CRS Clinical Research Services Mannheim GmbH
- Address
- Grenadierstrasse 1, Neckarstadt, 68167 Mannheim, Germany
Cardiovascular Research
CRS Clinical Research Services Mannheim focuses on heart‑related conditions, exploring new treatments to lower blood pressure and improve vascular health.
- Arterial hypertension studies
- Combination therapy safety assessments
- Drug‑drug interaction evaluations
- Blood pressure response monitoring
The site’s investigators collaborate with industry partners to evaluate novel agents that may reduce cardiovascular risk.
Metabolic & Nutritional Studies
Research at the Mannheim clinic targets metabolic disorders such as Type 2 diabetes and obesity, aiming to improve glucose control and weight management.
- Glucose metabolism after mixed meal tolerance test
- Safety and tolerability of new antidiabetic agents
- Efficacy of combination treatments for overweight patients
- Impact of experimental drugs on insulin sensitivity
These trials assess how experimental drugs influence metabolic parameters in diverse patient groups.
Immunology & Viral Research
The center conducts studies on immune challenges, including HIV‑1 infection and vaccine responses to tuberculosis, to enhance protective immunity.
- RNA‑based vaccine safety in healthy volunteers
- Antibody BNT351 biological activity assessment
- Immune response monitoring after vaccination
- Safety profiling in participants with and without HIV
By enrolling both healthy volunteers and affected individuals, the site evaluates safety and immunogenicity of cutting‑edge biologics.
Bacterial & Mycotic Infection Trials
Investigations address bacterial conditions like bacterial vaginosis, testing antiseptic and antibiotic strategies to restore healthy microbiota.
- Chlorhexidine vaginal antisepsis evaluation
- Oral metronidazole pre‑treatment study
- FB301 impact on vaginal microbiome composition
- Combined therapy effectiveness on symptom reduction
These projects seek to reduce recurrence rates and improve quality of life for women experiencing recurrent infections.
Hepatic & Renal Studies
Trials examine chronic organ diseases, focusing on chronic liver disease and chronic kidney disease, to assess safety of herbal extracts and metabolic modulators.
- Silymarin‑standardized milk thistle extract safety
- MASLD (metabolic dysfunction‑associated steatotic liver disease) tolerability
- Renal function monitoring during novel therapy
- Biomarker analysis for disease progression
The research aims to identify therapies that can slow disease progression and support organ health.
Broad Clinical Research
Beyond defined therapeutic areas, CRS Clinical Research Services Mannheim conducts exploratory studies in healthy volunteers to understand drug absorption and interaction.
- Pharmacokinetic profiling of new compounds
- Food effect on drug bioavailability
- Combination formulation uptake assessment
- Safety monitoring in phase‑I healthy subject trials
These foundational investigations inform later disease‑specific trials and contribute to overall drug development knowledge.
Site Overview
Activity Indicator
Last 6 months
Trial Flow
How this site's trials are distributed across therapeutic areas and active substances (IMPs), and how they're positioned within their overall lifecycle status. Flow thickness represents the number of unique trials.
Top 5 of 6 therapeutic areas and 13 of 14 IMPs, ranked by number of trials.
Compounds & Molecules Timeline
The time span of clinical-trial activity for the main active substances (IMPs) studied at this site over the last 8 years. Each bar runs from the earliest trial start to the most recent end; a substance with a trial still open has no recorded end and is shown as ongoing.
Sponsor & Partnership
Top sponsors by active trials, and the ones that have come back for more than one study.
Sponsor Network
Top 8 by active trials.
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Partnership History
Sponsors with repeated collaboration (≥ 2 trials).
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Sponsor Network Graph
How sponsors and therapeutic areas connect across this site's active trials: each link is at least one active trial shared between them, and bigger nodes mean more activity. Click a node to see its exact connections.
Country Benchmark
Compared to 2 161 other sites in Germany
Therapeutic Area Benchmark — Germany
Select a therapeutic area to compare against other sites in Germany.
Competitor Comparison
Similar sites in the same country running a comparable number of trials (within ±30%), scored on how closely their trial portfolios match this one. Higher percentages mean a more similar profile.
Country: Germany
Market Share
Country: Germany
Therapeutic Area Market Share
Select a therapeutic area to view its disease coverage breakdown.
Heat Maps & Advanced Analytics
How often specific conditions appear in trials across this site and comparable sites from the same country. Each row is a site, each column a condition, and each cell the number of trials on it — darker means more activity.
Other Trials in CRS Clinical Research Services Mannheim GmbH
lock Showing 1 of 28 trials — the rest is available on a paid plan.
| Trial | Sponsor | Phase | Status | Start Date | End Date |
|---|---|---|---|---|---|
| A Bioequivalence Study of Netupitant/Palonosetron Oral Suspension versus Hard Capsules in Healthy Volunteers | Helsinn Birex Pharmaceuticals Limited, Helsinn Healthcare S.A. | Phase I | Not Yet Recruiting | — | — |
IMP list
lock Showing 1 of 14 compounds — the rest is available on a paid plan.
| IMP | Trials | Status | First start | Last start |
|---|---|---|---|---|
| Azd5004 | 3 | Unknown | 2024-12-11 | 2025-02-24 |
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