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Karolinska Institutet

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Infectious Diseases and Neurological Infections

At Karolinska Institutet, research in bacterial infections and nervous system diseases includes studies on brain abscess, with a focus on finding effective treatment options that may support recovery while maintaining good clinical outcomes.

  • Comparing oral and intravenous antibiotic treatment for bacterial brain abscess
  • Evaluating whether a simpler treatment approach can be as effective as standard care

This work is aimed at improving treatment convenience and effectiveness for serious intracranial infection.

Autoimmune and Connective Tissue Disease Research

Clinical research in immune system diseases and skin and connective tissue diseases includes diffuse cutaneous systemic sclerosis, where investigators are studying strategies to improve survival and reduce the risk of major organ damage in early disease.

  • Testing stem cell transplantation as an early treatment option
  • Assessing how treatment strategies may help prevent organ failure

The goal is to identify a more effective approach for a severe autoimmune condition that can affect multiple organs.

Dermatology and Rare Genetic Skin Disorders

Work in skin and connective tissue diseases at this site also covers Netherton syndrome, a rare inherited disorder, with trials designed to assess whether a new topical therapy can safely control symptoms and improve patient well-being.

  • Studying a topical treatment for clinical safety and effectiveness
  • Exploring symptom control in a rare skin disease

This research supports the development of better options for people living with a difficult-to-manage dermatologic condition.

Hematology and Cancer Therapeutics

Clinical trials in hemic and lymphatic diseases focus on hematological malignancies, including leukemia and lymphoma, with research aimed at testing the safety and potential benefit of new cancer treatments for patients with advanced or relapsed disease.

  • Evaluating a new therapy for blood cancers such as AML, ALL, DLBCL, and multiple myeloma
  • Assessing treatment safety and tolerability in difficult-to-treat malignancies

These studies reflect an effort to expand options for patients with aggressive cancers who have limited standard treatments.

Site Overview

assignment
3
connected trials
corporate_fare
4
sponsors
science
13
IMPs

Activity Indicator

Last 6 months

0
Trials started
0
Trials started 6–12 months ago
3
Total trials linked
Moderately Active
trending_flatStable0%
Mar
Apr
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Trial Flow

How this site's trials are distributed across therapeutic areas and active substances (IMPs), and how they're positioned within their overall lifecycle status. Flow thickness represents the number of unique trials.

Therapeutic areaarrow_forwardIMParrow_forwardLifecycle status
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Compounds & Molecules Timeline

The time span of clinical-trial activity for the main active substances (IMPs) studied at this site over the last 8 years. Each bar runs from the earliest trial start to the most recent end; a substance with a trial still open has no recorded end and is shown as ongoing.

Trial span Ongoing Showing last 8 years
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Sponsor & Partnership

Top sponsors by active trials, and the ones that have come back for more than one study.

Active trials
3
Sponsors (total)
4
Active sponsors
4

Sponsor Network

Top 4 by active trials.

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Partnership History

Sponsors with repeated collaboration (≥ 2 trials).

No repeated partnerships found.

Sponsor Network Graph

How sponsors and therapeutic areas connect across this site's active trials: each link is at least one active trial shared between them, and bigger nodes mean more activity. Click a node to see its exact connections.

Country Benchmark

Compared to 188 other sites in Sweden

description
Trial volume
3
Outperforms 53% of sites
public
Therapeutic diversity
4areas
Outperforms 62% of sites
groups
Sponsor diversity
4sponsors
Outperforms 62% of sites

Therapeutic Area Benchmark — Sweden

Select a therapeutic area to compare against other sites in Sweden.

Competitor Comparison

Similar sites in the same country running a comparable number of trials (within ±30%), scored on how closely their trial portfolios match this one. Higher percentages mean a more similar profile.

Country: Sweden

Market Share

Country: Sweden

Therapeutic Area Market Share

Select a therapeutic area to view its disease coverage breakdown.

Heat Maps & Advanced Analytics

How often specific conditions appear in trials across this site and comparable sites from the same country. Each row is a site, each column a condition, and each cell the number of trials on it — darker means more activity.

Other Trials in Karolinska Institutet

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Trial Sponsor Phase Status Start Date End Date
Comparative Efficacy of Autologous Hematopoietic Stem Cell Transplantation Versus Immunosuppressive Therapy in Early Diffuse Cutaneous Systemic SclerosisUniversitair Medisch Centrum UtrechtPhase IIIRecruitingAug 2020

IMP list

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IMP Trials Status First start Last start
Amoxicillin1Unknown2021-05-022021-05-02

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