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Children's Hospital Zagreb

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Therapeutics and Medical Devices

The department is advancing pediatric therapeutics by testing innovative medicines and diagnostic tools across several disease groups, aiming to improve safety and effectiveness for young patients.

  • Evaluation of novel drug candidates for pediatric use
  • Integration of advanced diagnostic equipment in clinical practice
  • Development of personalized treatment algorithms
  • Monitoring of long‑term safety in children
  • Collaboration with research laboratories for biomarker discovery

Children’s Hospital Zagreb supports these efforts with a dedicated pediatric research team and state‑of‑the‑art facilities.

Digestive System Diseases

Studies focus on ulcerative colitis in children and adolescents, seeking therapies that induce remission and sustain disease control while minimizing side effects.

  • Induction strategies for pediatric inflammatory bowel disease
  • Maintenance regimens to prevent relapse
  • Impact of treatment on growth and nutrition
  • Quality‑of‑life assessments for young patients
  • Long‑term outcome monitoring

The hospital’s gastroenterology unit collaborates closely with families to tailor care plans.

Hemic and Lymphatic Diseases

Research targets anemia associated with chronic kidney disease and childhood acute lymphoblastic leukemia, aiming to enhance treatment response and reduce treatment‑related complications.

  • Therapeutic approaches to correct anemia in pediatric CKD
  • Risk‑adapted chemotherapy protocols for ALL
  • Integration of immunotherapy for B‑cell precursor leukemia
  • Genetic and minimal residual disease profiling at diagnosis
  • Strategies to lower induction‑phase mortality

By refining risk classification, the site strives to boost survival rates for young patients with blood‑related disorders.

Nervous System Diseases

The unit investigates pediatric multiple sclerosis and neurogenic detrusor overactivity, evaluating therapies that limit relapses and improve bladder function, respectively.

  • Comparison of disease‑modifying agents for pediatric MS
  • Assessment of relapse frequency and disability progression
  • Non‑invasive management of bladder overactivity
  • Safety monitoring of long‑term neurological treatments
  • Functional outcome measures for children

Multidisciplinary teams combine neurology and urology expertise to deliver comprehensive care.

Pathological Conditions, Signs and Symptoms

A broader initiative addresses the identification and management of clinical signs across pediatric conditions, aiming to sharpen diagnostic accuracy and symptom relief.

  • Standardized symptom assessment tools for children
  • Early detection markers for emerging diseases
  • Integration of patient‑reported outcomes into care pathways
  • Holistic strategies to manage pain and fatigue
  • Evaluation of health‑related quality of life metrics

The hospital emphasizes a child‑centered approach that balances medical intervention with overall wellbeing.

Site Overview

assignment
10
connected trials
corporate_fare
8
sponsors
science
14
IMPs

Activity Indicator

Last 6 months

0
Trials started
0
Trials started 6–12 months ago
10
Total trials linked
Highly Active
trending_flatStable0%
Mar
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May
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Trial Flow

How this site's trials are distributed across therapeutic areas and active substances (IMPs), and how they're positioned within their overall lifecycle status. Flow thickness represents the number of unique trials.

Therapeutic areaarrow_forwardIMParrow_forwardLifecycle status

Top 5 of 9 therapeutic areas and 11 of 14 IMPs, ranked by number of trials.

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Compounds & Molecules Timeline

The time span of clinical-trial activity for the main active substances (IMPs) studied at this site over the last 8 years. Each bar runs from the earliest trial start to the most recent end; a substance with a trial still open has no recorded end and is shown as ongoing.

Trial span Ongoing Showing last 8 years
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Sponsor & Partnership

Top sponsors by active trials, and the ones that have come back for more than one study.

Active trials
5
Sponsors (total)
8
Active sponsors
5

Sponsor Network

Top 5 by active trials.

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Partnership History

Sponsors with repeated collaboration (≥ 2 trials).

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Sponsor Network Graph

How sponsors and therapeutic areas connect across this site's active trials: each link is at least one active trial shared between them, and bigger nodes mean more activity. Click a node to see its exact connections.

Country Benchmark

Compared to 60 other sites in Croatia

description
Trial volume
10
Outperforms 68% of sites
public
Therapeutic diversity
9areas
Outperforms 83% of sites
groups
Sponsor diversity
8sponsors
Outperforms 70% of sites

Therapeutic Area Benchmark — Croatia

Select a therapeutic area to compare against other sites in Croatia.

Competitor Comparison

Similar sites in the same country running a comparable number of trials (within ±30%), scored on how closely their trial portfolios match this one. Higher percentages mean a more similar profile.

Country: Croatia

Market Share

Country: Croatia

Therapeutic Area Market Share

Select a therapeutic area to view its disease coverage breakdown.

Heat Maps & Advanced Analytics

How often specific conditions appear in trials across this site and comparable sites from the same country. Each row is a site, each column a condition, and each cell the number of trials on it — darker means more activity.

Other Trials in Children's Hospital Zagreb

lock Showing 1 of 10 trials — the rest is available on a paid plan.

Trial Sponsor Phase Status Start Date End Date
A Phase 2 Dose Finding Study Evaluating the Safety and Efficacy of Linaclotide in Pediatric Subjects 6 Months to Less Than 2 Years of Age with Functional Constipation (FC).AbbVie Deutschland GmbH & Co. KGPhase IINot RecruitingDec 2023May 2025

IMP list

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IMP Trials Status First start Last start
Epoetin Alfa1Unknown2023-12-212023-12-21

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