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Hospices Civils De Lyon

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Hemic and Lymphatic Diseases

The research program at Hospices Civils De Lyon concentrates on blood‑related and lymphatic disorders in children and young adults, testing innovative immunotherapies and targeted agents to enhance remission rates and long‑term survival.

  • Classical Hodgkin lymphoma in children and young adults
  • Relapsed/Refractory Aggressive Mature B-cell Neoplasms
  • Pediatric CD22-positive relapsed/refractory Acute Lymphoblastic Leukemia

Trials aim to evaluate safety, pharmacokinetics, and objective response, offering new therapeutic options for patients who have exhausted standard treatments.

Immune System Diseases

Focused investigations address immune‑mediated complications of transplantation, including the prevention and treatment of acute graft‑versus‑host disease through advanced antibody preparations and novel small molecules.

  • Steroid refractory Acute Graft versus host Disease
  • Pediatric and adult patients undergoing HSC allograft procedures with Thymoglobulin® packaging

The studies characterize the pharmacokinetic profile of Thymoglobulin® and compare the efficacy of investigational agents such as MC0518 against best available therapy, seeking safer graft outcomes.

Neoplasms

A broad oncology portfolio explores solid and hematologic cancers, integrating checkpoint inhibition and bispecific antibodies to improve response in hard‑to‑treat pediatric malignancies.

  • Classical Hodgkin lymphoma in children and young adults
  • Relapsed/Refractory Aggressive Mature B-cell Neoplasms
  • Pediatric CD22-positive relapsed/refractory Acute Lymphoblastic Leukemia

Research evaluates the safety and activity of agents like pembrolizumab and epcoritamab, aiming to establish new standards of care for patients with resistant disease.

Site Overview

assignment
5
connected trials
corporate_fare
5
sponsors
science
17
IMPs

Activity Indicator

Last 6 months

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Trials started
0
Trials started 6–12 months ago
5
Total trials linked
Active
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Trial Flow

How this site's trials are distributed across therapeutic areas and active substances (IMPs), and how they're positioned within their overall lifecycle status. Flow thickness represents the number of unique trials.

Therapeutic areaarrow_forwardIMParrow_forwardLifecycle status

Top 3 therapeutic areas and 15 of 17 IMPs, ranked by number of trials.

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Compounds & Molecules Timeline

The time span of clinical-trial activity for the main active substances (IMPs) studied at this site over the last 8 years. Each bar runs from the earliest trial start to the most recent end; a substance with a trial still open has no recorded end and is shown as ongoing.

Trial span Ongoing Showing last 8 years
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Sponsor & Partnership

Top sponsors by active trials, and the ones that have come back for more than one study.

Active trials
0
Sponsors (total)
5
Active sponsors
0

Sponsor Network

Top 10 by active trials.

No sponsors linked to active trials.

Partnership History

Sponsors with repeated collaboration (≥ 2 trials).

No repeated partnerships found.

Sponsor Network Graph

How sponsors and therapeutic areas connect across this site's active trials: each link is at least one active trial shared between them, and bigger nodes mean more activity. Click a node to see its exact connections.

Country Benchmark

Compared to 978 other sites in France

description
Trial volume
5
Outperforms 63% of sites
public
Therapeutic diversity
3areas
Outperforms 59% of sites
groups
Sponsor diversity
5sponsors
Outperforms 67% of sites

Therapeutic Area Benchmark — France

Select a therapeutic area to compare against other sites in France.

Competitor Comparison

Similar sites in the same country running a comparable number of trials (within ±30%), scored on how closely their trial portfolios match this one. Higher percentages mean a more similar profile.

Country: France

Market Share

Country: France

Therapeutic Area Market Share

Select a therapeutic area to view its disease coverage breakdown.

Heat Maps & Advanced Analytics

How often specific conditions appear in trials across this site and comparable sites from the same country. Each row is a site, each column a condition, and each cell the number of trials on it — darker means more activity.

Other Trials in Hospices Civils De Lyon

lock Showing 1 of 5 trials — the rest is available on a paid plan.

Trial Sponsor Phase Status Start Date End Date
Pharmacokinetics of anti-lymphocyte serum in the prevention of GvHD in children and adults receiving allogeneic hematopoietic stem cell transplantation - PHASAL-GA StudyHospices Civils De LyonPhase IIINot RecruitingJul 2023Nov 2025

IMP list

lock Showing 1 of 17 compounds — the rest is available on a paid plan.

IMP Trials Status First start Last start
Anti-T Lymphocyte Immunoglobulin For Human Use, Rabbit1Unknown2023-11-132023-11-13

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