local_hospital

Geniko Nosokomeio Nikaias Peiraia Ag. Panteleimon Geniko Nosokomeio Dytikis Attikis I

Address
Dimitrios Mantouvalos Str. 3, 184 54 Νikaia, Greece

Analytical, Diagnostic and Therapeutic Techniques and Equipment – Therapeutics

The gastroenterology unit is exploring innovative therapeutic devices and integrated diagnostic‑therapeutic solutions across several disease groups, including cardiovascular, digestive, hormonal and immune disorders. Trials aim to assess safety and effectiveness of new treatment modalities while improving patient monitoring.

  • Development of novel drug‑delivery platforms for inflammatory bowel disease
  • Evaluation of advanced imaging techniques for hypertension assessment
  • Assessment of therapeutic drug monitoring tools in immune‑mediated conditions

Geniko Nosokomeio Nikaias Peiraia hosts 18 active studies led by 10 investigators, fostering interdisciplinary collaboration.

Surgical Procedures – Operative

Research focuses on optimizing minimally invasive surgical approaches and peri‑procedural care for patients with gastrointestinal diseases. Studies evaluate bowel preparation regimens, endoscopic techniques, and operative management of disease complications.

  • Optimization of second‑line colonoscopy preparation protocols
  • Advancement of laparoscopic strategies for ulcerative colitis
  • Surgical outcomes in Crohn’s disease complications

The department leverages its endoscopic expertise to enhance operative safety and patient recovery.

Cardiovascular Diseases

A suite of trials targets major cardiovascular risk factors such as hypertension, atherosclerotic disease and heart failure. Objectives include testing combination antihypertensives, novel agents for lipoprotein(a) reduction, and therapies aimed at preventing heart‑failure events.

  • Fixed‑dose irbesartan/amlodipine for arterial hypertension
  • Baxdrostat plus dapagliflozin to lower heart‑failure risk
  • Zilebesiran impact on cardiovascular death and stroke
  • Muvalaplin evaluation for elevated Lp(a) cardiovascular events

Ongoing investigations seek to reduce morbidity in patients with high cardiovascular risk.

Digestive System Diseases

The centre conducts extensive research on inflammatory bowel disease, addressing both Crohn’s disease and ulcerative colitis. Trials assess biologic agents, novel small molecules, and supportive therapies to achieve clinical remission and mucosal healing.

  • Risankizumab maintenance therapy in ulcerative colitis
  • Tulisokibart efficacy in moderate to severe Crohn’s disease
  • Icotrokinra studies for ulcerative colitis remission
  • MK‑7240 investigation for Crohn’s disease
  • Evaluation of colonoscopy preparation effectiveness

With 18 active IBD studies, the department is a regional hub for advancing gastroenterology care.

Hormonal Diseases

Clinical investigations target endogenous Cushing’s syndrome and related metabolic disturbances. The focus is on therapies that mitigate hypercortisolemia‑induced hyperglycemia and improve endocrine control.

  • Fluasterone buccal tablet for hyperglycemia in Cushing’s syndrome
  • Assessment of metabolic outcomes after cortisol‑lowering interventions
  • Biomarker studies for endocrine disorder monitoring

These efforts aim to enhance quality of life for patients with hormonal imbalances.

Immune System Diseases

Trials examine novel immunomodulatory therapies for conditions such as IgA nephropathy and broader immune‑mediated disorders. Long‑term safety and efficacy are central objectives.

  • Long‑term safety evaluation of atacicept
  • Immune modulation strategies in IgA nephropathy
  • Investigations of immune response pathways in sepsis

The research program supports the development of targeted treatments for immune‑related diseases.

Pathological Conditions, Signs and Symptoms

Studies address acute conditions such as infection and sepsis, using early diagnostic markers to guide rapid therapeutic interventions. The goal is to improve survival through timely treatment decisions.

  • PROMISE trial evaluating early meropenem guided by PSP levels
  • Validation of qSOFA and NEWS2 scores for sepsis risk stratification
  • Assessment of symptom‑based endpoints in critical care trials

Emphasis is placed on translating rapid diagnostic insights into actionable clinical care.

Site Overview

assignment
15
connected trials
corporate_fare
11
sponsors
science
17
IMPs

Activity Indicator

Last 6 months

1
Trials started
-75% vs previous period.
4
Trials started 6–12 months ago
15
Total trials linked
Highly Active
trending_downDeclining-75%
1
Mar
Apr
May
Jun
Jul
Aug

Trial Flow

How this site's trials are distributed across therapeutic areas and active substances (IMPs), and how they're positioned within their overall lifecycle status. Flow thickness represents the number of unique trials.

Therapeutic areaarrow_forwardIMParrow_forwardLifecycle status

Top 5 of 7 therapeutic areas and 15 of 17 IMPs, ranked by number of trials.

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Compounds & Molecules Timeline

The time span of clinical-trial activity for the main active substances (IMPs) studied at this site over the last 8 years. Each bar runs from the earliest trial start to the most recent end; a substance with a trial still open has no recorded end and is shown as ongoing.

Trial span Ongoing Showing last 8 years
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Sponsor & Partnership

Top sponsors by active trials, and the ones that have come back for more than one study.

Active trials
8
Sponsors (total)
11
Active sponsors
8

Sponsor Network

Top 8 by active trials.

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Partnership History

Sponsors with repeated collaboration (≥ 2 trials).

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Sponsor Network Graph

How sponsors and therapeutic areas connect across this site's active trials: each link is at least one active trial shared between them, and bigger nodes mean more activity. Click a node to see its exact connections.

Country Benchmark

Compared to 173 other sites in Greece

description
Trial volume
15
Outperforms 73% of sites
public
Therapeutic diversity
7areas
Outperforms 80% of sites
groups
Sponsor diversity
11sponsors
Outperforms 72% of sites

Therapeutic Area Benchmark — Greece

Select a therapeutic area to compare against other sites in Greece.

Competitor Comparison

Similar sites in the same country running a comparable number of trials (within ±30%), scored on how closely their trial portfolios match this one. Higher percentages mean a more similar profile.

Country: Greece

Market Share

Country: Greece

Therapeutic Area Market Share

Select a therapeutic area to view its disease coverage breakdown.

Heat Maps & Advanced Analytics

How often specific conditions appear in trials across this site and comparable sites from the same country. Each row is a site, each column a condition, and each cell the number of trials on it — darker means more activity.

Other Trials in Geniko Nosokomeio Nikaias Peiraia Ag. Panteleimon Geniko Nosokomeio Dytikis Attikis I

lock Showing 1 of 15 trials — the rest is available on a paid plan.

Trial Sponsor Phase Status Start Date End Date
A Phase 3 Randomized, Double-Blind, Placebo-Controlled Study to Evaluate the Efficacy and Safety of Tulisokibart in Participants with Moderately to Severely Active Ulcerative ColitisMerck Sharp & Dohme LLCPhase IIINot RecruitingAug 2024

IMP list

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IMP Trials Status First start Last start
Tulisokibart3Unknown2024-08-202025-09-29

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