Clinique Mathilde
- Address
- 7 Boulevard De L Europe, 76100 Rouen, France
Clinique Mathilde - Oncology and Ophthalmology Research Center
Clinique Mathilde is a distinguished clinical research center with extensive expertise in oncology and ophthalmology trials. The facility demonstrates particular strength in conducting complex phase III studies across multiple cancer types and retinal diseases, contributing to advancement in both surgical and medical therapeutic approaches.
- Gastrointestinal and gynecological oncology including anal squamous cell carcinoma, esophagogastric adenocarcinoma, ovarian cancer, and advanced treatment protocols with HIPEC
- Breast and prostate cancer management with focus on hormone receptor-positive tumors and adjuvant therapies in special populations
- Retinal diseases and age-related macular degeneration, including geographic atrophy, macular telangiectasia, and diabetic macular edema
- Novel drug delivery systems and combination therapies for neovascular AMD and complement-mediated retinal conditions
The center's oncology portfolio spans diverse treatment modalities including induction chemotherapy, chemoradiotherapy, and hyperthermic intraperitoneal chemotherapy (HIPEC), with particular emphasis on locally advanced and metastatic disease management. In ophthalmology, the facility investigates cutting-edge approaches including intravitreal implants, complement inhibition, and sustained-release drug delivery systems such as the Port Delivery System with ranibizumab, demonstrating commitment to improving long-term outcomes and quality of life for patients with vision-threatening conditions.
Site Overview
Activity Indicator
Last 6 months
Trial Flow
How this site's trials are distributed across therapeutic areas and active substances (IMPs), and how they're positioned within their overall lifecycle status. Flow thickness represents the number of unique trials.
Top 4 therapeutic areas and 15 of 20 IMPs, ranked by number of trials.
Compounds & Molecules Timeline
The time span of clinical-trial activity for the main active substances (IMPs) studied at this site over the last 8 years. Each bar runs from the earliest trial start to the most recent end; a substance with a trial still open has no recorded end and is shown as ongoing.
Sponsor & Partnership
Top sponsors by active trials, and the ones that have come back for more than one study.
Sponsor Network
Top 4 by active trials.
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Partnership History
Sponsors with repeated collaboration (≥ 2 trials).
Sponsor Network Graph
How sponsors and therapeutic areas connect across this site's active trials: each link is at least one active trial shared between them, and bigger nodes mean more activity. Click a node to see its exact connections.
Country Benchmark
Compared to 978 other sites in France
Therapeutic Area Benchmark — France
Select a therapeutic area to compare against other sites in France.
Competitor Comparison
Similar sites in the same country running a comparable number of trials (within ±30%), scored on how closely their trial portfolios match this one. Higher percentages mean a more similar profile.
Country: France
Market Share
Country: France
Therapeutic Area Market Share
Select a therapeutic area to view its disease coverage breakdown.
Heat Maps & Advanced Analytics
How often specific conditions appear in trials across this site and comparable sites from the same country. Each row is a site, each column a condition, and each cell the number of trials on it — darker means more activity.
Other Trials in Clinique Mathilde
lock Showing 1 of 9 trials — the rest is available on a paid plan.
| Trial | Sponsor | Phase | Status | Start Date | End Date |
|---|---|---|---|---|---|
| Efficacy of Dimethyl Fumarate in Reducing Geographic Atrophy Progression in Patients with Dry Age-Related Macular Degeneration: A 12-Month Comparative Study | Assistance Publique Hopitaux De Paris | Phase II | Recruiting | Jun 2024 | — |
IMP list
lock Showing 1 of 20 compounds — the rest is available on a paid plan.
| IMP | Trials | Status | First start | Last start |
|---|---|---|---|---|
| Cisplatin | 2 | Unknown | 2019-05-02 | 2024-02-26 |
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