Groupement Hospitalier Eaubonne Montmorency Simone Veil

The Groupement Hospitalier Eaubonne Montmorency Simone Veil internal medicine team investigates severe infection‑related conditions, aiming to improve survival and reduce neurological complications in intensive care.

• Adult ICU patients with septic shock
• Early 7‑day use of levetiracetam to prevent delirium in sepsis
• Non‑inferiority of hydroxychloroquine combined with low‑dose corticosteroids for pulmonary involvement

Ongoing studies seek safer, more effective strategies for managing critical bacterial infections at the Eaubonne site.

Research in the cardiovascular field concentrates on preventing clot formation in patients at high risk of thrombosis following orthopaedic injury.

• Patients with lower limb trauma requiring immobilisation
• Comparison of Rivaroxaban versus low‑molecular weight heparin for primary VTE prophylaxis
• Use of the TRiP(cast) score to identify high‑risk individuals

The trials aim to establish safer anticoagulation protocols that reduce symptomatic thromboembolic events after casting.

The department’s ophthalmic research evaluates innovative drug‑delivery systems to preserve vision in chronic retinal conditions.

• Individuals with diabetic macular oedema
• Efficacy of a sustained‑release Ozurdex® intravitreal implant regimen
• Improvement in visual acuity over a 12‑month period

Findings are expected to guide treatment choices for patients facing progressive vision loss due to diabetes.

Studies focus on modulating immune‑mediated inflammation in organs such as the lungs and eyes, with the goal of reducing reliance on high‑dose steroids.

• Management of pulmonary sarcoidosis using low‑dose corticosteroids plus hydroxychloroquine
• Treatment of steroid‑dependent non‑infectious uveitis with adalimumab
• Comparison to standard therapy with mycophenolate mofetil

The objective is to demonstrate comparable effectiveness while minimizing side‑effects for patients with chronic immune disorders.

Research addresses the challenges of immobilisation after trauma, seeking to prevent secondary complications while supporting healing.

• Adults with lower limb trauma requiring brace or casting
• Evaluation of anticoagulation strategies to lower VTE risk
• Application of risk stratification tools such as the TRiP(cast) score

These investigations aim to refine post‑injury care pathways and reduce the incidence of preventable clotting events.

The respiratory research program explores interventions to improve lung function and reduce acute complications in critically ill patients.

• Patients experiencing respiratory distress in the ICU
• Assessment of hydroxychloroquine plus low‑dose steroids for long‑term pulmonary function
• Optimization of emergency tracheal intubation techniques to lower post‑intubation morbidity

Goals include enhancing oxygenation, decreasing delirium, and improving overall outcomes for those with severe respiratory illness.