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Kempenhaeghe

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Epilepsy Therapeutics Research

The Sleep Medicine Centre at Kempenhaeghe is advancing treatment options for epilepsy. Studies aim to lower seizure counts and evaluate long‑term safety of emerging medicines.

  • Refractory epilepsy
  • Primary generalized tonic‑clonic seizures
  • Focal onset seizures
  • Dravet syndrome and Lennox‑Gastaut syndrome
  • Idiopathic generalized epilepsy
  • Adjunctive cannabidiol therapy
  • Novel oral agents such as XEN1101 and BHV‑7000

A total of nine trials involving five investigators are currently recruiting or ongoing, offering patients access to cutting‑edge interventions while generating data that could reshape seizure management.

Sleep and Neurological Conditions

Research at the centre also addresses sleep disturbances that accompany neurological disease. The goal is to improve sleep quality and overall wellbeing through targeted therapies.

  • Insomnia management in adults
  • Sleep quality in multiple sclerosis
  • Impact of cannabidiol on sleep patterns
  • Non‑pharmacologic sleep interventions
  • Sleep monitoring in patients with epilepsy

By integrating sleep assessments into epilepsy trials, the site provides a holistic view of patient health, supporting better outcomes for both seizure control and restorative rest.

Site Overview

assignment
13
connected trials
corporate_fare
8
sponsors
science
8
IMPs

Activity Indicator

Last 6 months

2
Trials started
New activity detected vs previous period.
0
Trials started 6–12 months ago
13
Total trials linked
Highly Active
trending_upGrowing+100%
2
Mar
Apr
May
Jun
Jul
Aug

Trial Flow

How this site's trials are distributed across therapeutic areas and active substances (IMPs), and how they're positioned within their overall lifecycle status. Flow thickness represents the number of unique trials.

Therapeutic areaarrow_forwardIMParrow_forwardLifecycle status
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Compounds & Molecules Timeline

The time span of clinical-trial activity for the main active substances (IMPs) studied at this site over the last 8 years. Each bar runs from the earliest trial start to the most recent end; a substance with a trial still open has no recorded end and is shown as ongoing.

Trial span Ongoing Showing last 8 years
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Sponsor & Partnership

Top sponsors by active trials, and the ones that have come back for more than one study.

Active trials
8
Sponsors (total)
8
Active sponsors
4

Sponsor Network

Top 4 by active trials.

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Partnership History

Sponsors with repeated collaboration (≥ 2 trials).

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Sponsor Network Graph

How sponsors and therapeutic areas connect across this site's active trials: each link is at least one active trial shared between them, and bigger nodes mean more activity. Click a node to see its exact connections.

Country Benchmark

Compared to 271 other sites in The Netherlands

description
Trial volume
13
Outperforms 72% of sites
public
Therapeutic diversity
2areas
Outperforms 34% of sites
groups
Sponsor diversity
8sponsors
Outperforms 70% of sites

Therapeutic Area Benchmark — The Netherlands

Select a therapeutic area to compare against other sites in The Netherlands.

Competitor Comparison

Similar sites in the same country running a comparable number of trials (within ±30%), scored on how closely their trial portfolios match this one. Higher percentages mean a more similar profile.

Country: The Netherlands

Market Share

Country: The Netherlands

Therapeutic Area Market Share

Select a therapeutic area to view its disease coverage breakdown.

Heat Maps & Advanced Analytics

How often specific conditions appear in trials across this site and comparable sites from the same country. Each row is a site, each column a condition, and each cell the number of trials on it — darker means more activity.

Other Trials in Kempenhaeghe

lock Showing 1 of 13 trials — the rest is available on a paid plan.

Trial Sponsor Phase Status Start Date End Date
A Multicenter, Open-label, Long-term, Safety, Tolerability, and Efficacy Study of XEN1101 in Subjects Diagnosed With Epilepsy (X-TOLE4)Xenon Pharmaceuticals Inc.Phase IIIRecruitingFeb 2024

IMP list

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IMP Trials Status First start Last start
Azetukalner3Unknown2023-09-272024-02-14

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