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Fondazione Luigi Maria Monti

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Skin and Connective Tissue Diseases

The Fondazione Luigi Maria Monti in Rome is running a broad portfolio in dermatology, with a strong focus on skin and connective tissue diseases such as bullous pemphigoid, epidermolysis bullosa, hidradenitis suppurativa, psoriasis, acne vulgaris, vitiligo, and diabetic foot ulcer. These studies mainly aim to improve symptom control, support wound healing, and assess the safety and effectiveness of new topical or systemic treatments.

  • Long-term safety and disease control in bullous pemphigoid and hidradenitis suppurativa
  • New treatment options for epidermolysis bullosa and related blistering disorders
  • Therapies for psoriasis, acne vulgaris, and vitiligo aimed at improving skin symptoms and quality of life
  • Wound-healing approaches for diabetic foot ulcer and other chronic skin conditions

Research at this site is centered on both long-term disease management and the evaluation of innovative skin-directed therapies for patients with chronic and often difficult-to-treat conditions.

Immune System Diseases

Clinical trials in immune system diseases at this site focus on conditions where the immune response plays a major role, including bullous pemphigoid, hidradenitis suppurativa, vitiligo, and psoriasis. The main purpose is to test whether new immune-targeted treatments can better control inflammation, reduce disease activity, and maintain results over time.

  • Immune-modulating treatments for bullous pemphigoid and hidradenitis suppurativa
  • Studies of vitiligo therapies designed to support repigmentation and disease stabilization
  • Evaluation of psoriasis treatments that target immune pathways involved in chronic skin inflammation
  • Research on the safety and durability of response for newer immunology-based therapies

These trials reflect a clear interest in refining immune-mediated disease care through treatments that may offer more sustained benefit and improved tolerability.

Neoplasms

The neoplasms portfolio at Fondazione Luigi Maria Monti includes studies in melanoma, Merkel cell carcinoma, cervical cancer, ovarian cancer, breast cancer, and other advanced solid tumors. These trials are designed to evaluate new cancer therapies, improve treatment effectiveness, and compare emerging combinations with current standards of care.

  • New melanoma treatments for advanced, metastatic, and mutation-specific disease
  • Immunotherapy studies in Merkel cell carcinoma and other difficult-to-treat cancers
  • Trials in ovarian cancer, cervical cancer, and breast cancer focused on treatment response and disease control
  • Research in broader solid tumors exploring whether novel immune-based approaches can improve outcomes

The cancer research program combines immunotherapy, targeted treatment strategies, and comparative effectiveness studies to address both common and rare advanced malignancies.

Site Overview

assignment
27
connected trials
corporate_fare
22
sponsors
science
31
IMPs

Activity Indicator

Last 6 months

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Trials started
-100% vs previous period.
3
Trials started 6–12 months ago
27
Total trials linked
Highly Active
trending_downDeclining-100%
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Trial Flow

How this site's trials are distributed across therapeutic areas and active substances (IMPs), and how they're positioned within their overall lifecycle status. Flow thickness represents the number of unique trials.

Therapeutic areaarrow_forwardIMParrow_forwardLifecycle status

Top 5 therapeutic areas and 15 of 31 IMPs, ranked by number of trials.

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Compounds & Molecules Timeline

The time span of clinical-trial activity for the main active substances (IMPs) studied at this site over the last 8 years. Each bar runs from the earliest trial start to the most recent end; a substance with a trial still open has no recorded end and is shown as ongoing.

Trial span Ongoing Showing last 8 years
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Sponsor & Partnership

Top sponsors by active trials, and the ones that have come back for more than one study.

Active trials
10
Sponsors (total)
22
Active sponsors
9

Sponsor Network

Top 9 by active trials.

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Partnership History

Sponsors with repeated collaboration (≥ 2 trials).

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Sponsor Network Graph

How sponsors and therapeutic areas connect across this site's active trials: each link is at least one active trial shared between them, and bigger nodes mean more activity. Click a node to see its exact connections.

Country Benchmark

Compared to 566 other sites in Italy

description
Trial volume
27
Outperforms 77% of sites
public
Therapeutic diversity
5areas
Outperforms 71% of sites
groups
Sponsor diversity
22sponsors
Outperforms 79% of sites

Therapeutic Area Benchmark — Italy

Select a therapeutic area to compare against other sites in Italy.

Competitor Comparison

Similar sites in the same country running a comparable number of trials (within ±30%), scored on how closely their trial portfolios match this one. Higher percentages mean a more similar profile.

Country: Italy

Market Share

Country: Italy

Therapeutic Area Market Share

Select a therapeutic area to view its disease coverage breakdown.

Heat Maps & Advanced Analytics

How often specific conditions appear in trials across this site and comparable sites from the same country. Each row is a site, each column a condition, and each cell the number of trials on it — darker means more activity.

Other Trials in Fondazione Luigi Maria Monti

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Trial Sponsor Phase Status Start Date End Date
A Phase 2, Multicenter, Randomized, Placebo-Controlled, Double-Blind, Dose-Ranging Trial to Evaluate the Efficacy and Safety of Zasocitinib in Participants with Nonsegmental Vitiligo.Takeda Development Center Americas Inc.Phase IIRecruitingFeb 2026

IMP list

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IMP Trials Status First start Last start
Pembrolizumab5Unknown2018-09-112023-11-27

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