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Klinika za psihijatriju Vrapce

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Nervous System Diseases

The Department for Biological Psychiatry and Psychogeriatrics at Klinika za psihijatriju Vrapce concentrates on neurodegenerative conditions that affect the brain’s structure and function.

  • Evaluation of agitation in patients with Alzheimer’s dementia
  • Study of psychosis linked to Alzheimer’s disease
  • Assessment of cognitive decline in mild to moderate Alzheimer’s disease
  • Investigation of long‑term safety of novel agents for cognitive impairment in Alzheimer’s patients

These trials aim to test new therapies that reduce behavioral symptoms, improve cognition, and verify long‑term tolerability in elderly populations.

Behavioral Disciplines and Activities

Research here targets disruptive behaviors that compromise daily living and caregiver burden.

  • Trials addressing agitation associated with Alzheimer’s dementia
  • Interventions for mania in Bipolar‑I disorder
  • Adjunctive treatment of tardive dyskinesia in individuals with schizophrenia or related mood disorders
  • Evaluation of agents for psychosis associated with Alzheimer’s disease

The purpose is to identify effective medications that calm agitation, control manic episodes, and lessen involuntary movements, thereby enhancing patient safety and quality of life.

Mental Disorders

The site conducts extensive work on core psychiatric illnesses that require long‑term management.

  • Studies on symptom relief in schizophrenia
  • Evaluation of acute treatment for Manic episodes in Bipolar I Disorder
  • Adjunctive therapy trials for Major Depressive Disorder
  • Research on overlapping conditions such as schizoaffective disorder

Objectives include testing novel compounds for efficacy, monitoring safety, and improving overall functional outcomes for patients with severe mental illness.

Psychological Phenomena

This field explores underlying mental processes that manifest as clinical symptoms.

  • Measurement of agitation using standardized inventories
  • Quantification of psychosis severity through clinician‑rated scales
  • Assessment of cognitive impairment and global functioning in dementia
  • Monitoring of motor disturbances such as tardive dyskinesia

The trials seek to refine diagnostic criteria, evaluate therapeutic impact on these phenomena, and support better clinical decision‑making.

Site Overview

assignment
16
connected trials
corporate_fare
9
sponsors
science
11
IMPs

Activity Indicator

Last 6 months

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Trials started
-100% vs previous period.
1
Trials started 6–12 months ago
16
Total trials linked
Highly Active
trending_downDeclining-100%
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Trial Flow

How this site's trials are distributed across therapeutic areas and active substances (IMPs), and how they're positioned within their overall lifecycle status. Flow thickness represents the number of unique trials.

Therapeutic areaarrow_forwardIMParrow_forwardLifecycle status
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Compounds & Molecules Timeline

The time span of clinical-trial activity for the main active substances (IMPs) studied at this site over the last 8 years. Each bar runs from the earliest trial start to the most recent end; a substance with a trial still open has no recorded end and is shown as ongoing.

Trial span Ongoing Showing last 8 years
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Sponsor & Partnership

Top sponsors by active trials, and the ones that have come back for more than one study.

Active trials
11
Sponsors (total)
9
Active sponsors
6

Sponsor Network

Top 6 by active trials.

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Partnership History

Sponsors with repeated collaboration (≥ 2 trials).

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Sponsor Network Graph

How sponsors and therapeutic areas connect across this site's active trials: each link is at least one active trial shared between them, and bigger nodes mean more activity. Click a node to see its exact connections.

Country Benchmark

Compared to 60 other sites in Croatia

description
Trial volume
16
Outperforms 77% of sites
public
Therapeutic diversity
4areas
Outperforms 67% of sites
groups
Sponsor diversity
9sponsors
Outperforms 75% of sites

Therapeutic Area Benchmark — Croatia

Select a therapeutic area to compare against other sites in Croatia.

Competitor Comparison

Similar sites in the same country running a comparable number of trials (within ±30%), scored on how closely their trial portfolios match this one. Higher percentages mean a more similar profile.

Country: Croatia

Market Share

Country: Croatia

Therapeutic Area Market Share

Select a therapeutic area to view its disease coverage breakdown.

Heat Maps & Advanced Analytics

How often specific conditions appear in trials across this site and comparable sites from the same country. Each row is a site, each column a condition, and each cell the number of trials on it — darker means more activity.

Other Trials in Klinika za psihijatriju Vrapce

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Trial Sponsor Phase Status Start Date End Date
A Phase 3, Randomized, Double-Blind, Placebo-Controlled, Parallel-Group Study to Evaluate the Efficacy and Safety of KarXT + KarX-EC for the Treatment of Cognitive Impairment Associated with Mild to Moderate Alzheimer’s Disease (MINDSET 1)Bristol-Myers Squibb Services Unlimited CompanyPhase IIIRecruitingNov 2025

IMP list

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IMP Trials Status First start Last start
Trospium Chloride5Unknown2024-05-092025-11-18

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