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Hospital Ruber Internacional

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Neurological Disorders – Epilepsy Research

Hospital Ruber Internacional’s neurology team is advancing the treatment of epilepsy and related encephalopathies through studies that assess safety and seizure‑reduction potential of emerging medicines.

  • Adult focal (partial onset) epilepsy
  • Refractory focal onset epilepsy
  • Dravet syndrome and Lennox‑Gastaut syndrome
  • Developmental and epileptic encephalopathies (DEE)
  • Epilepsy associated with tuberous sclerosis complex
  • KCNT1‑related developmental encephalopathy

The goal is to improve seizure control and quality of life for patients with rare and treatment‑resistant seizure disorders.

Oncology – Melanoma Immunotherapy

In the oncology unit, investigators are evaluating a biosimilar to Opdivo for patients with advanced melanoma, focusing on comparable efficacy and safety.

  • Previously untreated unresectable melanoma
  • Metastatic stage III/IV melanoma
  • First‑line immunotherapy with nivolumab biosimilar

These trials aim to broaden access to effective immunotherapy options while maintaining clinical outcomes.

Oncology – Prostate Cancer Hormone Therapy

The department conducts research on prostate cancer to determine the optimal duration of androgen deprivation therapy combined with salvage radiotherapy after surgical recurrence.

  • Recurrent prostate cancer post‑prostatectomy
  • Short‑term versus long‑term ADT
  • Salvage radiotherapy integration

Findings are expected to refine treatment protocols and improve long‑term disease‑free survival.

Neurodegenerative – Early Parkinson’s Disease

Studies at the site explore disease‑modifying strategies for Early Parkinson’s Disease, measuring impact on functional scores such as the MDS‑UPDRS.

  • Early-stage Parkinson’s patients
  • Movement Disorder Society Unified Parkinson’s Disease Rating Scale outcomes
  • Time to first worsening event

The research seeks to delay progression and maintain daily living abilities for individuals newly diagnosed with Parkinson’s.

Rare Genetic & Congenital Disorders

A dedicated program investigates therapies for congenital, hereditary and neonatal neurological conditions, targeting specific genetic mutations that drive severe seizure phenotypes.

  • KCNT1‑related developmental and epileptic encephalopathy
  • Other rare developmental encephalopathies
  • Genetically driven seizure disorders

By focusing on precision medicine, the trials aim to deliver targeted treatments that address the underlying genetic causes.

Site Overview

assignment
32
connected trials
corporate_fare
24
sponsors
science
28
IMPs

Activity Indicator

Last 6 months

1
Trials started
-50% vs previous period.
2
Trials started 6–12 months ago
32
Total trials linked
Highly Active
trending_downDeclining-50%
1
Mar
Apr
May
Jun
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Trial Flow

How this site's trials are distributed across therapeutic areas and active substances (IMPs), and how they're positioned within their overall lifecycle status. Flow thickness represents the number of unique trials.

Therapeutic areaarrow_forwardIMParrow_forwardLifecycle status

Top 5 of 6 therapeutic areas and 15 of 28 IMPs, ranked by number of trials.

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Compounds & Molecules Timeline

The time span of clinical-trial activity for the main active substances (IMPs) studied at this site over the last 8 years. Each bar runs from the earliest trial start to the most recent end; a substance with a trial still open has no recorded end and is shown as ongoing.

Trial span Ongoing Showing last 8 years
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Sponsor & Partnership

Top sponsors by active trials, and the ones that have come back for more than one study.

Active trials
13
Sponsors (total)
24
Active sponsors
10

Sponsor Network

Top 10 by active trials.

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Partnership History

Sponsors with repeated collaboration (≥ 2 trials).

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Sponsor Network Graph

How sponsors and therapeutic areas connect across this site's active trials: each link is at least one active trial shared between them, and bigger nodes mean more activity. Click a node to see its exact connections.

Country Benchmark

Compared to 567 other sites in Spain

description
Trial volume
32
Outperforms 84% of sites
public
Therapeutic diversity
6areas
Outperforms 80% of sites
groups
Sponsor diversity
24sponsors
Outperforms 85% of sites

Therapeutic Area Benchmark — Spain

Select a therapeutic area to compare against other sites in Spain.

Competitor Comparison

Similar sites in the same country running a comparable number of trials (within ±30%), scored on how closely their trial portfolios match this one. Higher percentages mean a more similar profile.

Country: Spain

Market Share

Country: Spain

Therapeutic Area Market Share

Select a therapeutic area to view its disease coverage breakdown.

Heat Maps & Advanced Analytics

How often specific conditions appear in trials across this site and comparable sites from the same country. Each row is a site, each column a condition, and each cell the number of trials on it — darker means more activity.

Other Trials in Hospital Ruber Internacional

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Trial Sponsor Phase Status Start Date End Date
A DOSE-BLINDED EXTENSION STUDY TO EVALUATE THE LONG-TERM EFFICACY, SAFETY, AND TOLERABILITY OF UCB0599 IN STUDY PARTICIPANTS WITH PARKINSON’S DISEASEUCB BiopharmaPhase IINot RecruitingDec 2022Mar 2025

IMP list

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IMP Trials Status First start Last start
Azetukalner3Unknown2019-05-282024-02-14

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