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Charite Research Organisation GmbH

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Oncology

Charité Research Organisation advances cancer care by testing innovative therapies for a wide range of solid tumors and hematologic malignancies.

  • Advanced melanoma
  • Non‑small cell lung cancer
  • Colorectal cancer
  • Breast cancer (HER2‑positive and HER2‑low)
  • High‑grade serous ovarian cancer
  • Renal cell carcinoma
  • Lymphoma (diffuse large B‑cell, Hodgkin’s, peripheral T‑cell)

The trials aim to evaluate efficacy and safety of targeted agents and immunotherapies, helping to improve treatment outcomes for patients across Berlin and beyond.

Immunology & Autoimmune Disorders

Research at Charité focuses on immune‑mediated diseases, exploring new biologics that modulate the immune response.

  • Atopic dermatitis
  • Plaque psoriasis
  • Ulcerative colitis
  • Crohn’s disease
  • Systemic lupus erythematosus
  • Chronic inflammatory demyelinating polyneuropathy

These studies assess whether novel agents can reduce disease activity and improve quality of life for individuals living with chronic inflammation.

Metabolic & Endocrine Disorders

The site conducts trials targeting metabolic health, including obesity and diabetes management.

  • Type 2 Diabetes Mellitus
  • Obesity
  • Metabolic syndrome
  • Nutritional deficiencies

Objectives include testing agents that promote weight loss, improve glycemic control, and address associated cardiovascular risk factors.

Cardiovascular and Respiratory Diseases

Charité’s program evaluates therapies for cardiopulmonary conditions, aiming to alleviate symptoms and slow disease progression.

  • Chronic obstructive pulmonary disease (COPD)
  • Mild to moderate asthma
  • Hypertension
  • Heart failure

The research measures functional improvement, reduction in exacerbations, and overall patient well‑being.

Infectious Diseases

Studies at Charité address serious bacterial infections and sepsis, testing new antimicrobial strategies.

  • Clostridioides difficile infection
  • Sepsis
  • Septic shock

Trials focus on safety and efficacy of novel antibiotics or adjunctive therapies to improve survival and recovery rates.

Site Overview

assignment
134
connected trials
corporate_fare
80
sponsors
science
162
IMPs

Activity Indicator

Last 6 months

7
Trials started
+133% vs previous period.
3
Trials started 6–12 months ago
134
Total trials linked
Highly Active
trending_upGrowing+133%
1
1
1
2
1
1
Mar
Apr
May
Jun
Jul
Aug

Trial Flow

How this site's trials are distributed across therapeutic areas and active substances (IMPs), and how they're positioned within their overall lifecycle status. Flow thickness represents the number of unique trials.

Therapeutic areaarrow_forwardIMParrow_forwardLifecycle status

Top 5 of 25 therapeutic areas and 15 of 162 IMPs, ranked by number of trials.

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Compounds & Molecules Timeline

The time span of clinical-trial activity for the main active substances (IMPs) studied at this site over the last 8 years. Each bar runs from the earliest trial start to the most recent end; a substance with a trial still open has no recorded end and is shown as ongoing.

Trial span Ongoing Showing last 8 years

Top 40 of 161 compounds, ranked by number of trials.

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Sponsor & Partnership

Top sponsors by active trials, and the ones that have come back for more than one study.

Active trials
47
Sponsors (total)
80
Active sponsors
36

Sponsor Network

Top 36 by active trials.

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Partnership History

Sponsors with repeated collaboration (≥ 2 trials).

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Sponsor Network Graph

How sponsors and therapeutic areas connect across this site's active trials: each link is at least one active trial shared between them, and bigger nodes mean more activity. Click a node to see its exact connections.

Country Benchmark

Compared to 2 161 other sites in Germany

description
Trial volume
134
Outperforms 98% of sites
public
Therapeutic diversity
28areas
Outperforms 99% of sites
groups
Sponsor diversity
80sponsors
Outperforms 99% of sites

Therapeutic Area Benchmark — Germany

Select a therapeutic area to compare against other sites in Germany.

Competitor Comparison

Similar sites in the same country running a comparable number of trials (within ±30%), scored on how closely their trial portfolios match this one. Higher percentages mean a more similar profile.

Country: Germany

Market Share

Country: Germany

Therapeutic Area Market Share

Select a therapeutic area to view its disease coverage breakdown.

Heat Maps & Advanced Analytics

How often specific conditions appear in trials across this site and comparable sites from the same country. Each row is a site, each column a condition, and each cell the number of trials on it — darker means more activity.

Other Trials in Charite Research Organisation GmbH

lock Showing 1 of 134 trials — the rest is available on a paid plan.

Trial Sponsor Phase Status Start Date End Date
A 24-Month, Multi-Centre, Open Label Phase IV Post Authorisation Efficacy Study to Evaluate the Efficacy, Safety and Immunogenicity of Daily Subcutaneous Metreleptin Treatment in Patients with Partial LipodystrophyChiesi Farmaceutici S.p.A.Phase IIIRecruitingDec 2023

IMP list

lock Showing 1 of 162 compounds — the rest is available on a paid plan.

IMP Trials Status First start Last start
Pembrolizumab13Unknown2017-06-082025-11-07

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