger nodes mean more activity. Click a node to see its exact connections.

Country Benchmark

Compared to 634 other sites in Czechia

description
Trial volume
40
Outperforms 95% of sites
public
Therapeutic diversity
12areas
Outperforms 97% of sites
groups
Sponsor diversity
24sponsors
Outperforms 96% of sites

Therapeutic Area Benchmark — Czechia

Select a therapeutic area to compare against other sites in Czechia.

Competitor Comparison

Similar sites in the same country running a comparable number of trials (within ±30%), scored on how closely their trial portfolios match this one. Higher percentages mean a more similar profile.

Country: Czechia

Market Share

Country: Czechia

Therapeutic Area Market Share

Select a therapeutic area to view its disease coverage breakdown.

Heat Maps & Advanced Analytics

How often specific conditions appear in trials across this site and comparable sites from the same country. Each row is a site, each column a condition, and each cell the number of trials on it — darker means more activity.

Other Trials in Krajska nemocnice Liberec a.s.

lock Showing 1 of 40 trials — the rest is available on a paid plan.

Trial Sponsor Phase Status Start Date End Date
A Phase 2b Randomized, Double-Blind Placebo-Controlled, Multicenter Study to Evaluate the Efficacy and Safety of Efinopegdutide (MK-6024) in Adults with Precirrhotic Nonalcoholic SteatohepatitisMerck Sharp & Dohme LLCPhase IINot RecruitingSep 2023Dec 2025

IMP list

lock Showing 1 of 107 compounds — the rest is available on a paid plan.

IMP Trials Status First start Last start
Pembrolizumab4Unknown2020-06-092025-11-10

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