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Clinique Tivoli Ducos

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Digestive System Diseases

Clinique Tivoli Ducos is advancing treatment for colorectal cancer and related gastrointestinal malignancies, aiming to improve survival through innovative chemotherapy and immunotherapy combinations while also exploring strategies for esophageal adenocarcinoma and gastric adenocarcinoma.

  • Adjuvant chemotherapy optimization for stage II colon cancer
  • Immunotherapy plus chemotherapy for microsatellite stable metastatic colorectal cancer
  • Neoadjuvant approaches in locally advanced rectal cancer
  • Targeted therapy for KRAS G12C‑mutated colorectal tumors
  • Evaluation of intra‑operative fluorescence imaging to reduce anastomotic leaks

The research focuses on testing new therapeutic regimens, reducing treatment‑related complications, and personalizing care based on molecular markers, with the goal of extending disease‑free intervals for patients.

Female Urogenital Diseases and Pregnancy Complications

The department conducts trials on ER+/HER2‑negative metastatic breast cancer, endometrial cancer, and ovarian cancer, seeking to refine hormone‑driven therapies, evaluate de‑escalation of HER2‑targeted agents, and integrate novel targeted drugs to enhance outcomes for women.

  • De‑escalation of HER2‑targeted therapy in metastatic breast cancer with ctDNA monitoring
  • Adjuvant CDK4/6 inhibitor strategies for hormone‑positive early breast cancer
  • Novel hormonal and immunotherapy combinations for high‑risk endometrial cancer
  • PARP‑inhibitor based regimens for platinum‑resistant ovarian cancer
  • Personalized adjuvant treatment decisions guided by gene‑expression profiling

These studies aim to improve disease‑free survival, reduce overtreatment, and tailor therapies to the molecular profile of each tumor, offering women more precise and effective options.

Neoplasms

Across a broad oncology portfolio, Clinique Tivoli Ducos investigates muscle‑invasive bladder cancer, triple‑negative breast cancer, and high‑risk HER2‑positive breast cancer, focusing on antibody‑drug conjugates, immune checkpoint blockade, and combination regimens to boost response rates and quality of life.

  • Antibody‑drug conjugate trials in HER2‑positive breast disease
  • Immunotherapy combined with chemotherapy for triple‑negative breast cancer
  • Neoadjuvant checkpoint inhibition before radical cystectomy in bladder cancer
  • Combination targeted agents for advanced gastric and gastro‑oesophageal junction adenocarcinoma
  • Evaluation of patient‑reported outcomes and digital health tools during treatment

The overarching purpose is to assess the effectiveness of new therapeutic combinations, improve survival metrics, and enhance patient‑centred care across diverse cancer types.

Site Overview

assignment
28
connected trials
corporate_fare
14
sponsors
science
60
IMPs

Activity Indicator

Last 6 months

4
Trials started
-33% vs previous period.
6
Trials started 6–12 months ago
28
Total trials linked
Highly Active
trending_downDeclining-33%
1
2
1
Mar
Apr
May
Jun
Jul
Aug

Trial Flow

How this site's trials are distributed across therapeutic areas and active substances (IMPs), and how they're positioned within their overall lifecycle status. Flow thickness represents the number of unique trials.

Therapeutic areaarrow_forwardIMParrow_forwardLifecycle status

Top 3 therapeutic areas and 15 of 60 IMPs, ranked by number of trials.

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Compounds & Molecules Timeline

The time span of clinical-trial activity for the main active substances (IMPs) studied at this site over the last 8 years. Each bar runs from the earliest trial start to the most recent end; a substance with a trial still open has no recorded end and is shown as ongoing.

Trial span Ongoing Showing last 8 years

Top 40 of 57 compounds, ranked by number of trials.

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Sponsor & Partnership

Top sponsors by active trials, and the ones that have come back for more than one study.

Active trials
17
Sponsors (total)
14
Active sponsors
9

Sponsor Network

Top 9 by active trials.

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Partnership History

Sponsors with repeated collaboration (≥ 2 trials).

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Sponsor Network Graph

How sponsors and therapeutic areas connect across this site's active trials: each link is at least one active trial shared between them, and bigger nodes mean more activity. Click a node to see its exact connections.

Country Benchmark

Compared to 978 other sites in France

description
Trial volume
28
Outperforms 84% of sites
public
Therapeutic diversity
3areas
Outperforms 59% of sites
groups
Sponsor diversity
14sponsors
Outperforms 81% of sites

Therapeutic Area Benchmark — France

Select a therapeutic area to compare against other sites in France.

Competitor Comparison

Similar sites in the same country running a comparable number of trials (within ±30%), scored on how closely their trial portfolios match this one. Higher percentages mean a more similar profile.

Country: France

Market Share

Country: France

Therapeutic Area Market Share

Select a therapeutic area to view its disease coverage breakdown.

Heat Maps & Advanced Analytics

How often specific conditions appear in trials across this site and comparable sites from the same country. Each row is a site, each column a condition, and each cell the number of trials on it — darker means more activity.

Other Trials in Clinique Tivoli Ducos

lock Showing 1 of 28 trials — the rest is available on a paid plan.

Trial Sponsor Phase Status Start Date End Date
De-escalation of endocrine therapy in postmenopausal women with low-risk HR+ HER2- low Luminal A early breast cancer: a single-arm study of omission versus combination therapyUnicancerPhase IINot Yet Recruiting

IMP list

lock Showing 1 of 60 compounds — the rest is available on a paid plan.

IMP Trials Status First start Last start
Fluorouracil9Unknown2017-03-272026-05-07

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