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Klinikum Frankfurt Hoechst GmbH

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Klinikum Frankfurt Hoechst GmbH - Breast Cancer Research Center

Klinikum Frankfurt Hoechst GmbH is a leading clinical research institution with extensive expertise in oncology clinical trials, particularly focusing on breast cancer therapeutics. The center demonstrates comprehensive capabilities in evaluating novel treatment approaches across all breast cancer subtypes, from early-stage disease through advanced and metastatic presentations.

  • Triple-negative breast cancer (TNBC) neoadjuvant and adjuvant immunotherapy trials
  • Hormone receptor-positive/HER2-negative breast cancer with targeted therapies including CDK4/6 inhibitors and PARP inhibitors
  • HER2-positive breast cancer studies evaluating antibody-drug conjugates and personalized treatment strategies
  • Gastrointestinal malignancies including gastric and gastroesophageal junction adenocarcinomas, and ovarian cancer research

The center's portfolio includes pivotal phase II and III studies investigating precision medicine approaches with biomarker-driven patient selection, including germline BRCA mutations, PIK3CA alterations, and NPM1-mutated acute myeloid leukemia. Their research encompasses innovative combination strategies with immunotherapies, targeted agents, and chemotherapy, with particular emphasis on adjuvant and neoadjuvant treatment optimization to improve disease-free survival and overall outcomes in high-risk patient populations.

Site Overview

assignment
27
connected trials
corporate_fare
25
sponsors
science
57
IMPs

Activity Indicator

Last 6 months

1
Trials started
-75% vs previous period.
4
Trials started 6–12 months ago
27
Total trials linked
Highly Active
trending_downDeclining-75%
1
Mar
Apr
May
Jun
Jul
Aug

Trial Flow

How this site's trials are distributed across therapeutic areas and active substances (IMPs), and how they're positioned within their overall lifecycle status. Flow thickness represents the number of unique trials.

Therapeutic areaarrow_forwardIMParrow_forwardLifecycle status

Top 3 of 4 therapeutic areas and 15 of 57 IMPs, ranked by number of trials.

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Compounds & Molecules Timeline

The time span of clinical-trial activity for the main active substances (IMPs) studied at this site over the last 8 years. Each bar runs from the earliest trial start to the most recent end; a substance with a trial still open has no recorded end and is shown as ongoing.

Trial span Ongoing Showing last 8 years

Top 40 of 56 compounds, ranked by number of trials.

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Sponsor & Partnership

Top sponsors by active trials, and the ones that have come back for more than one study.

Active trials
16
Sponsors (total)
25
Active sponsors
16

Sponsor Network

Top 16 by active trials.

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Partnership History

Sponsors with repeated collaboration (≥ 2 trials).

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Sponsor Network Graph

How sponsors and therapeutic areas connect across this site's active trials: each link is at least one active trial shared between them, and bigger nodes mean more activity. Click a node to see its exact connections.

Country Benchmark

Compared to 2 161 other sites in Germany

description
Trial volume
27
Outperforms 93% of sites
public
Therapeutic diversity
4areas
Outperforms 86% of sites
groups
Sponsor diversity
25sponsors
Outperforms 95% of sites

Therapeutic Area Benchmark — Germany

Select a therapeutic area to compare against other sites in Germany.

Competitor Comparison

Similar sites in the same country running a comparable number of trials (within ±30%), scored on how closely their trial portfolios match this one. Higher percentages mean a more similar profile.

Country: Germany

Market Share

Country: Germany

Therapeutic Area Market Share

Select a therapeutic area to view its disease coverage breakdown.

Heat Maps & Advanced Analytics

How often specific conditions appear in trials across this site and comparable sites from the same country. Each row is a site, each column a condition, and each cell the number of trials on it — darker means more activity.

Other Trials in Klinikum Frankfurt Hoechst GmbH

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Trial Sponsor Phase Status Start Date End Date
A phase 2b, multinational, randomized, double-blind study to investigate the efficacy and safety of redasemtide (S-005151) compared with placebo in adult participants with acute ischemic strokeShionogi B.V.Phase IINot Yet RecruitingFeb 2024Jun 2026

IMP list

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IMP Trials Status First start Last start
Anastrozole3Unknown2019-06-142025-03-24

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