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Hausarztzentrum Butendorf

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Cardiovascular Diseases

The research at Hausarztzentrum Butendorf targets atherosclerotic cardiovascular disease and related conditions, seeking to improve heart health by lowering LDL‑cholesterol, reducing cardiovascular risk, and managing heart failure.

  • Cardiovascular risk reduction in participants with elevated Lp(a)
  • Hypercholesterolemia management
  • Heart failure symptom improvement
  • Prevention of major adverse cardiovascular events
  • Evaluation of novel lipid‑lowering therapies

Through these studies, Hausarztzentrum Butendorf contributes to advancing preventive and therapeutic strategies for heart disease.

Digestive System Diseases

Investigations focus on functional gastrointestinal disorders, particularly irritable bowel syndrome, evaluating probiotic treatments to ease symptoms and improve quality of life.

  • Irritable bowel syndrome (diarrhoea‑predominant)
  • Gut microbiome modulation
  • Symptom frequency and severity reduction
  • Safety and tolerability of oral bacterial therapy
  • Patient‑reported outcome improvements

The centre’s work supports the development of non‑antibiotic options for digestive health.

Immune System Diseases

Studies explore immune‑related pathways and inflammatory processes, aiming to identify interventions that modulate the immune response and alleviate disease‑related symptoms.

  • Inflammatory response modulation
  • Evaluation of agents affecting immune signaling
  • Assessment of safety in immune‑targeted therapies
  • Biomarker analysis for immune activity
  • Potential applications across autoimmune conditions

By probing immune mechanisms, the site helps lay groundwork for future treatments.

Nutritional and Metabolic Diseases

Research addresses metabolic risk factors, especially elevated lipoprotein(a) and cholesterol, to develop strategies that lower cardiovascular burden through nutritional and pharmacologic means.

  • Elevated Lp(a) reduction studies
  • Metabolic risk profiling
  • Lipid metabolism intervention trials
  • Impact on cardiovascular outcomes
  • Safety evaluation of metabolic agents

These efforts aim to integrate metabolic health into broader cardiovascular prevention.

Otorhinolaryngologic Diseases

Clinical work includes evaluation of symptomatic treatments for acute pharyngitis, comparing new lozenge formulations with existing therapies to relieve throat discomfort.

  • Acute pharyngitis symptom relief
  • Efficacy of benzydamine hydrochloride lozenges
  • Comparison with active comparators
  • Patient comfort and recovery speed
  • Safety profile of topical agents

The site’s trials support evidence‑based options for common ENT infections.

Pathological Conditions, Signs and Symptoms

The centre investigates chronic pain syndromes, focusing on chronic back pain to assess novel analgesic compounds and improve functional outcomes.

  • Chronic back pain management
  • Evaluation of add‑on pain therapies
  • Impact on daily activity and quality of life
  • Safety and tolerability in long‑term use
  • Patient‑reported pain score improvements

These studies aim to expand therapeutic choices for individuals living with persistent pain.

Metabolism

Research delves into fundamental metabolic processes, particularly lipid and protein biomarkers, to understand how therapeutic interventions alter disease trajectories.

  • Biomarker changes in LDL‑cholesterol
  • Nt‑proBNP dynamics in heart failure
  • Lp(a) level modulation over time
  • Metabolic response to novel agents
  • Correlation of metabolic shifts with clinical outcomes

Insights from these studies may inform personalized metabolic management strategies.

Mental Disorders

Clinical trials focus on mild to moderate major depressive disorder, testing oral agents that aim to improve mood scores and achieve remission without relying on traditional antidepressants.

  • Major depressive disorder treatment efficacy
  • MADRS score improvement
  • Responder and remission rate analysis
  • Safety and tolerability of novel anxiolytic compounds
  • Impact on daily functioning and wellbeing

Hausarztzentrum Butendorf’s work contributes to expanding therapeutic options for mental health.

Site Overview

assignment
18
connected trials
corporate_fare
9
sponsors
science
62
IMPs

Activity Indicator

Last 6 months

4
Trials started
-20% vs previous period.
5
Trials started 6–12 months ago
18
Total trials linked
Highly Active
trending_downDeclining-20%
2
2
Mar
Apr
May
Jun
Jul
Aug

Trial Flow

How this site's trials are distributed across therapeutic areas and active substances (IMPs), and how they're positioned within their overall lifecycle status. Flow thickness represents the number of unique trials.

Therapeutic areaarrow_forwardIMParrow_forwardLifecycle status

Top 5 of 6 therapeutic areas and 15 of 62 IMPs, ranked by number of trials.

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Compounds & Molecules Timeline

The time span of clinical-trial activity for the main active substances (IMPs) studied at this site over the last 8 years. Each bar runs from the earliest trial start to the most recent end; a substance with a trial still open has no recorded end and is shown as ongoing.

Trial span Ongoing Showing last 8 years

Top 40 of 59 compounds, ranked by number of trials.

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Sponsor & Partnership

Top sponsors by active trials, and the ones that have come back for more than one study.

Active trials
10
Sponsors (total)
9
Active sponsors
7

Sponsor Network

Top 7 by active trials.

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Partnership History

Sponsors with repeated collaboration (≥ 2 trials).

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Sponsor Network Graph

How sponsors and therapeutic areas connect across this site's active trials: each link is at least one active trial shared between them, and bigger nodes mean more activity. Click a node to see its exact connections.

Country Benchmark

Compared to 2 161 other sites in Germany

description
Trial volume
18
Outperforms 89% of sites
public
Therapeutic diversity
8areas
Outperforms 94% of sites
groups
Sponsor diversity
9sponsors
Outperforms 85% of sites

Therapeutic Area Benchmark — Germany

Select a therapeutic area to compare against other sites in Germany.

Competitor Comparison

Similar sites in the same country running a comparable number of trials (within ±30%), scored on how closely their trial portfolios match this one. Higher percentages mean a more similar profile.

Country: Germany

Market Share

Country: Germany

Therapeutic Area Market Share

Select a therapeutic area to view its disease coverage breakdown.

Heat Maps & Advanced Analytics

How often specific conditions appear in trials across this site and comparable sites from the same country. Each row is a site, each column a condition, and each cell the number of trials on it — darker means more activity.

Other Trials in Hausarztzentrum Butendorf

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Trial Sponsor Phase Status Start Date End Date
A multi- center, randomized, double-blind, placebo-controlled parallel–group, dose-finding study to evaluate efficacy, safety, and tolerability of DII235 in adults with elevated Lipoprotein(a)Novartis Pharma AGPhase IINot RecruitingJan 2026

IMP list

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IMP Trials Status First start Last start
Adezunap4Unknown2023-11-022023-11-02

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