Centrul De Excelenta In Rinologie S.R.L.
- Address
- Strada Toporasi Nr 51 Parter, Block C2, 200222 Craiova, Romania
Centrul De Excelenta In Rinologie S.R.L. - Center of Excellence in Rhinology
The Center of Excellence in Rhinology is a specialized medical research facility dedicated to advancing the understanding and treatment of chronic rhinosinusitis and related sinonasal disorders. The center focuses on evaluating novel biologic therapies and innovative treatment approaches for patients with inadequately controlled rhinosinusitis conditions.
- Chronic Rhinosinusitis With Nasal Polyps (CRSwNP) - investigating targeted biologic therapies including lebrikizumab and itepekimab
- Chronic Rhinosinusitis Without Nasal Polyps - proof of concept studies for anti-IL-33 monoclonal antibody treatments
- Advanced rhinologic interventions combining intranasal corticosteroids with novel immunomodulatory agents
The research center participates in multiple Phase 3 clinical trials evaluating cutting-edge monoclonal antibody therapies targeting specific inflammatory pathways, including IL-33 inhibition. Their clinical studies focus on objective outcomes such as endoscopic nasal polyp scores, sinus opacification measurements, and patient-reported symptom severity, particularly nasal congestion. This comprehensive approach positions the center at the forefront of developing more effective therapeutic options for patients with difficult-to-treat respiratory tract diseases affecting the sinonasal cavity.
Site Overview
Activity Indicator
Last 6 months
Trial Flow
How this site's trials are distributed across therapeutic areas and active substances (IMPs), and how they're positioned within their overall lifecycle status. Flow thickness represents the number of unique trials.
Compounds & Molecules Timeline
The time span of clinical-trial activity for the main active substances (IMPs) studied at this site over the last 8 years. Each bar runs from the earliest trial start to the most recent end; a substance with a trial still open has no recorded end and is shown as ongoing.
Sponsor & Partnership
Top sponsors by active trials, and the ones that have come back for more than one study.
Sponsor Network
Top 2 by active trials.
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Partnership History
Sponsors with repeated collaboration (≥ 2 trials).
Sponsor Network Graph
How sponsors and therapeutic areas connect across this site's active trials: each link is at least one active trial shared between them, and bigger nodes mean more activity. Click a node to see its exact connections.
Country Benchmark
Compared to 442 other sites in Romania
Therapeutic Area Benchmark — Romania
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Competitor Comparison
Similar sites in the same country running a comparable number of trials (within ±30%), scored on how closely their trial portfolios match this one. Higher percentages mean a more similar profile.
Country: Romania
Market Share
Country: Romania
Therapeutic Area Market Share
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Heat Maps & Advanced Analytics
How often specific conditions appear in trials across this site and comparable sites from the same country. Each row is a site, each column a condition, and each cell the number of trials on it — darker means more activity.
Other Trials in Centrul De Excelenta In Rinologie S.R.L.
lock Showing 1 of 4 trials — the rest is available on a paid plan.
| Trial | Sponsor | Phase | Status | Start Date | End Date |
|---|---|---|---|---|---|
| Efficacy and Safety Evaluation of Lebrikizumab in Chronic Rhinosinusitis with Nasal Polyps on Intranasal Corticosteroids: A Phase 3 Randomized Controlled Trial | Eli Lilly & Co. | Phase III | Recruiting | Oct 2024 | — |
IMP list
lock Showing 1 of 3 compounds — the rest is available on a paid plan.
| IMP | Trials | Status | First start | Last start |
|---|---|---|---|---|
| Itepekimab | 3 | Unknown | 2025-03-20 | 2026-06-23 |
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