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Hospital Santa Maria Della Misericordia

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Oncology and Hematologic Malignancies

At Hospital Santa Maria Della Misericordia, a major share of research focuses on neoplasms and blood cancers, with studies in non-small cell lung cancer, melanoma, lymphoma, leukemia, multiple myeloma, and breast cancer. The trials are largely aimed at testing new cancer therapies, improving treatment combinations, and understanding how to better control disease recurrence and progression.

  • Research in advanced and resected lung cancer, including targeted and immunotherapy approaches
  • Studies in acute myeloid leukemia, acute lymphoblastic leukemia, and other leukemias with risk-adapted treatment strategies
  • Trials in lymphoma, multiple myeloma, and related hematologic cancers to improve response and durability of benefit
  • Investigations in melanoma and breast cancer focused on better disease control after standard treatment

Overall, the site supports a broad and active oncology program that combines precision medicine, immunotherapy, and new treatment options for both solid tumors and blood cancers.

Cardiovascular and Metabolic Research

The site also conducts important trials in cardiovascular diseases and nutritional and metabolic diseases, especially heart failure, atrial fibrillation, atherosclerotic cardiovascular disease, type 2 diabetes, obesity, and elevated lipoprotein(a). These studies aim to evaluate whether newer treatments can reduce complications, improve long-term outcomes, and lower the burden of chronic disease.

  • Trials in heart failure and related cardiovascular conditions to reduce events and improve clinical stability
  • Research on atrial fibrillation and coronary disease to refine prevention and treatment strategies
  • Studies in obesity, type 2 diabetes, and lipid disorders to address cardiometabolic risk
  • Work on lipoprotein(a) and atherosclerosis to better understand cardiovascular risk reduction

This therapeutic area reflects a strong interest in long-term disease prevention and in treatments that can support better heart and metabolic health.

Neurology, Eye Disease, and Immune-Mediated Conditions

Clinical research at the site spans nervous system diseases, eye diseases, and immune system diseases, including Alzheimer’s disease, migraine, multiple sclerosis, age-related macular degeneration, atopic dermatitis, prurigo nodularis, and rheumatoid arthritis. The purpose of these trials is often to improve symptom control, slow disease worsening, or test new options for chronic inflammatory and degenerative disorders.

  • Studies in Alzheimer’s disease and cognitive impairment focused on slowing decline and supporting brain health
  • Trials for migraine and headache disorders aimed at prevention and better symptom relief
  • Research in age-related macular degeneration and other eye conditions to preserve vision
  • Immune and inflammatory disease studies in atopic dermatitis, rheumatoid arthritis, and related skin and joint disorders

Within the Department of Medicine and Surgery, this work highlights a broad commitment to improving both quality of life and disease control in chronic conditions.

Respiratory, Skin, and Multisystem Disease Studies

The research portfolio at Hospital Santa Maria Della Misericordia also includes respiratory tract diseases, skin and connective tissue diseases, and other complex inflammatory conditions such as idiopathic pulmonary fibrosis, small-cell lung cancer, hidradenitis suppurativa, acne vulgaris, and systemic sclerosis. These trials are designed to evaluate new therapies, improve disease management, and address conditions with limited treatment options.

  • Research in idiopathic pulmonary fibrosis aimed at slowing lung function decline
  • Studies in small-cell lung cancer and other respiratory cancers to improve treatment effectiveness
  • Trials in hidradenitis suppurativa, acne vulgaris, and related skin disorders to reduce inflammation and symptoms
  • Investigations in systemic sclerosis and other multisystem immune conditions to better manage chronic disease burden

With many investigators contributing across these areas, the site supports a diverse portfolio that connects oncology, inflammation, and chronic organ disease research.

Site Overview

assignment
209
connected trials
corporate_fare
97
sponsors
science
337
IMPs

Activity Indicator

Last 6 months

7
Trials started
-50% vs previous period.
14
Trials started 6–12 months ago
209
Total trials linked
Highly Active
trending_downDeclining-50%
1
4
1
1
Mar
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Trial Flow

How this site's trials are distributed across therapeutic areas and active substances (IMPs), and how they're positioned within their overall lifecycle status. Flow thickness represents the number of unique trials.

Therapeutic areaarrow_forwardIMParrow_forwardLifecycle status

Top 3 of 12 therapeutic areas and 15 of 337 IMPs, ranked by number of trials.

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Compounds & Molecules Timeline

The time span of clinical-trial activity for the main active substances (IMPs) studied at this site over the last 8 years. Each bar runs from the earliest trial start to the most recent end; a substance with a trial still open has no recorded end and is shown as ongoing.

Trial span Ongoing Showing last 8 years

Top 40 of 328 compounds, ranked by number of trials.

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Sponsor & Partnership

Top sponsors by active trials, and the ones that have come back for more than one study.

Active trials
86
Sponsors (total)
97
Active sponsors
56

Sponsor Network

Top 56 by active trials.

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Partnership History

Sponsors with repeated collaboration (≥ 2 trials).

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Sponsor Network Graph

How sponsors and therapeutic areas connect across this site's active trials: each link is at least one active trial shared between them, and bigger nodes mean more activity. Click a node to see its exact connections.

Country Benchmark

Compared to 566 other sites in Italy

description
Trial volume
209
Outperforms 93% of sites
public
Therapeutic diversity
12areas
Outperforms 85% of sites
groups
Sponsor diversity
97sponsors
Outperforms 93% of sites

Therapeutic Area Benchmark — Italy

Select a therapeutic area to compare against other sites in Italy.

Competitor Comparison

Similar sites in the same country running a comparable number of trials (within ±30%), scored on how closely their trial portfolios match this one. Higher percentages mean a more similar profile.

Country: Italy

Market Share

Country: Italy

Therapeutic Area Market Share

Select a therapeutic area to view its disease coverage breakdown.

Heat Maps & Advanced Analytics

How often specific conditions appear in trials across this site and comparable sites from the same country. Each row is a site, each column a condition, and each cell the number of trials on it — darker means more activity.

Other Trials in Hospital Santa Maria Della Misericordia

lock Showing 1 of 209 trials — the rest is available on a paid plan.

Trial Sponsor Phase Status Start Date End Date
(21492 ARASTEP) A randomized, double-blind, placebo-controlled Phase 3 study of darolutamide plus androgen deprivation therapy (ADT) compared with placebo plus ADT in patients with high-risk biochemical recurrence (BCR) of prostate cancerBayer AG, Bayer Consumer Care AGPhase IIINot RecruitingOct 2023

IMP list

lock Showing 1 of 337 compounds — the rest is available on a paid plan.

IMP Trials Status First start Last start
Carboplatin21Unknown2018-08-092026-04-01

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