Fakultna Nemocnica S Poliklinikou Nove Zamky

At Fakultna Nemocnica S Poliklinikou Nove Zamky, clinical research in digestive system diseases focuses on ulcerative colitis and Crohn’s disease. These studies are designed to assess new treatment options and better control inflammation, symptoms, and long-term disease activity.

• Moderately to severely active ulcerative colitis
• Moderately to severely active Crohn’s disease
• Testing therapies aimed at inducing and maintaining remission
• Evaluating safety, tolerability, and lasting treatment benefit

The site is contributing to research that may improve day-to-day disease management for people living with chronic bowel inflammation.

The Clinical Oncology department is actively involved in studies across neoplasms, with a strong focus on advanced cancers such as breast cancer, non-small cell lung cancer, and prostate cancer. The trials are mainly evaluating new therapies and treatment combinations to improve disease control and survival.

• Advanced or metastatic breast cancer
• Non-small cell lung cancer
• Metastatic castration-resistant prostate cancer
• Assessing effectiveness of novel anti-cancer treatments

Research at this hospital also includes broader solid tumor studies, reflecting a diverse oncology portfolio for patients with advanced disease.

Several trials at the site concentrate on hormone receptor-positive, HER2-negative breast cancer. These studies are exploring new ways to slow cancer progression and improve outcomes in patients whose disease has returned or spread.

• HR-positive, HER2-negative advanced or metastatic breast cancer
• Comparing new treatment strategies with current standard care
• Evaluating progression-free survival and treatment benefit
• Studying therapy combinations for resistant disease

This area highlights the site’s role in advancing more precise care for breast cancer patients with limited treatment options.

Research in skin and connective tissue diseases and immune system diseases includes studies in hidradenitis suppurativa and chronic spontaneous urticaria. The goal is to relieve troublesome symptoms, reduce flare-ups, and improve quality of life for people with chronic inflammatory skin disorders.

• Hidradenitis suppurativa
• Chronic spontaneous urticaria
• Testing therapies for symptom relief and disease control
• Assessing longer-term effectiveness and safety

These trials show the site’s interest in immune-driven conditions that can be difficult to manage with routine treatment alone.

The site is also taking part in research on immune system phenomena and related disorders such as fetal and neonatal alloimmune thrombocytopenia. This work aims to lower risk in pregnancy and improve protection for newborns affected by immune-related blood conditions.

• Fetal and neonatal alloimmune thrombocytopenia
• Evaluating prevention of severe complications in at-risk pregnancies
• Studying immune mechanisms that affect maternal and fetal health
• Improving safety outcomes for mothers and infants

Together with other immune-focused studies, this adds an important preventive medicine dimension to the research profile in Slovakia.

Another important area of research involves nutritional and metabolic diseases, especially cancer cachexia. These trials are looking at ways to address severe weight loss and weakness in people with advanced cancer, with the aim of improving body weight, appetite, and overall well-being.

• Cancer cachexia
• Supporting patients with advanced cancer and weight loss
• Evaluating treatment approaches that may improve nutrition and strength
• Measuring changes in appetite-related symptoms and body weight

This research complements the oncology program by focusing on a major complication that can affect treatment tolerance and daily functioning.